scholarly journals Heterogeneity of Adult Rhinitis for Multimorbidity and Age at Onset among Non-Sensitized Rhinitis and Mono-/Poly-Sensitized Rhinitis: A Retrospective Cross-Sectional Study

2020 ◽  
Vol 181 (7) ◽  
pp. 512-521
Author(s):  
Jae Won Jeong ◽  
Kyu-Hyoung Lim ◽  
Woo Hyun Lee ◽  
Jun Yeon Won ◽  
Jae-Woo Kwon
Keyword(s):  
Age At Onset ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Admixture analysis of age at onset in older patients with schizophrenia spectrum disorders

2020 ◽  
Vol 32 (6) ◽  
pp. 781-785
Author(s):  
Maureen M. J. Smeets-Janssen ◽  
Idan M. Aderka ◽  
Paul D. Meesters ◽  
Sjors Lange ◽  
Sigfried Schouws ◽  
...  
Keyword(s):  
Late Onset ◽  
Age At Onset ◽  
Cross Sectional Study ◽  
Data Driven ◽  
Admixture Analysis ◽  
Schizophrenia Spectrum Disorders ◽  
Sectional Study ◽  
Cross Sectional ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

ABSTRACTThe nature of schizophrenia spectrum disorders with an onset in middle or late adulthood remains controversial. The aim of our study was to determine in patients aged 60 and older if clinically relevant subtypes based on age at onset can be distinguished, using admixture analysis, a data-driven technique. We conducted a cross-sectional study in 94 patients aged 60 and older with a diagnosis of schizophrenia or schizoaffective disorder. Admixture analysis was used to determine if the distribution of age at onset in this cohort was consistent with one or more populations of origin and to determine cut-offs for age at onset groups, if more than one population could be identified. Results showed that admixture analysis based on age at onset demonstrated only one normally distributed population. Our results suggest that in older schizophrenia patients, early- and late-onset ages form a continuum.

scholarly journals Association between Family Histories of Thyroid Cancer and Thyroid Cancer Incidence: A Cross-Sectional Study Using the Korean Genome and Epidemiology Study Data

Genes ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 1039
Author(s):  
Soo-Hwan Byun ◽  
Chanyang Min ◽  
Hyo-Geun Choi ◽  
Seok-Jin Hong
Keyword(s):  
Thyroid Cancer ◽  
Family History ◽  
Cancer Incidence ◽  
Age At Onset ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Epidemiology Study ◽  
Cross Sectional ◽  
Family Histories ◽  
Thyroid Cancer Incidence

This study assessed the association between thyroid cancer and family history. This cross-sectional study used epidemiological data from the Korean Genome and Epidemiology Study from 2001 to 2013. Among 211,708 participants, 988 were in the thyroid cancer group and 199,588 were in the control group. Trained interviewers questioned the participants to obtain their thyroid cancer history and age at onset. The participants were examined according to their age, sex, monthly household income, obesity, smoking, alcohol consumption, and past medical history. The adjusted odds ratios (95% confidence intervals) for the family histories of fathers, mothers, and siblings were 6.59 (2.05–21.21), 4.76 (2.59–8.74), and 9.53 (6.92–13.11), respectively, and were significant. The results for the subgroup analyses according to sex were consistent. The rate of family histories of thyroid cancer for fathers and siblings were not different according to the thyroid cancer onset, while that of mothers were higher in participants with a younger age at onset (<50 years old group, 11/523 [2.1%], p = 0.007). This study demonstrated that thyroid cancer incidence was associated with thyroid cancer family history. This supports regular examination of individuals with a family history of thyroid cancer to prevent disease progression and ensure early management.

scholarly journals Evidence of a higher prevalence of HPV infection in HTLV-1-infected women: a cross-sectional study

2012 ◽  
Vol 45 (3) ◽  
pp. 305-308 ◽  
Author(s):  
Sônia Sampaio Lôpo ◽  
Paula Matos Oliveira ◽  
Iuri Usêda Santana ◽  
Geisa Barbosa Pena ◽  
Maria Betânia Torrales ◽  
...  
Keyword(s):  
Proviral Load ◽  
Age At Onset ◽  
Hpv Infection ◽  
Cross Sectional Study ◽  
Sexual Life ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group 4 ◽  
School Of Medicine

