scholarly journals Myasthenia Gravis with Anti-Muscle-Specific Tyrosine Kinase Antibody during Pregnancy and Risk of Neonatal Myasthenia Gravis: A Case Report and Review of the Literature

2020 ◽  
Vol 12 (1) ◽  
pp. 114-120
Author(s):  
Ken-ichi Inoue ◽  
Jun Tsugawa ◽  
Jiro Fukae ◽  
Kosuke Fukuhara ◽  
Hiroyasu Kawano ◽  
...  
Keyword(s):  
Case Report ◽  
Tyrosine Kinase ◽  
Myasthenia Gravis ◽  
Upper Limb ◽  
High Probability ◽  
Oral Steroid ◽  
Review Of The Literature ◽  
Limb Weakness ◽  
Double Filtration Plasmapheresis ◽  
Double Filtration

A 31-year-old woman presented with a nasal voice, dysarthria, and upper limb weakness during her first pregnancy. Soon after delivery of her first baby, her symptoms disappeared. At the age of 34 years, during her second pregnancy, her nasal voice re-appeared. After delivery of the second baby, her nasal voice worsened, and bilateral eyelid ptosis and easy fatigability were also evident. She was referred to our hospital. Because of her myasthenic symptoms and anti-muscle-specific tyrosine kinase (MuSK) antibody (Ab)-positive status, she was diagnosed as having myasthenia gravis (MG). Her symptoms were worse than those in her first pregnancy. She was treated with oral steroid and double filtration plasmapheresis. After initiation of treatment, her myasthenic symptoms improved completely. In addition, her baby developed transient neonatal MG (TNMG) on the fourth day after birth and then gradually recovered over 30 days. It should be noted that symptoms of patients with anti-MuSK Ab-positive MG (MuSK-MG) can deteriorate during pregnancy, and the babies delivered of patients with MuSK-MG have a high probability of developing TNMG.

Concurrent thyrolipomatosis and thymolipoma in a patient with myasthenia gravis: a case report and review of the literature

2021 ◽  
Vol 103 (7) ◽  
pp. e212-e215
Author(s):  
T Campion ◽  
A Maity ◽  
S Ali ◽  
P Richards ◽  
A Adams
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Clinical Importance ◽  
Imaging Features ◽  
Rare Entity ◽  
Review Of The Literature ◽  
Neck Lump

We present a case of a man with a background of myasthenia gravis who presented with a neck lump, which was diagnosed as thyrolipomatosis in continuity with a very large thymolipoma. Following removal of these lesions, the patient’s myaesthenic symptoms improved. While thymolipomas are often seen in the context of myasthenia gravis, thyrolipomatosis is a rare entity and to our knowledge the concurrent finding of both lesions with myasthenia gravis has never been reported. We highlight the important imaging features of both entities and the clinical importance of recognising them.

Renal failure associated with tyrosine kinase inhibitors—Case report and review of the literature

2010 ◽  
Vol 34 (1) ◽  
pp. 123-127 ◽  
Author(s):  
Anat Gafter-Gvili ◽  
Ron Ram ◽  
Uzi Gafter ◽  
Ofer Shpilberg ◽  
Pia Raanani
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Review Of The Literature

Double filtration plasmapheresis benefits myasthenia gravis patients through an immunomodulatory action

2014 ◽  
Vol 21 (9) ◽  
pp. 1570-1574 ◽  
Author(s):  
Lei Zhang ◽  
Junfeng Liu ◽  
Hongna Wang ◽  
Chongbo Zhao ◽  
Jiahong Lu ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Double Filtration Plasmapheresis ◽  
Immunomodulatory Action ◽  
Double Filtration

Sarcoidosis in a patient with myasthenia gravis. Case report and review of the literature

1991 ◽  
Vol 10 (3) ◽  
pp. 323-325 ◽  
Author(s):  
A. P. Andonopoulos ◽  
P. G. Papathanasopoulos ◽  
C. Karatza ◽  
J. Angelopoulos ◽  
T. Papapetropoulos
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Review Of The Literature

Intrauterine Upper Limb Ischemia Associated with Fetal Thrombophilia: A Case Report and Review of the Literature

2010 ◽  
Vol 124 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Wadah M. Khriesat ◽  
Hala S. Al-Rimawi ◽  
Isam M. Lataifeh ◽  
Suleimman Al-Sweedan ◽  
Eyad Baqain
Keyword(s):  
Case Report ◽  
Upper Limb ◽  
Limb Ischemia ◽  
Review Of The Literature

scholarly journals PROXIMAL BRACHIAL MONOMELIC AMYOTROPHY OR HIRAYAMA DISEASE: NO LONGER AN ALIAS? (case report)

2019 ◽  
Vol 5 (1) ◽  
pp. 5-9
Author(s):  
Akshay Rao
Keyword(s):  
Case Report ◽  
Cervical Spine ◽  
Upper Limb ◽  
Clinical Status ◽  
Supportive Therapy ◽  
Neutral Position ◽  
Mri Findings ◽  
Limb Weakness ◽  
Hirayama Disease ◽  
History Of

Background. Brachial Monomelic Amyotrophy (BMMA) has been called as Hirayama disease (HD) when it is characterized by unilateral distal upper limb weakness and atrophy that shows progression for a limited period and is associated with typical features on MRI of cervical spine in flexion. Objective was to explore the differences when BMMA affects the proximal upper limb muscles with the help of case report. Methods. A case report of BMMA in an adult Indian male is represented. Results. A 30-year-old man presented to us with a history of weakness in the proximal aspect of his left upper limb that began four years ago. The weakness was progressive up until 6 months prior to his presentation since when the weakness had neither worsened nor improved. Cervical spine contrast enhanced MRI revealed mild loss of cervical lordosis, but no features of HD like localized cord atrophy, loss of attachment of dura from subjacent lamina on neutral position axial T2WI MRI, nor any presence of posterior epidural crescentic enhancing mass on flexion contrast sagittal T1WI MRI. The patient was managed with supportive therapy and has been under regular follow up ever since. His clinical status has been stable. Conclusions. We support the suggestion to consider proximal Brachial Monomelic Amyotrophy to be a separate entity and to be distinguished from Hirayama disease that should be reserved for patients with distal upper limb involvement with cervical MRI findings on flexion studies.

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