scholarly journals Amoxicillin-Clavulanate-Induced Ischaemic Colitis

2020 ◽  
Vol 14 (1) ◽  
pp. 242-247 ◽  
Author(s):  
Marco Alonge ◽  
Federica Benini ◽  
Rosanna Cannatelli ◽  
Alessandro Pozzi ◽  
Guido Missale ◽  
...  
Keyword(s):  
Rare Condition ◽  
Screening Tests ◽  
Upper Respiratory Tract ◽  
Ischaemic Colitis ◽  
Drug Induced ◽  
Amoxicillin Clavulanate ◽  
Thrombophilia Screening ◽  
Clostridium Difficile Toxin ◽  
Upper Respiratory ◽  
Stool Cultures

Ischaemic colitis (IC) is the most frequent form of ischaemia of the digestive tract. Due to the worldwide increasing use of medications, there is a growing interest in drug-induced IC. This study reports a rare case of IC directly due to amoxicillin-clavulanate intake. The objective of the study was to describe the evolution of this novel manifestation. An 18-year-old man, non-smoker, with an insignificant medical history, presented with diarrhoea and cramping abdominal pain that started the day following the end of a 10-day amoxicillin-clavulanate course for recent upper respiratory tract infection. Stool cultures including Clostridium difficile toxin testing were negative. Colonoscopy documented an erosive-ulcerative colitis of the sigmoid and the descending colon. Histological examination of the colon biopsies revealed an IC with focal pseudomembranous areas in the descending-sigmoid colon. Thrombophilia screening tests were negative. The patient was discharged from the hospital without symptoms, and another colonoscopy was performed 3 weeks after the previous one, which documented normal endoscopic and histological findings. Amoxicillin-clavulanate IC is a very rare condition and should be suspected once infectious diseases, vascular/haemodynamic causes and a prothrombotic/hypercoagulable state have been excluded. Immediate discontinuation of the antibiotic leads to rapid disease remission.

scholarly journals Complex treatment of diseases of the nasal cavity and paranasal sinuses at the present time

2021 ◽  
pp. 134-139
Author(s):  
V. M. Svistushkin ◽  
K. V. Eremeeva
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Clinical Symptoms ◽  
Local Treatment ◽  
Silver Ions ◽  
Upper Respiratory Tract ◽  
Drug Induced ◽  
High Incidence ◽  
Upper Respiratory ◽  
Pain Symptoms

The search for rational treatment of diseases of the nasal cavity and paranasal sinuses is due to the high incidence among the world's population. Despite the absolutely clear recommendations that would seem to greatly facilitate the choice and scope of therapy, it is extremely important to have a differentiated approach to each patient, depending on age, concomitant pathology, the nature of the course of the disease, the severity of clinical, primarily pain symptoms, and the presence of rhinogenic complications. Differential diagnosis of viral and bacterial acute rhinosinusitis (ARS) allows to avoid unreasonable prescription of antibiotics in the former case and choose therapy in such a way as to help relieve clinical symptoms, timely cure the disease and prevent complications. A systematic review of the literature was conducted with the analysis of scientific research data on the evaluation of the effectiveness of protargol or silver proteinate in the local treatment of upper respiratory tract diseases. A review of studies shows that silver proteinate has astringent, antiseptic and anti-inflammatory effects. The spectrum of antimicrobial action of silver is much wider than many antibiotics and sulfonamides. At the same time, pathogenic microflora is more sensitive to silver ions than non-pathogenic microflora. The analysis of the works also demonstrates the absence of adverse reactions when using this drug. The obtained data allow us to recommend preparations based on silver proteinate as a complex therapy for acute and chronic diseases of the nasal cavity and nasopharynx. The vasoconstrictive effect of protargol allows it to be used as an alternative to decongestants in order to avoid the development of drug-induced rhinitis and tachyphylaxis. Sialor® is a new, convenient, affordable, longer-shelf-life form of silver proteinate.

scholarly journals Conjunctival Lymphangioma: A Case Report and Brief Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Mariana Seca ◽  
Pedro Borges ◽  
Pedro Reimão ◽  
Miguel Gomes ◽  
Angelina Meireles
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Topical Therapy ◽  
Lymphatic Vessels ◽  
Rare Condition ◽  
Upper Respiratory Tract Infection ◽  
Upper Respiratory Tract ◽  
Review Of The Literature ◽  
Upper Respiratory

Background. Lymphangioma is a rare venolymphatic lesion, characterized by dilation of lymphatic vessels. It may occur as an isolated lesion or, more often, represent the surface component of a deep orbital lymphangioma.Case. We report a case of a conjunctival lymphangioma on a 58-year-old male that had simultaneously an upper respiratory tract infection. Excision and biopsy confirmed the nature of the lesion, and there has been no relapse to date.Conclusion. Conjunctival lymphangioma is a rare condition in which the diagnose, must be kept in mind in patients with a red eye resistance to topical therapy and in association with an upper respiratory tract infection. Finally, it is also necessary to be aware of possible recurrence of the lesion.

