Apitherapy for Osteoarthritis: Perspectives from Basic Research

2020 ◽  
Vol 27 (3) ◽  
pp. 184-192 ◽  
Author(s):  
Andrés Jagua-Gualdrón ◽  
José Adolfo Peña-Latorre ◽  
Roger Edwin Fernadez-Bernal
Keyword(s):  
Rheumatic Disease ◽  
Royal Jelly ◽  
Basic Research ◽  
The Elderly ◽  
Mechanisms Of Action ◽  
Therapeutic Tool ◽  
Current State ◽  
The World ◽  
Ancient Times ◽  
Therapeutic Alternatives

Osteoarthritis is one of the most common rheumatic disease in the world and one of the leading causes of disability in the elderly. There is still no curative management for the disease, so the search for new therapeutic alternatives continues. ­Apitherapy is a therapeutic tool based on the use of beehive products used since ancient times and, at present, their mechanism of action begins to be known. Many of the mechanisms of action of the beehive products are useful for chronic articular pathophysiological processes such as those described in osteoarthritis. This article presents a review of the current state of understanding of the mechanisms through which bee venom, propolis, honey, pollen, and royal jelly may act on osteoarthritis.

scholarly journals Antioxidant Activity in Bee Products: A Review

Antioxidants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 71
Author(s):  
Marianna Martinello ◽  
Franco Mutinelli
Keyword(s):  
Analytical Methods ◽  
Nutritional Value ◽  
Royal Jelly ◽  
Antioxidant Activities ◽  
Natural Antioxidants ◽  
Bioactive Substances ◽  
Current State ◽  
Wide Range ◽  
Ancient Times ◽  
Antioxidant Characteristics

Bee products have been used since ancient times both for their nutritional value and for a broad spectrum of therapeutic purposes. They are deemed to be a potential source of natural antioxidants that can counteract the effects of oxidative stress underlying the pathogenesis of many diseases. In view of the growing interest in using bioactive substances from natural sources to promote health and reduce the risk of developing certain illnesses, this review aims to update the current state of knowledge on the antioxidant capacity of bee products such as honey, pollen, propolis, beeswax, royal jelly and bee venom, and on the analytical methods used. The complex, variable composition of these products and the multitude of analytical methods used to study their antioxidant activities are responsible for the wide range of results reported by a plethora of available studies. This suggests the need to establish standardized methods to more efficiently evaluate the intrinsic antioxidant characteristics of these products and make the data obtained more comparable.

scholarly journals IN SILICO EVALUATION OF POTASSIUM USNATE

2020 ◽  
Vol 8 (6) ◽  
pp. 524-531
Author(s):  
MARCIO RENNAN SANTOS TAVARES ◽  
VITOR PRATES LORENZO TAVARES ◽  
MATEUS MATIUZZI DA COSTA ◽  
HELINANDO PEQUENO DE OLIVEIRA ◽  
EUGENIA CRISTINA GONCALVES PEREIRA
Keyword(s):  
In Silico ◽  
Mechanisms Of Action ◽  
Screening Tests ◽  
Computer Assisted ◽  
Initial Screening ◽  
Antitumor Activities ◽  
The World ◽  
Approved Drugs ◽  
Viral Components ◽  
Therapeutic Alternatives

A new coronavirus appears in China in December 2019, subsequently threatening the world, it was identified as Covid-19. Its main symptomatic characteristic is directly linked to acute respiratory failure, however there are asymptomatic cases of the disease, mainly in the group not considered at risk. For the treatment of the disease a variety ofantiviral drugs have been tested, with conflicting results. The use of computer-assisted drugs is essential for the development of new therapeutic alternatives for various diseases, once they reduce the time consumed in the initial screening tests, in addition to determining the possible mechanisms of action and reducing toxicity. In our study, we evaluated the interaction of viral components of the coronavirus with potassium usnate, salt derived from lichenic origin and with proven antimicrobial and antitumor activities. Derived from ussic acid, potassium usnate showed low energy for complex formation, this interaction occurs between the usnate salt and the structures of proteinase 3CLpro and enzyme Mpro, all key parts of Covid-19. In addition, in order to prove in silico the use of potassium usnate, they were tested and compared with other approved drugs and candidates for clinical trials to combat the new coronavirus.

