Efficacy and Safety of Regional Anticoagulation with 4% Trisodium Citrate Versus Heparin in Extended Hemodialysis among Critical Patients with Cancer and Acute Kidney Injury

2020 ◽  
pp. 1-7
Author(s):  
Edwiges Ita De Miranda Moura ◽  
Germana Alves de Brito ◽  
Joubert Araujo Alves ◽  
Marina Harume  Imanishe ◽  
Aline Lourenço Baptista ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Trisodium Citrate ◽  
Efficacy And Safety ◽  
Patients With Cancer ◽  
Critical Patients ◽  
Regional Anticoagulation

scholarly journals Factors Determining Nephrotoxicity and Mortality in Critical Care Patients Receiving Colistin

2018 ◽  
Vol 11 (12) ◽  
pp. 912-917 ◽  
Author(s):  
Ali Ciftci ◽  
Seval Izdes ◽  
Neriman Defne Altintas
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Demographic Data ◽  
Kidney Injury ◽  
Apache Ii ◽  
Factors Affecting ◽  
Acute Kidney Injury Group ◽  
Injury Group ◽  
Independent Risk Factors ◽  
Critical Patients

Introduction: We aimed to determine risk factors for nephrotoxicity and factors affecting mortality in patients who received colistin. Methodology: Critical patients who received colistin were enrolled. Pregnancy, age < 18 years, basal creatinine level > 2 mg/dL, colistin use for < 48 hours, and previous renal replacement therapy were exclusion criteria. KDIGO stages were determined according to creatinine levels. Patients were grouped as those with no acute kidney injury (Group N0) and those with acute kidney injury (Group N). Their demographic data, APACHE II and SOFA scores, treatments, and laboratory results were recorded. Results: A total of 91 patients were included: 27 in Group N0 and 64 in Group N. Demographic data were similar between groups; however, higher admission APACHE-II scores (OR:1.179, 95% CI:1.033-1.346, p = 0.015) and need for vasopressors (OR:5.486, 95% CI:1.522–19.769, p = 0.009) were found to be independent risk factors for nephrotoxicity. Higher APACHE II scores (OR:1.253, %95 CI:1.093-1.437, p = 0.001), presence of coronary artery disease (OR:7.720, % 95 CI: 1.613-36.956, p = 0.011), need for vasopressors (OR: 4.587, % 95 CI: 1.224 – 17.241, p = 0.024), hypoalbuminemia (OR: 4.721, % 95 CI: 1.088 – 20.469, p = 0.038), and higher direct bilirubin levels (OR: 1.806, % 95 CI: 1.055 – 3.092, p = 0.031) were independent risk factors for mortality. Conclusion: When use of colistin is considered in ICU patients, presence of modifiable risk factors for nephrotoxicity such as hypoalbuminemia, nephrotoxic drug administration, and presence of shock should be determined and managed to prevent nephrotoxicity.

Renal support therapy

2021 ◽  
pp. 338-350
Author(s):  
Claudio Ronco ◽  
Stefano Romagnoli ◽  
Zaccaria Ricci
Keyword(s):  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Multiple Organ Failure ◽  
Replacement Therapy ◽  
Kidney Injury ◽  
Multiple Organ ◽  
Acute Illness ◽  
Renal Support Therapy ◽  
Critical Patients ◽  
Renal Support

Renal dysfunction is known to be frequently a component of multiple organ failure, a complex syndrome affecting the most severely ill critical patients. Bidirectional interaction between the kidneys and other organs has always been suspected; evidence suggests that severe kidney injury is an important protagonist in acute illness, even when managed by dialysis. In fact, if it seems that increasing the dose of renal replacement therapy does not reduce mortality, it could be inferred that acute kidney injury influences mortality through means that are not reversed by conventional renal support, either because the putative culprit toxins are not removed by renal replacement therapy or because renal replacement therapy is started too late to prevent these effects. It is known that the kidneys exert effects on other organs, such as the lung, liver, heart, and brain, in a process called 'crosstalk'. This effect means that the kidney is not only a victim, but also a culprit regarding the malfunction of other organs. This chapter will detail some traditional aspects of different renal replacement therapy modalities and prescription schedules, but it will also describe the most recent evidence on the management and support of the kidney during failure of other organs.

Kinetic changes in serum procalcitonin predict persistent acute kidney injury in critical patients

Nephrology ◽  
2021 ◽  
Author(s):  
Kan Shen ◽  
Wei Qu ◽  
Guang‐Kuo Zhao ◽  
Zhi‐Hui Cheng ◽  
Jun Li ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Critical Patients

scholarly journals Metastatic malignancy presenting initially as Acute Kidney Injury: Prospective follow up of six cases

2020 ◽  
Vol 8 (1) ◽  
pp. 29-32
Author(s):  
Tania Mahbub ◽  
Chowdhury Rifat Niger ◽  
Salina Akter ◽  
Rawshan Arra Khanam
Keyword(s):  
Acute Kidney Injury ◽  
Cell Carcinoma ◽  
Kidney Injury ◽  
Interventional Therapy ◽  
Metastatic Carcinoma ◽  
Common Finding ◽  
High Morbidity ◽  
Patients With Cancer ◽  
Carcinoma Of Cervix

Acute kidney injury (AKI) is a significant complication in patients with cancer and is associated with high morbidity and mortality. Rates of AKI vary in cancer patients on the basis of several factors, including types of malignancy (either solid tumor or hematologic), stage of malignancy, associated complications such as critical illness, and type of supportive or interventional therapy given to the patient. AKI is a common finding within the patients diagnosed as malignancy. However, AKI as initial presentation of malignant disease is uncommon. Six cases of metastatic malignancy presenting initially as acute kidney injury are reviewed in this prospective study. We have reviewed one case of metastatic small cell carcinoma of lung, one case of metastatic carcinoma of rectum, one case of metastatic carcinoma, of lung with Horner’s syndrome, one case of metastatic pancreatic carcinoma and one case of metastatic squamous cell carcinoma of cervix. Out of them, two patients needed hemodialysis during hospital stay. Bangladesh Crit Care J March 2020; 8(1): 29-32

Costs and Outcomes of Acute Kidney Injury in Critically Ill Patients with Cancer

2011 ◽  
Vol 9 (4) ◽  
pp. 149-155 ◽  
Author(s):  
Amit Lahoti ◽  
Joseph L. Nates ◽  
Chris D. Wakefield ◽  
Kristen J. Price ◽  
Abdulla K. Salahudeen
Keyword(s):  
Acute Kidney Injury ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Kidney Injury ◽  
Patients With Cancer

Renal Resistive Index and mortality in critical patients with acute kidney injury

2016 ◽  
Vol 46 (3) ◽  
pp. 242-251 ◽  
Author(s):  
Maria Boddi ◽  
Manuela Bonizzoli ◽  
Marco Chiostri ◽  
Dario Begliomini ◽  
Adele Molinaro ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Resistive Index ◽  
Kidney Injury ◽  
Renal Resistive Index ◽  
Critical Patients
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