scholarly journals Extramammary Paget’s Disease and Melanoma: 2 Cases of Double Cancers

2020 ◽  
Vol 12 (2) ◽  
pp. 107-113
Author(s):  
Erika Lydrup ◽  
Jais Oliver Berg ◽  
Sofie Vetli Hjorth ◽  
Lisbet Rosenkrantz Hølmich ◽  
Jørgen Lock-Andersen ◽  
...  

Extramammary Paget’s disease (EMPD) is a rare intraepidermal neoplastic disease. There is a well-known relationship between EMPD and underlying malignancy. However, only a few cases of EMPD and cutaneous melanoma have been reported previously. In this case report we present 2 cases of such double cancers: one as a collision tumor, the other at separate sites. We discuss the pathogenesis, treatment, and importance of a thorough clinical and radiological examination and review the literature.

2021 ◽  
pp. 176-183
Author(s):  
Thanachat Rutnumnoi ◽  
Charussri Leeyaphan

Extramammary Paget’s disease (EMPD) is a rare intraepithelial neoplasm that occurs in apocrine-bearing areas of skin. Most EMPD patients initially present with chronic pruritic eczematous lesions involving genitalia, perineum and perianal area. Familial form of EMPD is extremely rare. Several genetic mutations have been proposed but specific modes of inheritance are still unknown. This article reports two cases of familial extramammary Paget’s disease in female siblings.


Skin Cancer ◽  
2020 ◽  
Vol 35 (2) ◽  
pp. 71-75
Author(s):  
Naohisa ICHIKI ◽  
Hirofumi NIWA ◽  
Kanako MATSUYAMA ◽  
Takaaki ITAZU ◽  
Noriyuki NAKAYAMA ◽  
...  

Burns ◽  
2010 ◽  
Vol 36 (8) ◽  
pp. e145-e147 ◽  
Author(s):  
Daofeng Ben ◽  
Liu Liu ◽  
Bing Ma ◽  
Yongyan Li ◽  
Zhaofan Xia

2013 ◽  
Vol 5 (4) ◽  
pp. 171-176
Author(s):  
Slobodan Stojanović ◽  
Nada Vučković ◽  
Pavle Jeremić ◽  
Biljana Jeremić

Abstract The authors present a case of a patient with extramammary Paget’s disease in the pubic region treated by a dermatologist with a private practice for almost 4 years before incisional biopsy was performed. A thorough examination showed no evidence of malignancies of internal organs, whereas definite diagnosis was made by excision of the entire skin lesion and histopathological analysis. With regard to multiple criteria, findings in our patient were consistent with current literature data, but interestingly, the primary extramammary Paget’s disease has not spread into deeper tissues.


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