scholarly journals Comparison of Two Different Fibrinogen Concentrates in an in vitro Model of Dilutional Coagulopathy

2019 ◽  
Vol 47 (2) ◽  
pp. 167-174
Author(s):  
Philipp Groene ◽  
Tobias Wiederkehr ◽  
Tobias Kammerer ◽  
Patrick Möhnle ◽  
Melanie Maerte ◽  
...  
Keyword(s):  
In Vitro Model ◽  
Dilutional Coagulopathy ◽  
Vitro Model

Influence of FFP on dilutional coagulopathy - An in vitro model

2008 ◽  
Vol 25 (Sup 44) ◽  
pp. 88
Author(s):  
C. Jambor ◽  
W. Korte ◽  
V. Lesch ◽  
T. Schnider ◽  
G. Kreienbühl
Keyword(s):  
In Vitro Model ◽  
Dilutional Coagulopathy ◽  
Vitro Model

The Effect of Fibrinogen Substitution on Reversal of Dilutional Coagulopathy: An In Vitro Model

2006 ◽  
Vol 102 (2) ◽  
pp. 347-351 ◽  
Author(s):  
Dietmar Fries ◽  
Petra Innerhofer ◽  
Christian Reif ◽  
Werner Streif ◽  
Anton Klingler ◽  
...  
Keyword(s):  
In Vitro Model ◽  
Dilutional Coagulopathy ◽  
Vitro Model

An in vitro model for investigation of vitamin A effects on wound healing

2021 ◽  
pp. 1-6
Author(s):  
Hoda Keshmiri Neghab ◽  
Mohammad Hasan Soheilifar ◽  
Gholamreza Esmaeeli Djavid
Keyword(s):  
Wound Healing ◽  
Endothelial Cell ◽  
Vitamin A ◽  
In Vitro Model ◽  
Cellular Proliferation ◽  
Endothelial Cell Migration ◽  
Normal Fibroblast ◽  
Anti Inflammatory ◽  
Vitro Model

Abstract. Wound healing consists of a series of highly orderly overlapping processes characterized by hemostasis, inflammation, proliferation, and remodeling. Prolongation or interruption in each phase can lead to delayed wound healing or a non-healing chronic wound. Vitamin A is a crucial nutrient that is most beneficial for the health of the skin. The present study was undertaken to determine the effect of vitamin A on regeneration, angiogenesis, and inflammation characteristics in an in vitro model system during wound healing. For this purpose, mouse skin normal fibroblast (L929), human umbilical vein endothelial cell (HUVEC), and monocyte/macrophage-like cell line (RAW 264.7) were considered to evaluate proliferation, angiogenesis, and anti-inflammatory responses, respectively. Vitamin A (0.1–5 μM) increased cellular proliferation of L929 and HUVEC (p < 0.05). Similarly, it stimulated angiogenesis by promoting endothelial cell migration up to approximately 4 fold and interestingly tube formation up to 8.5 fold (p < 0.01). Furthermore, vitamin A treatment was shown to decrease the level of nitric oxide production in a dose-dependent effect (p < 0.05), exhibiting the anti-inflammatory property of vitamin A in accelerating wound healing. These results may reveal the therapeutic potential of vitamin A in diabetic wound healing by stimulating regeneration, angiogenesis, and anti-inflammation responses.

A new in vitro model for pre-transplantation diagnosis of frozen/thawed human ovarian tissue

2011 ◽  
Vol 71 (05) ◽  
Author(s):  
M Salama ◽  
K Winkler ◽  
KF Murach ◽  
S Hofer ◽  
L Wildt ◽  
...  
Keyword(s):  
In Vitro Model ◽  
Ovarian Tissue ◽  
Human Ovarian Tissue ◽  
Vitro Model
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