scholarly journals Eccrine Porocarcinoma on the Lateral Nose Wall: A Rare Case Report

2019 ◽  
Vol 11 (2) ◽  
pp. 215-219
Author(s):  
Kiyoko Fukui ◽  
Masaki Fujioka ◽  
Haruka Matsuo ◽  
Miho Noguchi
Keyword(s):  
Histological Analysis ◽  
Surgical Excision ◽  
Sweat Glands ◽  
Biopsy Specimens ◽  
Cutaneous Tumor ◽  
Rare Case Report ◽  
Receive Treatment ◽  
To Receive ◽  
Eccrine Porocarcinoma ◽  
Eccrine Sweat Glands

Eccrine porocarcinoma (EPC) is an uncommon malignant tumor derived from the eccrine sweat glands. We present a case of EPC on the lateral nose wall, in which the tumor was excised, and the resultant defect was reconstructed using a nasolabial flap. A 66-year-old female was referred to the Department of Plastic and Reconstructive Surgery to receive treatment for a cutaneous tumor on her right lateral nose wall, which had been growing rapidly for 3 months. Histological analysis of a biopsy specimen of the tumor suggested that it was a squamous cell carcinoma. Surgical excision was performed with a 3-mm margin. The tumor was histologically diagnosed as an EPC. EPC exhibits various pathological features; therefore, it is often confused with other malignant cutaneous tumors. We consider that histologically examining surgical specimens obtained via total resection, rather than incisional biopsy specimens, is important for correctly diagnosing EPC.

scholarly journals A Case of Conservatively Managed Invasive Ceruminoma and a Review of the Literature

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
T. F. C. Saunders ◽  
P. Monksfield
Keyword(s):  
Clinical Case ◽  
Histological Analysis ◽  
Surgical Excision ◽  
Sweat Glands ◽  
Review Of The Literature ◽  
Ear Canal ◽  
Clinical Progression ◽  
Rare Tumours ◽  
Local Surgical Excision

Ceruminomas are rare tumours arising from the apocrine sweat glands of the ear canal. We present a case of a malignant ceruminoma, which was managed with local surgical excision only rather than the wider clearance more commonly undertaken with these invasive neoplasms. We present the clinical case, histological analysis, and clinical progression for this patient and review the literature on this uncommon pathology.

scholarly journals An ulcerated exophytic tumour over the gluteal area- eccrine porocarcinoma in an immunocompetent female

2021 ◽  
Vol 8 (5) ◽  
pp. 1600
Author(s):  
Ashok Kumar ◽  
Spandana Jagannath ◽  
Ravi H. Phulware ◽  
Vibhu Mendiratta
Keyword(s):  
Lower Extremity ◽  
Sweat Glands ◽  
Histological Findings ◽  
Rare Type ◽  
Histopathological Studies ◽  
Slow Growing ◽  
Difficult Cases ◽  
Eccrine Porocarcinoma ◽  
Eccrine Sweat Glands ◽  
Growing Mass

Porocarcinoma is a very rare type of skin cancer arising from the eccrine sweat glands and is poorly understood. The exact pathogenesis is unknown. Clinical features are non-specific. It may present as a painless, slow growing mass or nodule, ulcer, plaque, swelling, wart, papule or naevus that increases in size over years to decades and may ulcerate or bleed upon trauma. They occur equally in both sexes and are most commonly found in the lower extremity. Though metastasis is rare, they are considered aggressive with high mortality rate. Diagnosis requires standard histopathological studies. Immunohistochemistry is useful in difficult cases. Treated early, eccrine porocarcinoma is curable by wide excision. The author reports the case of an eccrine porocarcinoma in the lower extremity of an elderly lady and a summary of its clinical, radiological and histological findings is illustrated.

scholarly journals “RARE TUMOUR OF THE HAND: MALIGNANT ACROSPIROMA OF THE HAND“

2020 ◽  
pp. 6-7
Author(s):  
Singh Sandesh Bharat ◽  
Aakansh Jain ◽  
Madhu Kumar ◽  
A .K. Singh
Keyword(s):  
Lymph Node ◽  
Lymph Node Dissection ◽  
Systemic Disease ◽  
Surgical Excision ◽  
Sweat Glands ◽  
Node Dissection ◽  
Rare Tumour ◽  
Case Presentation ◽  
Prophylactic Lymph Node Dissection ◽  
Eccrine Sweat Glands