INTRODUCTION:HTLV-1 infection increases susceptibility to other infections. Few studies have addressed the co-infection between HPV and HTLV-1 and the immune response involved in this interaction. The aim of this study was to determine the prevalence of cervical HPV infection in HTLV-1-infected women and to establish the risk factors involved in this co-infection. METHODS: A cross-sectional study was carried out in Salvador, Brazil, between September 2005 and December 2008, involving 50 HTLV-1-infected women from the HTLV Reference Center and 40 uninfected patients from gynecological clinic, both at the Bahiana School of Medicine. HPV infection was assessed using hybrid capture. HTLV-1 proviral load was quantified using real-time polymerase chain reaction (PCR). RESULTS: The mean age of HTLV-1-infected women (38 ± 10 years) was similar to that of the control group (36 ± 13 years). The prevalence of HPV infection was 44% in the HTLV-1-infected group and 22.5% in uninfected women (p = 0.03). HTLV-1-infected women had lower mean age at onset of sexual life (17 ± 3 years versus 19 ± 3 years; p = 0.03) and greater number of lifetime partners compared with the control group (4 ± 3 versus 2 ± 1; p < 0.01). In the group of HTLV-1-infected patients, there was neither difference in HTLV-1 proviral load between HPV-infected women and the uninfected. CONCLUSIONS: The prevalence of HPV infection was higher in HTLV-1-infected women. Further studies should be performed to evaluate the progression of this co-infection.

scholarly journals Factors Related to Breast Cancer Screening in Women in the Northern Part of Iran: A Cross-Sectional Study

2019 ◽  
Vol 7 (4) ◽  
pp. 637-642 ◽  
Author(s):  
Maryam Kardan-Souraki ◽  
Mahmood Moosazadeh ◽  
Soghra Khani ◽  
Zeinab Hamzehgardeshi
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
Age At Onset ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Educational Method ◽  
Screening Programs ◽  
History Of

BACKGROUND: Breast cancer is the most common type of cancer in women and affects many women around the world each year. Breast cancer screening is one of the best strategies that can be used to reduce the death rate from the disease. Different factors influence the breast cancer screening rate. AIM: This study aimed to investigate the factors that affect the screening of women for breast cancer in the northern part of Iran. MATERIAL AND METHODS: This cross-sectional study was conducted in the Mazandaran Province of Iran in 2016 on 1,165 women who participate in breast cancer screening programs, using a cluster-sampling method. A valid and reliable researcher-made questionnaire was used to collect the data. The collected data were analysed using descriptive and inferential statistics via SPSS 21. RESULTS: In this study, 62% of the women had a history of breast self-examinations, 41.1% had breast examinations by healthcare staff, and 21.7% received mammography. The woman’s age, age at first marriage, age at onset of sexual intercourse, occupation, spouse’s occupation, household income, health status, history of infertility, smoking, and decision-maker on issues of sexual and reproductive health (SRH) were the best predictors of participation in screening for breast cancer (P < 0.05). CONCLUSION: To encourage participation in breast cancer screening programs, women should be encouraged to seek preventive care. Also, factors that affect screening should be considered an appropriate educational method should be provided. ould be considered and appropriate educational methods should be provided.

scholarly journals Early features of autism spectrum disorder: a cross-sectional study

2019 ◽  
Vol 45 (1) ◽  
Author(s):  
Antonia Parmeggiani ◽  
Arianna Corinaldesi ◽  
Annio Posar
Keyword(s):  
Autism Spectrum Disorder ◽  
Intellectual Disability ◽  
Social Interaction ◽  
Age At Onset ◽  
Cross Sectional Study ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Sectional Study ◽  
Cross Sectional ◽  
Early Signs

