scholarly journals Cutaneous Malignant Melanoma Metastasis to the Pseudophakic Lens Capsule with Associated Granulomatous Intraocular Inflammation

2020 ◽  
Vol 6 (5) ◽  
pp. 339-343
Author(s):  
Hibba Quhill ◽  
Hardeep S. Mudhar ◽  
Kurt Spiteri Cornish ◽  
Ian G. Rennie
Keyword(s):  
Malignant Melanoma ◽  
Pars Plana Vitrectomy ◽  
Rare Event ◽  
Granulomatous Inflammation ◽  
Cutaneous Malignant Melanoma ◽  
Intraocular Inflammation ◽  
Lens Capsule ◽  
Melanoma Metastasis ◽  
First Case ◽  
Pars Plana

Intraocular cutaneous melanoma metastasis (ICMM) is a rare event, accounting for only 5% of all metastases to the eye and orbit. The vast majority of such metastases primarily affect the choroid and vitreoretinal structures. Only three previous cases of predominant lens structure ICMM have been reported in the literature. Histological examination, in all three past cases, was performed on enucleation specimens of painful blind eyes. We present the first case of ICMM to the lens capsule in a comfortable, seeing, pseudophakic eye. This was histologically confirmed following diagnostic pars plana vitrectomy and capsulotomy, and was found to be associated with background granulomatous intraocular inflammation. The potential causes of the granulomatous inflammation are discussed.

scholarly journals Postprocedural Endophthalmitis or Postprocedural Intraocular Inflammation: A Diagnostic Conundrum

2021 ◽  
pp. 418-424
Author(s):  
Aisha Al Busaidi ◽  
Ahmed Al-Hinai
Keyword(s):  
Pars Plana Vitrectomy ◽  
Povidone Iodine ◽  
Complete Recovery ◽  
Neovascular Glaucoma ◽  
Intraocular Inflammation ◽  
Aqueous Samples ◽  
Patient Counseling ◽  
Pars Plana ◽  
Culture Negative ◽  
Office Procedures

We experienced an atypical endophthalmitis occurring post consecutively performed in-office procedures; an intravitreal injection (IVI) of ranibizumab followed by an anterior chamber (AC) paracentesis performed twice in an eye with neovascular glaucoma (NVG). A 52-year-old diabetic male who was asymptomatic developed signs of endophthalmitis and decreased vision without pain in his left eye a few days post-IVI and AC paracentesis. The condition worsened after an initial vitreous tap and injection of antibiotics. Cultures of vitreous and aqueous samples were negative. Complete resolution occurred after a pars plana vitrectomy with IVI of antibiotics and steroid with removal of a dense “yellowish-brown” fibrinous plaque. The absence of pain, presence of a peculiar colored fibrin, mild-to-moderate vitritis without retinitis, negative cultures, and complete recovery despite the fulminant presentation; favor a diagnosis of inflammation over infection. We hypothesize that a micro-leak from a 26-gauge AC tap tract might have served as an entry port for 5% povidone-iodine from the ocular surface thus inciting inflammation. However, an exuberant inflammatory response that can be typically seen in NVG eyes after intraocular procedures cannot be excluded. Various causes of inflammation post-procedures, both toxic and nontoxic should be considered in atypical culture-negative fulminant endophthalmitis cases with good outcome posttreatment. Any minor ocular procedure may carry a risk of such complication. Patient counseling and care must be exercised in performing these procedures.

scholarly journals First Report of a Case of Ocular Infection Caused by Purpureocillium lilacinum in Poland

Pathogens ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1046
Author(s):  
Robert Kuthan ◽  
Anna K. Kurowska ◽  
Justyna Izdebska ◽  
Jacek P. Szaflik ◽  
Anna Lutyńska ◽  
...  
Keyword(s):  
Contact Lens ◽  
Pars Plana Vitrectomy ◽  
Penetrating Keratoplasty ◽  
Visual Outcome ◽  
Ocular Infection ◽  
Corneal Perforation ◽  
Purpureocillium Lilacinum ◽  
First Case ◽  
Pars Plana ◽  
Tof Ms

This report describes the first case of an ocular infection induced by Purpureocillium lilacinum in Poland. The patient was a 51-year-old immunocompetent contact lens user who suffered from subacute keratitis and progressive granulomatous uveitis. He underwent penetrating keratoplasty for corneal perforation, followed by cataract surgery due to rapid uveitic cataract. A few weeks later, intraocular lens removal and pars plana vitrectomy were necessary due to endophthalmitis. The patient was treated with topical, systemic, and intravitreal voriconazole with improvement; however, the visual outcome was poor. The pathogen was identified by MALDI-TOF MS.