Therapeutic fairy tale as a tool supporting educational work of the teacher

2019 ◽  
Vol 577 (2) ◽  
pp. 14-26
Author(s):  
Anna Witkowska-Tomaszewska
Keyword(s):  
Fairy Tales ◽  
Fairy Tale ◽  
Therapeutic Tool ◽  
Educational Work ◽  
Social Competencies ◽  
The World ◽  
Adult World ◽  
Ancient Times ◽  
And Behavior ◽  
Attitudes And Behavior

Use of fairy tales as a therapeutic tool dates back to ancient times because Greeks already used fairy tales as a tool to impact human emotions, attitudes and behavior. By fairy tales, children make a parallel between themselves and the protagonists and through the protagonists’ experiences they develop their own cognitive, emotional or social competencies necessary to deal with specifi c situations in their own lives. Interestingly – as stressed by B. Bettelheim – children select from fairy tales things they are ready for, what they can handle at a given moment, at the level they need. Fairy tales are therefore an important tool for children to learn about the world and I would even say that they are “tools for social and cultural decoding” which help children to get to know and understand the adult world. On the other hand, they are tools that enables adults to discover what is happening in the children’s minds of. Thus, a question arises, what kinds of therapeutic fairy tales exist. How to prepare a fairy tale? How can they be used in everyday educational work? This article presents a method of preparing a therapeutic fairy tale and examples of using fairy tales in educational work with children.

DEVELOPMENT OF THE WORLD MARKET OF SERVICES IN TURBULENCE CONDITIONS AND CHANGES

2017 ◽  
Author(s):  
Larysa Nosach ◽  
◽  
Victoria Morgun ◽  
Keyword(s):  
Economic Development ◽  
International Trade ◽  
Service Sector ◽  
World Market ◽  
Global Dimension ◽  
Trade In Services ◽  
Current State ◽  
The World

The author's research of the current state and features of the development of the world market for services in conditions of turbulence of world processes was carried; the world leaders of the service sector in the global dimension and leaders of the most dynamic articles of service categories were identified; the share of world exports of services by countries by the level of their economic development was justified; weaknesses in the assessment of indicators of international trade in services were identified; the research is based on UNCTAD statistics.

THE EFFECT OF SELF CONFIDENCE, QUALITY EDUCATION AND FAMILY ENVIRONMENT ON INDONESIAN YOUTH IN ENTREPRENEURSHIP

2018 ◽  
Vol 1 (1) ◽  
pp. 29-40
Author(s):  
Novita Novita ◽  
Damar Aji Irawan ◽  
Benyamin Suwitorahardjo
Keyword(s):  
Family Environment ◽  
Research Method ◽  
Basic Research ◽  
Quality Education ◽  
Self Confidence ◽  
Job Opportunities ◽  
The World ◽  
The Future

The biggest challenge faced by students nowadays and in the future, is how to deal with the increasingly high competition in the world, the increasing number of undergraduate and limited job opportunities. In this kind of situations, the students had to find a creative way and change the approach of being a university graduate looking for a job, to become scholars who can create their own jobs, or even able to create jobs for others. The purpose of this study was to determine the youth interest on entrepreneurship in Indonesia. It seems that the youth are unaware to see that the job is increasingly difficult to find nowadays. So through this study, researchers wanted to find out what causes youth in Indonesia, reluctant to become an entrepreneur. While being an entrepreneur, the youth can open or create jobs for others and can reduce the level of unemployment in Indonesia. Self-confidence is an important factor in entrepreneurship. Family environment and quality education also participate in creating interest for youth in entrepreneurship. This research is using basic research method; where researchers will try to link the theories of the existing variables. Thus, researchers can conduct research by distributing questionnaires to the youth throughout Indonesia. This study aims to determine the cause of Indonesian youth lack of interest in entrepreneurship.

Current State and Trends of Export and Import of Fruits and Vegetables in the World

2019 ◽  
pp. 56-63
Author(s):  
Yu.I. Agirbov ◽  
◽  
R.R. Mukhametzyanov ◽  
D.V. Storozhev ◽  
◽  
...  
Keyword(s):  
Fruits And Vegetables ◽  
Current State ◽  
The World

Information Component of Disintegration Processes in Spain and Great Britain: the Comparative Aspects

2019 ◽  
pp. 142-154
Author(s):  
Vasyl Karpo ◽  
Nataliia Nechaieva-Yuriichuk
Keyword(s):  
World War I ◽  
Practical Interest ◽  
Political Influence ◽  
World Politics ◽  
The Political ◽  
Political Actors ◽  
Political Propaganda ◽  
Political Processes ◽  
The World ◽  
Ancient Times