Background: Malignant acrospiroma is among one of the rare tumors of the eccrine sweat glands. It accounts for around 6% of all malignant eccrine tumors. It typically presents as large ulcerated nodules, and diagnosis can be challenging as it has great overlap with its benign counterpart. There are limited cases reported for hand acrospiroma’s. Case presentation: We report a case of malignant acrospiroma presenting as swelling which was treated with surgical excision. The patient was referred to oncosurgery for chemoradiaton. Conclusion: Wide surgical excision, with or without prophylactic lymph node dissection, is the treatment of choice. Evidence is lacking on the efficacy and/or advised regimen of chemoradiotherapy. Prognosis is poor with systemic disease. More studies are needed for the management of this disease.

scholarly journals Facial Localization of Malignant Chondroid Syringoma: A Rare Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Deniz Tural ◽  
Fatih Selçukbiricik ◽  
Feray Günver ◽  
Abdülkadir Karışmaz ◽  
Süheyla Serdengecti
Keyword(s):  
Head And Neck ◽  
Rare Case ◽  
Sweat Glands ◽  
Benign Tumors ◽  
Chondroid Syringoma ◽  
Rare Case Report ◽  
Trunk Limbs ◽  
The Face ◽  
Mixed Tumors ◽  
Eccrine Sweat Glands

First described by Hirsch and Helwig in 1961, chondroid syringomas (CSs) are rare, benign tumors of the skin arising from the eccrine sweat glands with tumor differentiation in the epithelial and mesenchymal tissues. They most commonly occur in the head and neck, although they may be also found in the axilla, trunk, limbs, and genitalia. The incidence of CS is <0.01% of all primary skin tumors. Malingnant chondroid syringomas (MCS), which are also called malignant mixed tumors of the skin, are extremely uncommon. MCSs commonly involve the limbs and rarely head and neck. In this article, we present a case of malignant chondroid syringoma localized in the face at the left nasolabial region in the light of literature review.

Freeze-Fracture Examination of Tight Junctions of Human Eccrine Sweat Glands

1980 ◽  
Vol 38 ◽  
pp. 634-635
Author(s):  
J. V. Briggman ◽  
J. Bigelow ◽  
H. Bank ◽  
S. S. Spicer
Keyword(s):  
Cystic Fibrosis ◽  
Freeze Fracture ◽  
Sweat Glands ◽  
Hypertonic Solution ◽  
Dark Cells ◽  
Clear Cells ◽  
Junctional Complexes ◽  
Secretory Coil ◽  
Eccrine Sweat Glands ◽  
Eccrine Sweat

The prevalence of strands shown by freeze-fracture in the zonula occludens of junctional complexes is thought to correspond closely with the transepi-thelial electrical resistance and with the tightness of the junction and its obstruction to paracellular flow.1 The complexity of the network of junc¬tional complex strands does not appear invariably related to the degree of tightness of the junction, however, as rabbit ileal junctions have a complex network of strands and are permeable to lanthanum. In human eccrine sweat glands the extent of paracellular relative to transcellular flow remains unknown, both for secretion of the isotonic precursor fluid by the coil and for resorption of a hypertonic solution by the duct. The studies reported here undertook, therefore, to determine with the freeze-fracture technique the complexity of the network of ridges in the junctional complexes between cells in the secretory coil and the sweat ducts. Glands from a patient with cystic fibrosis were also examined because an alteration in junctional strands could underlie the decreased Na+ resorption by sweat ducts in this disease. Freeze-fracture replicas were prepared by standard procedures on isolated coil and duct segments of human sweat glands. Junctional complexes between clear cells, between dark cells and between clear and dark cells on the main lumen, and between clear cells on intercellular canaliculi of the coil con¬tained abundant anastomosing closely spaced strands averaging 6.4 + 0.7 (mean + SE) and 9.0 +0.5 (Fig. 1) per complex, respectively. Thus, the junctions in the intercellular canaliculi of the coil appeared comparable in complexity to those of tight epithlia. Occasional junctions exhibited, in addition, 2 to 5 widely spaced anastomosing strands in a very close network basal to the compact network. The fewer junctional complexes observed thus far between the superficial duct cells consisted on the average of 6 strands arranged in a close network and 1 to 4 underlying strands that lay widely separated from one another (Fig. 2). The duct epitelium would, thus, be judged slightly more "leaky" than the coil. Infrequent junctional complexes observed to date in the secretory coil segment of a cystic fibrosis specimen disclosed rela¬tively few closely crowded strands.

scholarly journals Eccrine Porocarcinoma: A Challenging Diagnostic and Therapeutic Tumoral Entity