A case of melanoma in a native Australian murid, the spinifex hopping-mouse (Notomys alexis)

2016 ◽  
Vol 38 (1) ◽  
pp. 117 ◽  
Author(s):  
J. M. Old ◽  
M. D. Price
Keyword(s):  
Malignant Melanoma ◽  
Ultraviolet Radiation ◽  
Genetic Predisposition ◽  
Rare Event ◽  
Mammal Fauna ◽  
First Case ◽  
In Captivity ◽  
In The Wild

Generally the reporting of diseases and parasites in Australian native murids is rare despite murids making up ~25% of the native mammal fauna of Australia. This paper reports a malignant melanoma in a captive spinifex hopping-mouse (Notomys alexis) and is the first case of melanoma reported in any native Australian murid. With no exposure to ultraviolet radiation the melanoma is proposed to be the result of genetic predisposition and age. As no other reports have been observed in the colony it is likely to be a very rare event in captivity and unlikely to occur in the wild.

scholarly journals Intravitreal Daptomycin for Recalcitrant Postoperative Endophthalmitis

2016 ◽  
Vol 7 (1) ◽  
pp. 103-107 ◽  
Author(s):  
Jennifer M. Sim ◽  
Kapil G. Kapoor ◽  
Alan L. Wagner
Keyword(s):  
Pars Plana Vitrectomy ◽  
Vancomycin Resistance ◽  
Occurrence Rate ◽  
Postoperative Endophthalmitis ◽  
First Case ◽  
Pars Plana ◽  
Exogenous Endophthalmitis ◽  
Postoperative Findings ◽  
Negative Conclusion ◽  
Culture Negative

Purpose: To report the first case to our knowledge of intravitreal daptomycin used to successfully treat culture-negative vancomycin resistant to exogenous endophthalmitis. Methods: Case report with preoperative, intraoperative, and postoperative findings. Results: A 63-year-old Caucasian male underwent routine pars plana vitrectomy with epiretinal membrane peeling. He developed acute postoperative endophthalmitis, and underwent vitreous tap and injection of intravitreal vancomycin/ceftazidime/dexamethasone. Gram stain showed Gram-positive cocci, but cultures were negative. His infection subsequently proved very recalcitrant and his treatment course involved pars plana vitrectomy with anterior chamber washout and repeat injection of antibiotics, followed by repeat intravitreal vancomycin and ceftazidime. Ultimately, a second vitrectomy with intravitreal daptomycin controlled his intraocular infection. On each occasion, cultures were negative. Conclusion: This case suggests that vancomycin resistance should be considered in culture-negative postoperative endophthalmitis, and intravitreal daptomycin should be considered as an important treatment alternative. Although vancomycin resistance is fairly rare in endophthalmitis, acknowledgment of its increasing occurrence rate is critical for optimal management.

PARS PLANA VITRECTOMY IN THE MANAGEMENT OF INTRAOCULAR INFLAMMATION

1981 ◽  
Vol 59 (5) ◽  
pp. 727-736 ◽  
Author(s):  
P. ALGVERE ◽  
H. ALANKO ◽  
K. DICKHOFF ◽  
Y. LÄHDE ◽  
K. M. SAARI
Keyword(s):  
Pars Plana Vitrectomy ◽  
Intraocular Inflammation ◽  
Pars Plana

Surgical Detachment of the Anterior Hyaloid Membrane From the Posterior Lens Capsule

2017 ◽  
Vol 1 (3) ◽  
pp. 214-217
Author(s):  
Yicheng Chen ◽  
Vaishali Shah ◽  
Abdallah M. Jeroudi ◽  
Kevin J. Blinder ◽  
Gaurav K. Shah
Keyword(s):  
Anterior Chamber ◽  
Salt Solution ◽  
Pars Plana Vitrectomy ◽  
Lens Capsule ◽  
Air Bubbles ◽  
Efficient Removal ◽  
Pars Plana ◽  
Novel Method ◽  
Potential Damage

Purpose: To describe 2 techniques facilitating the potentially challenging removal of the anterior hyaloid during phakic pars plana vitrectomy. Methods: Observational surgical series describing the 2 techniques. The hydrodissection technique applies an injection of balanced salt solution into the anterior chamber to displace the anterior hyaloid posteriorly for facile removal. The bubble technique is a novel method that utilizes air bubbles to visualize the anterior vitreous, allowing closer placement of the vitrectomy cutter to facilitate anterior hyaloid removal. Results: Both techniques were successful for the safe, efficient removal of the anterior vitreous. Conclusion: Removal of the anterior vitreous in a phakic patient is a difficult maneuver which may lead to potential damage to the lens. The hydrodissection and bubble techniques may be used to efficiently and safely remove the anterior vitreous.

scholarly journals Symptomatic bladder metastasis of malignant melanoma: a case report

2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Rahoui Moez ◽  
Mrad Daly Khaireddine ◽  
Wajih Sahnoun ◽  
Alia Zehani ◽  
Mokhtar Bibi ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
English Literature ◽  
Rare Condition ◽  
Cutaneous Malignant Melanoma ◽  
Melanoma Metastasis ◽  
Bladder Metastasis

Abstract Bladder metastasis of cutaneous malignant melanoma is an extremely rare condition, with less than 10 cases reported in the last 30 years in the English literature. Bladder localization is most often asymptomatic, explaining the frequency of cases discovered during autopsy in multi-metastatic patients. We report a case of symptomatic malignant melanoma metastasis to the bladder in a 31-year-old patient.

Pars Plana Vitrectomy for Intraocular Inflammation-related Cystold Macular Edema Unresponsive to Corticosteroids A Preliminary Study

Ophthalmology ◽  
1992 ◽  
Vol 99 (10) ◽  
pp. 1535-1541 ◽  
Author(s):  
Pravin U. Dugel ◽  
Narsing A. Rao ◽  
Serdar Ozler ◽  
Peter E. Liggett ◽  
Ronald E. Smith
Keyword(s):  
Macular Edema ◽  
Pars Plana Vitrectomy ◽  
Intraocular Inflammation ◽  
Pars Plana ◽  
Preliminary Study
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