scholarly journals Fungal Endogenous Endophthalmitis Secondary to Magnusiomyces capitatus

2019 ◽  
Vol 10 (2) ◽  
pp. 292-298
Author(s):  
Nestore Rota ◽  
Carla Danese ◽  
Francesca Menchini ◽  
Silvia Pignatto ◽  
Maddalena Peghin ◽  
...  
Keyword(s):  
Single Case ◽  
Immunocompetent Patient ◽  
Ascending Aorta ◽  
Endogenous Endophthalmitis ◽  
Coronary Angiogram ◽  
Literature Research ◽  
Normal Human

We report the case of a 68-year-old immunocompetent patient with a dilatation of the ascending aorta, intraluminal vegetations, and pseudoaneurysmatic bulging who presented with unilateral fungal endogenous endophthalmitis 8 days after coronary angiogram. The isolated pathogen resulted to be Magnusiomyces capitatus, a filamentous, yeast-like fungus that can be commonly found in normal human microflora, with an immunosuppression-related pathogenicity. A literature research revealed a single case of ophthalmic infection – a keratitis – caused by this pathogen. Furthermore, we add a review of mycotic endophthalmitis related to aortic infection.

scholarly journals Aspergillus aortitis in an immunocompetent patient presenting with acute endophthalmitis

2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Joseph M. Rocco ◽  
Maggie K. Benson
Keyword(s):  
Cardiac Surgery ◽  
Early Recognition ◽  
Disease Process ◽  
Infectious Agent ◽  
Immunocompetent Patient ◽  
Endogenous Endophthalmitis ◽  
Laboratory Studies ◽  
Aortic Pseudoaneurysm ◽  
First Case ◽  
Ascending Aortic Pseudoaneurysm

Aspergillus is a common environmental mold most often recognized as an infectious agent in patients with severe immune compromise. We present a case of an immunocompetent patient presenting with endogenous endophthalmitis in the absence of other infectious symptoms. The search for a systemic source revealed an ascending aortic pseudoaneurysm. Surgical resection and pathology revealed angioinvasive aspergillus aortitis. Recent cardiac surgery has been noted to be a risk factor for angioinvasive aspergillosis. Diagnosis is difficult as symptoms are mild and laboratory studies are often normal. To our knowledge this is the first case of aspergillus aortitis presenting as endogenous endophthalmitis without systemic signs of inflammation. These patients have a high mortality rate therefore early recognition is essential. It is important to consider angioinvasive aspergillus infections in patients with prior cardiac surgery presenting with occult embolic phenomena. Only with early diagnosis and prompt treatment can we improve outcomes of this disease process.

Uncommon Association Between Diabetic Ketoacidosis, Thyrotoxicosis, Cutaneous Abscess and Acute Pericarditis in an Immunocompetent Patient: A Single Case Report and Literature Review

2020 ◽  
Vol 16 (6) ◽  
pp. 641-648
Author(s):  
Martinot Amelie ◽  
Demar Magalie ◽  
Thelusme Liliane ◽  
Bounoua Merzaka ◽  
Santa Florin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Case Report ◽  
Diabetic Ketoacidosis ◽  
Metabolic Disorders ◽  
Single Case ◽  
Immunocompetent Patient ◽  
Acute Pericarditis ◽  
Single Case Report

Introduction : The typical factors precipitating diabetic ketoacidosis (DKA) include infections (30%), cessation of antidiabetic medication (20%), and a new diagnosis of diabetes (25%). The etiology remains unknown in 25% of cases. Less frequent causes cited in the literature include severe thyrotoxicosis and, infrequently, pericarditis. Few publications have described the role of human T lymphotropic virus type 1 (HTLV-1) in endocrine and metabolic disorders. Based on a clinical case associated with several endocrine and metabolic disorders, we suggest a potential role for HTLV-1, an endemic virus in the Amazonian area, and review the literature concerning the role of this virus in thyroiditis, pericarditis and diabetes mellitus. Case Report : A fifty-year-old Surinamese woman without any medical history was admitted for diabetic ketoacidosis. No specific anti-pancreatic autoimmunity was observed, and the C-peptide level was low, indicating atypical type-1 diabetes mellitus. DKA was associated with thyrotoxicosis in the context of thyroiditis and complicated by nonbacterial pericarditis and a Staphylococcus aureus subcutaneous abscess. The patient was infected with HTLV-1. Conclusion: To our knowledge, this uncommon association is described for the first time. Few studies have analyzed the implications of HTLV-1 infection in thyroiditis and diabetes mellitus. We did not find any reports describing the association of pericarditis with HTLV-1 infection. Additional studies are necessary to understand the role of HTLV-1 in endocrine and cardiac disorders.

