scholarly journals Exfoliative Erythroderma: An Unusual Presentation of Paraneoplastic Pemphigus Associated with Castleman’s Disease

2020 ◽  
Vol 12 (1) ◽  
pp. 76-82
Author(s):  
Thirawut Sirikham ◽  
Weeratian Tawanwongsri ◽  
Suthinee Rutnin ◽  
Kumutnart Chanprapaph ◽  
Vasanop Vachiramon
Keyword(s):  
Computed Tomography ◽  
Intravenous Immunoglobulin ◽  
Clinical Improvement ◽  
Exploratory Laparotomy ◽  
Unusual Presentation ◽  
Erythematous Rash ◽  
Tumor Removal ◽  
Paraneoplastic Pemphigus ◽  
Complete Tumor Removal ◽  
Complete Tumor

We report a 23-year-old woman who presented with generalized scaly erythematous rash predominately on the upper trunk and hemorrhagic stomatitis. The histopathologic and immunopathologic findings were consistent with the diagnosis of paraneoplastic pemphigus. Castleman’s tumor was diagnosed with computed tomography and exploratory laparotomy. A partial clinical improvement was observed after complete tumor removal and intravenous immunoglobulin administration. However, the patient died as a result of septicemia.

Extraspinal ependymomas

1979 ◽  
Vol 51 (3) ◽  
pp. 383-391 ◽  
Author(s):  
Robert A. Morantz ◽  
John J. Kepes ◽  
Solomon Batnitzky ◽  
Byron J. Masterson
Keyword(s):  
Anterior Approach ◽  
Ependymal Cell ◽  
Review Of The Literature ◽  
Tumor Removal ◽  
Nerve Roots ◽  
Content Type ◽  
The Third ◽  
Complete Tumor Removal ◽  
Pilonidal Cyst ◽  
Complete Tumor

✓ Spinal ependymomas may rarely arise from heterotopic ependymal cell clusters and thus occur in an extraspinal location. Presentation of three cases and a review of the literature reveal that these tumors have characteristic radiographic and clinical features. They occur mainly in patients in the third decade of life, and present either in the soft tissue posterior to the sacrum or in the pelvis. In the case of posterior tumors, the patient exhibits a mass which is usually mistaken for a pilonidal cyst. Patients whose tumor is pelvic in location present with sphincter disturbances or dysfunction of the sacral nerve roots. Conventional and computerized tomographic studies will reveal erosion of the sacrum. Myelography will demonstrate an extradural mass indenting the thecal sac from below. The protein in the cerebrospinal fluid will be normal. A combined posterior and anterior approach with the goal of complete tumor removal is the procedure of choice. If this is not feasible, then radiation therapy should be employed. Because of the increased incidence of systemic metastases, the average postoperative survival is approximately 10 years.

scholarly journals Fluorescein Sodium Use during Spinal Ependymoma Resection

2017 ◽  
Vol 3 (3) ◽  
pp. 123-134
Author(s):  
Zhenxing Sun ◽  
Dan Yuan ◽  
Yaxing Sun ◽  
Zhanquan Zhang ◽  
James Wang ◽  
...  
Keyword(s):  
Removal Rate ◽  
Sensory Function ◽  
Fluorescent Light ◽  
Surgical Removal ◽  
Fluorescein Sodium ◽  
Tumor Removal ◽  
Intramedullary Tumors ◽  
Complete Tumor Removal ◽  
Complete Tumor

Spinal ependymomas (SEs) are common adult intramedullary tumors; however, determining the absolute boundary between the tumor and the tumor residual may be difficult. We assessed outcomes following the use of fluorescein sodium (FS) during surgical removal of SEs. We performed a retrospective analysis of 112 patients with SEs who were treated at Beijing Tsinghua Changgung Hospital between December 2014 and December 2016. Each patient received intravenous FS (3–4 mg/kg) to determine the SE boundaries during surgery. Tumor removal efficiencies and tumor residuals were assessed using magnetic resonance imaging (MRI) at 10 days and 3 months after surgical recovery; McCormick's spinal function classification was also performed at the 3-month follow-up. The complete tumor removal rate was 92% (103/112). Ninety-four patients underwent tumor removal under fluorescent light, which provided distinctive tumor fluorescence. Tumor removal under white light was performed in 18 patients; fluorescent images were invisible or indistinctive in these 18 patients. At the 3-month follow-up, sensory function (85.8% (91/106)) and movement (84.3% (86/102)) were improved in patients with pre-surgical dysfunction; urination and defecation functions were improved in 66.7% (16/24). The McCormick spinal cord functional classifications, at the 3-month follow-up, showed significant differences in the percentages of patients with disease classified to each grade (I–IV), compared with preoperative classifications (each, P < 0.05). There was no MRI evidence of tumor relapse or residuals at the 3-month follow-up. FS use during the surgical treatment of SE enables complete tumor removal and detection of tumor residuals.