The study of the upper respiratory tract during drug-induced sleep

2018 ◽  
Vol 26 (3) ◽  
pp. 30 ◽  
Author(s):  
M. Z. Dzhafarova ◽  
V. M. Averbukh ◽  
A. O. Kuznetsov ◽  
Yu. Yu. Rusetsky ◽  
E. N. Latysheva
Keyword(s):  
Respiratory Tract ◽  
Upper Respiratory Tract ◽  
Drug Induced ◽  
Upper Respiratory

scholarly journals TREATMENT OF UPPER RESPIRATORY TRACT INFECTION: A CASE REPORT

2012 ◽  
Vol 2 ◽  
pp. 1
Author(s):  
Sumreen Javed ◽  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Respiratory Tract Infections ◽  
Upper Respiratory Tract Infection ◽  
Upper Respiratory Tract ◽  
Amoxicillin Clavulanate ◽  
Upper Respiratory ◽  
Tract Infections ◽  
Common Infections

Respiratory tract infections are the most common infections in the developing countries. Its mode of spread is also very fast as compared to any other infection. Therefore; we have aimed this study based on the administration of two different drugs, Ciprox (Ciprofloxacin) and Augmentin (amoxicillin/clavulanate potassium), for the treatment of upper respiratory tract infection.

Hypohidrotic ectodermal dysplasia associated with squamous cell carcinoma of the trachea

2002 ◽  
Vol 116 (9) ◽  
pp. 742-743 ◽  
Author(s):  
S. C. A. Winter ◽  
G. J. Bates
Keyword(s):  
Squamous Cell Carcinoma ◽  
Respiratory Tract ◽  
Cell Carcinoma ◽  
Nasal Obstruction ◽  
Squamous Cell ◽  
Ectodermal Dysplasia ◽  
Rare Condition ◽  
Upper Respiratory Tract ◽  
Hypohidrotic Ectodermal Dysplasia ◽  
Upper Respiratory

Hypohidrotic ectodermal dysplasia (HED) is a rare condition characterized by abnormalities to ectodermal derived tissues although other organs or systems are frequently involved. Patients with HED can have a number of symptoms that may lead them to present to the otolaryngologist. We present a case of a 37-year-old female with HED who initially presented with nasal obstruction but then very rapidly developed stridor due to a tracheal squamous cell carcinoma. We suggest a possible association between HED and carcinoma of the upper respiratory tract that has not previously been reported.

scholarly journals β-Lactam Resistance in Upper Respiratory Tract Pathogens Isolated from a Tertiary Hospital in Malaysia

Pathogens ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1602
Author(s):  
Soo Tein Ngoi ◽  
Anis Najwa Muhamad ◽  
Cindy Shuan Ju Teh ◽  
Chun Wie Chong ◽  
Kartini Abdul Jabar ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Tertiary Care ◽  
Tertiary Hospital ◽  
Penicillin G ◽  
Respiratory Pathogens ◽  
Care Hospital ◽  
Upper Respiratory Tract ◽  
Amoxicillin Clavulanate ◽  
Upper Respiratory ◽  
Tract Infections

The rise of antimicrobial resistance (AMR) among clinically important bacteria, including respiratory pathogens, is a growing concern for public health worldwide. Common causative bacteria for upper respiratory tract infections (URTIs) include Streptococcus pneumoniae and Haemophilus influenzae, and sometimes Staphylococcus aureus. We assessed the β-lactam resistant trends and mechanisms of 150 URTI strains isolated in a tertiary care hospital in Kuala Lumpur Malaysia. High rates of non-susceptibility to penicillin G (38%), amoxicillin-clavulanate (48%), imipenem (60%), and meropenem (56%) were observed in S. pneumoniae. Frequent mutations at STMK and SRNVP motifs in PBP1a (41%), SSNT motif in PBP2b (32%), and STMK and LKSG motifs in PBP2x (41%) were observed in S. pneumoniae. H. influenzae remained highly susceptible to most β-lactams, except for ampicillin. Approximately half of the ampicillin non-susceptible H. influenzae harboured PBP3 mutations (56%) and only blaTEM was detected in the ampicillin-resistant strains (47%). Methicillin-susceptible S. aureus (MSSA) strains were mostly resistant to penicillin G (92%), with at least two-fold higher median minimum inhibitory concentrations (MIC) for all penicillin antibiotics (except ticarcillin) compared to S. pneumoniae and H. influenzae. Almost all URTI strains (88–100%) were susceptible to cefcapene and flomoxef. Overall, β-lactam antibiotics except penicillins remained largely effective against URTI pathogens in this region.

A Case of Generalized Wegener's Granulomatosis in Childhood: Successful Therapy With Cyclophosphamide

PEDIATRICS ◽  
1978 ◽  
Vol 61 (2) ◽  
pp. 286-290
Author(s):  
Radhakrishna Baliga ◽  
Chung-Ho Chang ◽  
Anil K. Bidani ◽  
Eugene V. D. Perrin ◽  
Larry E. Fleischmann
Keyword(s):  
Wegener’S Granulomatosis ◽  
Renal Involvement ◽  
Rare Condition ◽  
Wegener's Granulomatosis ◽  
Cytotoxic Agents ◽  
Upper Respiratory Tract ◽  
Pediatric Age Group ◽  
Upper Respiratory ◽  
Tract Infections

An 11-year-old white boy had Wegener's granulomatosis, a rare condition in the pediatric age group. The clinical course, pathological findings, and mode of treatment are outlined. The disease is in remission on a regimen of cyclophosphamide therapy as judged by both clinical and pathological criteria. This syndrome with protean manifestations should be considered in children with symptoms of repeated upper respiratory tract infections along with pulmonary and renal involvement. Early renal biopsy helps to establish the diagnosis of generalized involvement and to guide the course of treatment. Follow-up renal biopsies may serve as an indication for the continuation of treatment. Cytotoxic agents, especially cyclophosphamide, dramatically alter the course of the disease.

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