The Structural Error And Its Relation To The Malfunction In Some Abnormal Fibrinogens

1981 ◽  
Author(s):  
A Henschen ◽  
C Southan ◽  
M Kehl ◽  
F Lottspeich
Keyword(s):  
Primary Structure ◽  
Single Case ◽  
Functional Abnormality ◽  
Human Fibrinogen ◽  
Thrombin Cleavage ◽  
Structural Error ◽  
Peptide Release ◽  
Normal Human ◽  
Direct Sequence Analysis ◽  
Function Relationship

The primary structure elucidation of normal human fibrinogen has recently been completed. Thus, it is now possible to analyse the structure- function relationship in detail. In abnormal fibrinogens the function is altered. It is obvious that information about the corresponding structural errors would be of great importance. Functional abnormality of fibrinogen has been described for more than 70 cases. However, only in a single case, Fibrinogen Detroit, the structural error was identified by Blombäck’s group. Recently, our group has analysed several abnormal fibrinogen by separating the three peptide chains and performing direct sequence analysis of the chains. The first fibrinogen (obtained from R. Marx and W. Schramm) had an Arg→Asn substitution in position 19 of the Aa-chain, i.e. in the same position as in Fibrinogen Detroit, and was characterised by delayed A- peptide release and monomer polymerisation. The second fibrinogen (obtained from C. and J. Soria) had an Arg→Cys exchange in position 16 of the Aα- chain, and was characterised by absence of releasable A-peptide. The third fibrinogen (obtained from V. Hofmann) had the same substitution as the previous, but in the heterozygous state, and was characterised by delayed A-peptide release. It is obvious that when the Arg residue in position 16, i.e. at the thrombin cleavage site, is replaced by a neutral residue thrombin will not cleave. When the Arg residue in position 19 is exchanged the cleavage is slowed down. Several other fibrinogens with delayed A-peptide release showed, however, no primary structure error in this section of the molecule.

scholarly journals Bradycardia during Transradial Cardiac Catheterization due to Catheter Manipulation: Resolved by Catheter Removal

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Maheedhar Gedela ◽  
Vishesh Kumar ◽  
Kashif Abbas Shaikh ◽  
Adam Stys ◽  
Tomasz Stys
Keyword(s):  
Heart Rate ◽  
Cardiac Catheterization ◽  
Carotid Sinus ◽  
Stress Test ◽  
Ascending Aorta ◽  
Coronary Angiogram ◽  
First Case ◽  
Brachiocephalic Trunk ◽  
Artery Disease ◽  
The Right

Purpose. To report the resolution of bradycardia encountered during transradial cardiac catheterization through the catheter pullback technique in two cases. Case Report. A 62-year-old male and an 81-year-old male underwent coronary angiogram to evaluate for coronary artery disease and as a result of positive stress test, respectively. Upon engagement of the FL 3.5 catheter into the ascending aorta through the transradial approach, the first case developed bradycardia with a heart rate of 39 beats per minute. The second case developed profound bradycardia with a heart rate of 25 beats per minute upon insertion of the 5 Fr FL 3.5 catheter near the right brachiocephalic trunk through the right radial access. Conclusion. Bradycardia can be subsided by removal of the catheter during catheter manipulation in patients undergoing transradial coronary angiogram if there is a suspicion of excessive stretching of aortic arch receptors and/or carotid sinus receptors.

scholarly journals Incidental Finding of an Aspergillus Pseudoaneurysm in the Ascending Aorta of an Immunocompetent Patient

2021 ◽  
Vol Volume 14 ◽  
pp. 843-847
Author(s):  
Rola Ali ◽  
Abdullah Elhosiny ◽  
Seraj Abualnaja ◽  
Ghassan Baslaim
Keyword(s):  
Incidental Finding ◽  
Immunocompetent Patient ◽  
Ascending Aorta

scholarly journals A cavitary pneumonia caused by leptotrichia species in an immunocompetent patient

2012 ◽  
Vol 4 (1) ◽  
pp. 24 ◽  
Author(s):  
Tze Shien Lo
Keyword(s):  
Immunocompetent Patient ◽  
Immunocompetent Host ◽  
Oral Flora ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus ◽  
Normal Human ◽  
Immunocompromised Hosts

<em>Leptotrichia species </em>(LS) is an anaerobic Gram negative bacillus in the <em>Bacteroidaceae</em> family and part of the normal human oral flora. It is rarely pathogenic, but occasionally causes diseases in immunocompromised hosts. I am reporting a case of cavitary pneumonia caused by LS in an immunocompetent host.

scholarly journals Unilateral Maxillary Sinus Plasmablastic Lymphoma in an Immunocompetent Patient. An Unusual Occurrence Report and Literature Review

2020 ◽  
pp. 014556132096371
Author(s):  
Nayellin Reyes Chicuellar ◽  
Wajiha Sufyan ◽  
Suresh Mahendran
Keyword(s):  
Maxillary Sinus ◽  
Single Case ◽  
Case Reports ◽  
Case Series ◽  
Immunocompetent Patient ◽  
Plasmablastic Lymphoma ◽  
Immunodeficiency Virus ◽  
Unusual Occurrence ◽  
Left Maxillary Sinus ◽  
Hiv Negative

Plasmablastic lymphoma (PBL) is a rare and aggressive form of mature B cell neoplasms almost exclusively identified in patients infected with the human immunodeficiency virus (HIV). The small number of HIV-negative PBL cases reported in the literature to date is composed of single case reports and small case series which characteristically are present involving the oral cavity mucosa or gingiva. We present a 72-year-old HIV-negative Australian patient without any cause of immunodeficiency, with an isolated left maxillary sinus PBL.

Case of endogenous endophthalmitis caused by Klebsiella pneumoniae with magA and rmpA genes in an immunocompetent patient

2013 ◽  
Vol 19 (2) ◽  
pp. 326-329 ◽  
Author(s):  
Akira Sawada ◽  
Shinya Komori ◽  
Kazunari Udo ◽  
Shinsuke Suemori ◽  
Kiyofumi Mochizuki ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Immunocompetent Patient ◽  
Endogenous Endophthalmitis
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