Meningioma Involving Meckel's Cave: Transpetrosal Surgical Anatomy and Clinical Considerations

2002 ◽  
Vol 111 (9) ◽  
pp. 850-854 ◽  
Author(s):  
Daniel I. Choo ◽  
David L. Steward ◽  
Myles L. Pensak
Keyword(s):  
Facial Pain ◽  
Skull Base Surgery ◽  
Surgical Anatomy ◽  
Tumor Removal ◽  
Meckel’S Cave ◽  
Complete Tumor Removal ◽  
Meckel's Cave ◽  
Intimate Knowledge ◽  
Clinical Considerations ◽  
Complete Tumor

Meningiomas originating in Meckel's cave (MC) are uncommon lesions that represent 1% of all intracranial meningiomas. Innovations in skull base surgery have enabled resection of these lesions with less morbidity, but require an intimate knowledge of both lesional pathology and regional microneuroanatomy. To review the surgical and clinical considerations involved in the management of MC meningiomas, we retrospectively reviewed data from patients who underwent transpetrosal resection of primary MC meningiomas between 1984 and 1998. Of 146 patients who underwent transpetrosal removal of meningiomas, 7 were believed to have tumors originating in MC. All 7 patients presented with trigeminal dysfunction, facial pain, and/or headache. Complete tumor removal was achieved in 5 of the 7 patients. Facial hypoesthesia or anesthesia, paralysis of cranial nerve VI, and ophthalmoplegia were among the postoperative complications encountered. Meningiomas of MC represent treatable lesions whose diagnosis requires prompt imaging of patients with trigeminal dysfunction and symptoms of facial pain and headache.

Spinal Meningiomas: Review of 174 Operated Cases

Neurosurgery ◽  
1989 ◽  
Vol 25 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Carlo L. Solero ◽  
Maurizio Fornari ◽  
Sergio Giombini ◽  
Giovanni Lasio ◽  
Giuseppe Oliveri ◽  
...  
Keyword(s):  
Neurological Impairment ◽  
Neurological Deficits ◽  
Long Term Results ◽  
Tumor Removal ◽  
Microsurgical Technique ◽  
Complete Tumor Removal ◽  
Spinal Meningiomas ◽  
Subtotal Removal ◽  
Complete Tumor

Abstract The long-term results obtained in a series of 174 patients operated on for spinal meningiomas are critically analyzed. This series was similar to those of other authors with regard to age, sex, location of the tumors, and clinical presentation. Before surgery, about 70% of the patients were included in Groups I and II (mild neurological impairment), and about 30% of the patients were classified in Groups III and IV (significant to severe neurological impairment, up to paraplegia). Complete tumor removal was achieved in 96.5% of the patients, and surgical mortality was about 1%. Microsurgical technique, which was adopted in the last 29 cases, proved to be very effective in reducing undue damage to the spinal cord and in minimizing the postoperative neurological deficits. Of the 174 patients who underwent surgery, 156 underwent late follow-up study for an average of 15 years (2 patients died in the immediate postoperative period, and 16 patients were lost to follow-up). Twenty-nine patients died of causes unrelated to the spinal meningioma; of the remaining 126 patients, 92% were categorized in Groups I and II, and only 8% in Groups III and IV. The rate of recurrence was 6% (9 patients) among the 150 patients who had complete tumor removal, and the rate of regrowth was 17% (1 patient with anaplastic meningioma) among the 6 patients treated by subtotal removal. The early diagnosis of the disease and the use of microsurgical technique appeared as the most relevant factors for further improvement of the surgical results.

scholarly journals Occipital bi-transtentorial/falcine approach for falcotentorial meningioma: case report

2006 ◽  
Vol 64 (1) ◽  
pp. 136-138 ◽  
Author(s):  
Sebastião Gusmão ◽  
Marcelo Magaldi Oliveira ◽  
Aluízio Arantes ◽  
Tales Henrique Ulhoa ◽  
Eric Grossi Morato
Keyword(s):  
Patient Outcome ◽  
Case Report ◽  
Tumor Removal ◽  
Complete Tumor Removal ◽  
Surgical Exposure ◽  
Occipital Transtentorial Approach ◽  
Transtentorial Approach ◽  
Complete Tumor