2021 ◽  
pp. 700-705
Author(s):  
Ha Mo Linh Le ◽  
Laurence Faugeras ◽  
Véronique De Moor ◽  
Caroline Fervaille ◽  
Thierry Vander Borght ◽  
...  
Keyword(s):  
Skin Lesion ◽  
Fdg Pet ◽  
Wide Local Excision ◽  
Inguinal Node ◽  
Disease Remission ◽  
Cutaneous Tumor ◽  
Case Surgery ◽  
Fdg Pet Scan ◽  
Work Up ◽  
Eccrine Porocarcinoma

Eccrine porocarcinoma is a rare malignant cutaneous tumor with high rates of extracutaneous spread, and its diagnosis and management can be quite challenging. This is a case of an 82-year-old woman presenting with an asymptomatic and chronic pubic skin lesion for whom the work-up required many investigations and procedures to confirm the diagnosis of metastatic eccrine porocarcinoma. Indeed, the patient underwent a wide local excision of the skin lesion, imaging with an FDG-PET scan, a colonoscopy, and two inguinal node dissections. As illustrated in this case, surgery should always be considered to achieve disease remission. Other treatments such as chemotherapy and radiotherapy have also been reported in the literature without clear standard guidelines.

scholarly journals Inflammatory Skin Lesions in Three SARS-CoV-2 Swab-Negative Adolescents: A Possible COVID-19 Sneaky Manifestation?

2021 ◽  
Vol 13 (2) ◽  
pp. 181-188
Author(s):  
Giuseppe Ingravallo ◽  
Francesco Mazzotta ◽  
Leonardo Resta ◽  
Sara Sablone ◽  
Gerardo Cazzato ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Respiratory Symptoms ◽  
Clinical Manifestations ◽  
Skin Lesions ◽  
Sweat Glands ◽  
Histological Findings ◽  
Immune Mediated ◽  
Nodular Lesions ◽  
Immunohistochemical Evidence ◽  
Eccrine Sweat Glands

Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with various clinical manifestations, including skin lesions. In particular, during the COVID-19 pandemic lock-down period numerous chilblain-like lesions, mainly located on the feet, were observed in adolescents. The latter were often asymptomatic or associated with very mild respiratory symptoms. Here, we report three cases of acral nodular lesions in SARS-CoV-2 swab-negative adolescents with histological findings of chronic immune-mediated inflammation and immunohistochemical evidence of SARS-CoV-2 spike glycoproteins in endothelial cells and eccrine sweat glands. In one of these cases, the virus presence was confirmed by electron microscopy.

scholarly journals Resolution of Metastatic Subungal Eccrine Porocarcinoma Treated with Intralesional Interleukin-2

2020 ◽  
Vol 28 (1) ◽  
pp. 220-225
Author(s):  
Ashley Drohan ◽  
Jennifer Melvin ◽  
Joanne Murphy ◽  
Carman Giacomantonio ◽  
Lucy Helyer
Keyword(s):  
Interleukin 2 ◽  
Standard Of Care ◽  
Surgical Excision ◽  
Distant Recurrence ◽  
Unique Case ◽  
Cutaneous Malignancy ◽  
Complete Surgical Excision ◽  
Locally Recurrent ◽  
Eccrine Porocarcinoma

Eccrine porocarcinoma is a rare aggressive cutaneous malignancy. Complete surgical excision is the standard of care, although there are high rates of local and distant recurrence. We present a unique case of locally recurrent and metastatic subungal porocarcinoma successfully treated with intralesional interleukin-2.

Informed Consent in the Military: Fighting a Losing Battle Against the Anthrax Vaccine

2002 ◽  
Vol 28 (2-3) ◽  
pp. 325-343
Author(s):  
Ruth K. Miller
Keyword(s):  
Informed Consent ◽  
Service Member ◽  
Individual Choice ◽  
Civilian Life ◽  
Medical Treatments ◽  
Employment History ◽  
Receive Treatment ◽  
The Right ◽  
The Military ◽  
To Receive

In civilian life, an individual has the right to refuse medical treatment in almost any circumstance. While a patient who refuses treatment may face adverse consequences such as prolonged illness, our society recognizes the importance of individual choice in health matters. Members of the military, however, enjoy no such right. Service members are required to submit to certain medical treatments as a part of their employment contract. Refusing such treatments is disobeying an order, and the service member then faces the prospect of a dishonorable or “other than honorable” discharge, and even imprisonment. Disobeying an order to receive treatment can thus result in the equivalent of a felony conviction on the individual's employment history forever.

scholarly journals Training of Eccrine Sweat Glands in Paraplegics

1970 ◽  
Vol 54 (3) ◽  
pp. 229-232 ◽  
Author(s):  
Becky B. Johnson ◽  
Robert E. Johnson
Keyword(s):  
Sweat Glands ◽  
Eccrine Sweat Glands ◽  
Eccrine Sweat
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