Abstract Background Autism spectrum disorder is characterized by impairment in social interaction and communication along with repetitive, restricted, and stereotyped behaviors, interests and activities. It is important to detect this condition as soon as possible and promptly begin targeted treatments. This study aimed to report on age at onset, early signs, and mode at onset in 105 Italian patients with autism spectrum disorder, searching for correlations with a series of clinical and instrumental variables. Methods This retrospective cross-sectional study considered the following five categories of symptoms at onset: language, social interaction and relationships, stereotyped behavior and activities, motor skills, and regulation. Three modes of presentation were considered: a delay, a stagnation, or a regression of development, which were defined modes of onset of autism spectrum disorder. The age at onset, the category of clinical features, and the mode at onset were considered in the entire sample and statistically analyzed for several clinical variables. Statistical analysis was performed utilizing Fisher Exact test and Chi Square test. Results The first symptoms between 7 and 12 months were evident in 41.9% of cases, and between 13 and 24 months in 27.6%; no significant differences for the age at onset related to diagnosis, etiopathogenesis, early onset epilepsy, and intelligence quotient level emerged. Social interaction and relationships (93.3%) and language (92.4%) were the categories of early signs more represented in our sample. Delay in spoken language (to be understood as both verbal production and verbal comprehension) was one of the most common (even though not specific) symptoms prompting initial medical consultation for a possible diagnosis of autism spectrum disorder. At onset, patients without intellectual disability manifested stagnation more often than delay or regression of development; patients with a severe/profound intellectual disability more frequently showed delay or regression of development. Language signs at onset were less frequent in cases with regression, whereas motor skill disorders prevailed in cases with delay at onset. Feeding problems were more numerous in cases with delay and stagnation of development. Conclusions These data contribute to identifying an early trend of autism spectrum disorder, useful also for pediatricians.

scholarly journals Childhood Stroke: A Cross-sectional Study in a Tertiary Level Hospital of Bangladesh

2018 ◽  
Vol 6 (1-2) ◽  
pp. 20-24
Author(s):  
Farhana Rahman ◽  
Fauzia Nahid ◽  
Mahmuda Begum ◽  
Nadia Nusrat
Keyword(s):  
Ischemic Stroke ◽  
Acute Stroke ◽  
Age At Onset ◽  
Arterial Occlusion ◽  
Cross Sectional Study ◽  
Hypertensive Encephalopathy ◽  
Sectional Study ◽  
Childhood Stroke ◽  
Cross Sectional ◽  
Clinical Criteria

Background & objective:The present study was undertaken to find the prevalence and pattern of childhood stroke and to see its clinical presentation and sub-types. Materials & Methods:The present cross sectional study was conducted in the Department of Pediatrics, BSMMU, Dhaka over a period of 6 months. A total of 30 children suffering from childhood stroke, provisionally diagnosed on the basis of clinical criteria and confirmed by neuroimaging were the study population.The demographic variables were age, sex, age at onset and age at case taking. The signs and symptoms at presentation, causes, investigations, neuro-imaging findings and final diagnosis were recorded. Result: Over half (53.4%) of the patients were in the range of 13 – 36 months with mean age of the patients being 39.1 ± 8.2 months. The mean age at onset was 36.2 ± 8.3 months. About 47% of patients were male and 53% female. Paresis of limb was invariably present, unconsciousness at onset (50%), convulsion (33.3%), aphasia (26.7%), raised blood pressure (23.3%), vomiting (13.3%), visual defect (8.7%) and headache (6.7%). Arterial occlusion was the main cause of childhood stroke (36.7%) followed by hypertensive encephalopathy (10%), migraine, hematoligical disease, cardiomyopathies (each 6.7%). Investigations revealed that over one-third (36.7%) of the patients had leucocytosis and 13.3% abnormal echocardiography. All the children either exhibited ischemia or infarction or hemorrhage on Computed Tomography (CT) and 86.7% on Magnetic Resonance Imaging (MRI). Seventy percent and 36.7% of patients had MRA and MRV abnormality respectively. About 47% of the patients had acute ischemic stroke, 13.3% AIS with left-sided haemiparesis with facial palsey and another 13.3% AIS with right-sided haemiparesia. Acute haemorragic stroke (AHS), acute stroke with Hb beta-thalassaemia, acute stroke with right-sided haemiparesis with cardiomyopathy and recurrent haemorragic stroke were rare. Conclusion: The study concluded that childhood stroke occurs most frequently between one to three years of age and equally affects male and female. Paresis of limb and unconsciousness at the onset were the main presenting features and arterial hypertension and hypertensive encephalopathy were the common cause of childhood stroke. Nearly three-quarters of the children present with ischemic stroke and the rest with haemorrhagic stroke. Ibrahim Card Med J 2016; 6 (1&2): 20-24

scholarly journals Associations between migraine occurrence and the effect of aura, age at onset, family history, and sex: A cross-sectional study

PLoS ONE ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. e0228284
Author(s):  
Yu-Wei Hsu ◽  
Chih-Sung Liang ◽  
Jiunn-Tay Lee ◽  
Hsuan-Te Chu ◽  
Meei-Shyuan Lee ◽  
...  
Keyword(s):  
Family History ◽  
Age At Onset ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional
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