scholarly journals A Case of Miscarriage Caused by a Small Uterus following Childhood Chemotherapy

2019 ◽  
Vol 12 (2) ◽  
pp. 443-446
Author(s):  
Rie Kitayama
Keyword(s):  
Acute Lymphocytic Leukemia ◽  
Hormone Replacement ◽  
Lower Abdominal Pain ◽  
Lymphocytic Leukemia ◽  
Frozen Embryos ◽  
Gestational Week ◽  
In Pregnancy ◽  
Hormone Replacement Cycle ◽  
Spontaneous Delivery

A majority of miscarriages have been thought to be caused by fertile ovum abnormalities; however, our findings suggest that a small uterus can also potentially cause miscarriage. There are no reports on the association between a small uterus and miscarriage. A woman in her late 20s, whose medical history revealed childhood acute lymphocytic leukemia, which progressed to remission after chemotherapy, radiotherapy, and bone marrow transplantation. Ultrasound revealed no ovarian follicles in either of the ovaries and small uterus (length, 32 mm) In cycle 15, after ovum collection, frozen embryos with Veeck’s classification of G3b9 were obtained. Embryo transplantation was performed during the hormone replacement cycle, resulting in pregnancy. On day 5 of gestational week 18, the patient experienced mild lower abdominal pain, and she underwent a spontaneous delivery.

scholarly journals Immunologic classification of childhood acute lymphocytic leukemia

Cancer ◽  
1981 ◽  
Vol 47 (2) ◽  
pp. 280-284 ◽  
Author(s):  
Kenneth A. Foon ◽  
Philip Herzog ◽  
Ronald J. Billing ◽  
Paul I. Terasaki ◽  
Stephen A. Feig
Keyword(s):  
Acute Lymphocytic Leukemia ◽  
Lymphocytic Leukemia

Detection and Classification of Acute Lymphocytic Leukemia

2020 ◽  
Author(s):  
Pradeep Kumar Das ◽  
Priyanka Jadoun ◽  
Sukadev Meher
Keyword(s):  
Acute Lymphocytic Leukemia ◽  
Lymphocytic Leukemia

B cell acute lymphocytic leukemia in pregnancy

2010 ◽  
Vol 284 (2) ◽  
pp. 303-306 ◽  
Author(s):  
Justin Bottsford-Miller ◽  
Sina Haeri ◽  
Arthur M. Baker ◽  
Jeremiah Boles ◽  
Mark Brown
Keyword(s):  
B Cell ◽  
Acute Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
In Pregnancy

Motility of leukemic lymphocytes

1990 ◽  
Vol 48 (3) ◽  
pp. 368-369
Author(s):  
Manoj Raje ◽  
Karvita B. Ahluwalia
Keyword(s):  
Quantitative Data ◽  
Laser Doppler Velocimetry ◽  
Acute Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Cellular Space ◽  
Differentiated Cells ◽  
Poorly Differentiated ◽  
Solid Tissues ◽  
Well Differentiated ◽  
Reduced Mobility

In Acute Lymphocytic Leukemia motility of lymphocytes is associated with dissemination of malignancy and establishment of metastatic foci. Normal and leukemic lymphocytes in circulation reach solid tissues where due to in adequate perfusion some cells get trapped among tissue spaces. Although normal lymphocytes reenter into circulation leukemic lymphocytes are thought to remain entrapped owing to reduced mobility and form secondary metastasis. Cell surface, transmembrane interactions, cytoskeleton and level of cell differentiation are implicated in lymphocyte mobility. An attempt has been made to correlate ultrastructural information with quantitative data obtained by Laser Doppler Velocimetry (LDV). TEM of normal & leukemic lymphocytes revealed heterogeneity in cell populations ranging from well differentiated (Fig. 1) to poorly differentiated cells (Fig. 2). Unlike other cells, surface extensions in differentiated lymphocytes appear to originate by extrusion of large vesicles in to extra cellular space (Fig. 3). This results in persistent unevenness on lymphocyte surface which occurs due to a phenomenon different from that producing surface extensions in other cells.

Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia

2001 ◽  
Vol 2 (2) ◽  
pp. 103-107 ◽  
Author(s):  
Simone Boehrer ◽  
Kai U Chow ◽  
Elena Puccetti ◽  
Martin Ruthardt ◽  
Shahrzad Godzisard ◽  
...  
Keyword(s):  
Acute Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Response Gene ◽  
Gene 4

New Therapeutic Approach to Reduce Methotrexate Toxicity after High-Dose Chemotherapy in a Child with Acute Lymphocytic Leukemia: Efficacy and Safety of Hemoadsorption with HA-230 Adsorber

2021 ◽  
pp. 1-5
Author(s):  
Vitaliy Sazonov ◽  
Zaure Tobylbayeva ◽  
Askhat Saparov ◽  
Bolatbek Jubaniyazov ◽  
Samat Issakov ◽  
...  
Keyword(s):  
Acute Lymphocytic Leukemia ◽  
Pediatric Patients ◽  
High Dose Chemotherapy ◽  
The Body ◽  
Lymphocytic Leukemia ◽  
High Dose ◽  
Successful Implementation ◽  
Efficacy And Safety ◽  
Related Complication ◽  
Dose Methotrexate

Background: High-dose methotrexate (HDMTX) is likely to cause a number of side effects and manifest itself as hepatotoxicity, nephrotoxicity, mucositis, and neurotoxicity. A several studies demonstrated the efficacy of extracorporeal detoxification methods such as plasma exchange, hemodialysis (HD), HD filtration, and hemoperfusion for the treatment of MTX delayed clearance. However, none of the existing methods as effective as expected and limited for general implementation due to a procedure-related complication. Case Report: Here, we report a successful implementation of HA-230 hemoadsorption procedure to remove cumulated MTX from the body and reduce its toxicity in a child with ALL after high-dose chemotherapy. Results and Conclusion: Based on our results, single-hemoadsorption procedure with the HA-230 adsorber in case of delayed methotrexate clearance was safe and well-tolerated in a pediatric patient with ALL and would significantly improve the patient’s condition. Further studies need to demonstrate its safety and efficacy in a large number of pediatric patients.

Severe Oral Mucositis in a Patient With Acute Lymphocytic Leukemia: Case Report

2014 ◽  
Vol 117 (2) ◽  
pp. e189
Author(s):  
JEFFERSON FREIRE CARDOSO ◽  
REBEKA THIARA NASCIMENTO DOS SANTOS ◽  
CÉLIA MARIA BOLOGNESE FERREIRA ◽  
JECONIAS CAMARA ◽  
TATIANA NAYARA LIBORIO
Keyword(s):  
Case Report ◽  
Oral Mucositis ◽  
Acute Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Severe Oral Mucositis
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