From ancient times till nowadays information plays a key role in the political processes. The beginning of XXI century demonstrated the transformation of global security from military to information, social etc. aspects. The widening of pandemic demonstrated the weaknesses of contemporary authoritarian states and the power of human-oriented states. During the World War I the theoretical and practical interest toward political manipulation and political propaganda grew definitely. After 1918 the situation developed very fast and political propaganda became the part of political influence. XX century entered into the political history as the millennium of propaganda. The collapse of the USSR and socialist system brought power to new political actors. The global architecture of the world has changed. Former Soviet republic got independence and tried to separate from Russia. And Ukraine was between them. The Revolution of Dignity in Ukraine was the start point for a number of processes in world politics. But the most important was the fact that the role and the place of information as the challenge to world security was reevaluated. The further annexation of Crimea, the attempt to legitimize it by the comparing with the referendums in Scotland and Catalonia demonstrated the willingness of Russian Federation to keep its domination in the world. The main difference between the referendums in Scotland and in Catalonia was the way of Russian interference. In 2014 (Scotland) tried to delegitimised the results of Scottish referendum because they were unacceptable for it. But in 2017 we witness the huge interference of Russian powers in Spain internal affairs, first of all in spreading the independence moods in Catalonia. The main conclusion is that the world has to learn some lessons from Scottish and Catalonia cases and to be ready to new challenges in world politics in a format of information threats.

The Indian University in a Comparative Perspective

2018 ◽  
Author(s):  
N.R. Madhava Menon
Keyword(s):  
Higher Education ◽  
Competitive Advantage ◽  
Higher Education Institutions ◽  
Knowledge Society ◽  
Comparative Perspective ◽  
Policy Changes ◽  
University System ◽  
Current State ◽  
The World ◽  
The University

The purpose of looking at Indian universities in a comparative perspective is obviously to locate it among higher education institutions across the world and to identify its strengths and weaknesses in the advancement of learning and research. In doing so, one can discern the directions for reform in order to put the university system in a competitive advantage for an emerging knowledge society. This chapter looks at the current state of universities in India and highlights the initiatives under way for change and proposes required policy changes.

scholarly journals Founding Editorial – Forensics and TheScientificWorld

2001 ◽  
Vol 1 ◽  
pp. 605-608
Author(s):  
Walter Rowe
Keyword(s):  
Forensic Science ◽  
Forensic Toxicology ◽  
Forensic Odontology ◽  
Eyewitness Testimony ◽  
Scientific Application ◽  
Forensic Biology ◽  
Current State ◽  
Tool Mark ◽  
The World ◽  
Forensic Engineering

At the beginning of a new millennium it seems a good idea to stop for a moment and take stock of the current state of forensic science. As a field of scientific research and scientific application, forensic science is a little more than a century old. Forensic science may be said to have begun in 1887 with the simultaneous publication of A. Conan Doyle’s A Study in Scarlet and Hans Gross’s Handbuch für Untersuchungsrichter. Conan Doyle’s novel introduced to the world the character of Sherlock Holmes, whose literary career would popularize the use of physical evidence in criminal investigations. Gross’s manual for examining magistrates suggests ways in which the expertise of chemists, biologists, geologists, and other natural scientists could contribute to investigations. Gross’s book was translated into a number of languages and went through various updated editions during the course of the century. The intervening century saw the development and application of fingerprinting, firearm and tool mark identification, forensic chemistry, forensic biology, forensic toxicology, forensic odontology, forensic pathology, and forensic engineering. Increasingly, the judicial systems of the industrial nations of the world have come to rely upon the expertise of scientists in a variety of disciplines. In most advanced countries, virtually all criminal prosecutions now involve the presentation of scientific testimony. This has had the beneficial effect of diminishing the reliance of courts on eyewitness testimony and defendant confessions.

scholarly journals System models for resilience in gerontology: application to the COVID-19 pandemic

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Katarzyna Klasa ◽  
Stephanie Galaitsi ◽  
Andrew Wister ◽  
Igor Linkov
Keyword(s):  
The Elderly ◽  
System Level ◽  
Improve Quality ◽  
Care Needs ◽  
Individual Level ◽  
Chronic Stressors ◽  
The World ◽  
Aging Adults ◽  
The Individual

AbstractThe care needs for aging adults are increasing burdens on health systems around the world. Efforts minimizing risk to improve quality of life and aging have proven moderately successful, but acute shocks and chronic stressors to an individual’s systemic physical and cognitive functions may accelerate their inevitable degradations. A framework for resilience to the challenges associated with aging is required to complement on-going risk reduction policies, programs and interventions. Studies measuring resilience among the elderly at the individual level have not produced a standard methodology. Moreover, resilience measurements need to incorporate external structural and system-level factors that determine the resources that adults can access while recovering from aging-related adversities. We use the National Academies of Science conceptualization of resilience for natural disasters to frame resilience for aging adults. This enables development of a generalized theory of resilience for different individual and structural contexts and populations, including a specific application to the COVID-19 pandemic.

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