Lesions located in the bilateral posterior incisural space are difficult to treat due to limited exposure. The classical approaches to this area are limited for lesions located bilaterally and especially when the lesion extends also below the tentorium as it may occur with meningiomas. Kawashima et al. reported, in anatomic studies, a new occipital transtentorial approach: the occipital bi-transtentorial/falcine approach, to treat such lesions. We present a patient with a large falcotentorial meningioma, located bilaterally in the posterior incisural space. The occipital bi-transtentorial/falcine approach allowed an excellent surgical exposure and complete tumor removal with an excellent patient outcome.

Primary polymorphous low-grade adenocarcinoma of the bronchus: Complete tumor removal with bronchoscopic resection

Lung Cancer ◽  
2009 ◽  
Vol 63 (2) ◽  
pp. 301-304 ◽  
Author(s):  
Viboon Boonsarngsuk ◽  
Thitiporn Suwatanapongched ◽  
Mana Rochanawutanon ◽  
Montian Ngodngamthaweesuk ◽  
Piemsak Prakardvudhisarn
Keyword(s):  
Low Grade ◽  
Tumor Removal ◽  
Complete Tumor Removal ◽  
Complete Tumor

Spinal en Plaque Meningiomas: A Contemporary Experience

Neurosurgery ◽  
2004 ◽  
Vol 55 (6) ◽  
pp. 1275-1279 ◽  
Author(s):  
Emanuela Caroli ◽  
Michele Acqui ◽  
Raffaelino Roperto ◽  
Luigi Ferrante ◽  
Giancarlo D'Andrea
Keyword(s):  
Surgical Treatment ◽  
Surgical Removal ◽  
Tumor Removal ◽  
Medline Search ◽  
Complete Tumor Removal ◽  
Spinal Arachnoiditis ◽  
Surgical Cure ◽  
Spinal Meningiomas ◽  
Subtotal Removal ◽  
Complete Tumor

Abstract OBJECTIVE: Spinal en plaque meningiomas are rare and challenging lesions because of their tendency to induce spinal arachnoiditis. The surgical treatment of this type of meningioma is more complex than that of classic meningioma. METHODS: We report seven cases of spinal en plaque meningiomas and review all the cases reported in the literature accessible to us by a MEDLINE search. RESULTS: All patients underwent microsurgery. Complete tumor removal was achieved in three patients. Subtotal removal was performed in four patients. A permanent neurological worsening was observed in one patient. CONCLUSION: Spinal meningiomas en plaque bear a prognosis poorer than that of classic meningiomas with regard to the possibility of a definitive surgical cure because recurrence or postoperative arachnoiditis occurs frequently. Total surgical removal should be attempted only when a clear plane of cleavage between tumor and arachnoid exists.

scholarly journals Endoscopic Endonasal Approach to Pituitary Adenomas

2018 ◽  
Vol 19 (2) ◽  
pp. 54-63
Author(s):  
Paulo Henrique Pires De Aguiar ◽  
Edward R. Laws Junior ◽  
Robert Dodd ◽  
Peter Hwang ◽  
Anne E. Getz
Keyword(s):  
Pituitary Adenomas ◽  
Transsphenoidal Surgery ◽  
Tumor Resection ◽  
Tumor Removal ◽  
Microscopic Method ◽  
Complete Tumor Resection ◽  
Endoscopic Endonasal ◽  
Complete Tumor Removal ◽  
Technical Details ◽  
Complete Tumor

Microscopic transsphenoidal surgery is beyond any doubt a widely accepted and highly effective therapy for pituitary adenomas. Currently several centers have converted to an endoscopic transsphenoidal approach; suggesting that this technique provides more complete tumor resection, better visualization and reduce complications. However, there have been few series to document the results of this procedure. This report presents the technical details and compares it to the results of the microscopic method based on the experience of the group and a literature review. The endoscopic transnasal/ transsphenoidal technique is a safe and effective method for removal of pituitary adenomas. The results found in the literature suggest that the endoscope provides more complete tumor removal, and reduces complications. We believe that the advantages of the endoscopic technique will allow this procedure to become the future gold standard surgical therapy for pituitary adenomas.

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