scholarly journals Vibrio parahaemolyticus Induced Cellulitis and Septic Shock after a Sea Beach Holiday in a Patient with Leg Ulcers

2019 ◽  
Vol 11 (1) ◽  
pp. 94-100 ◽  
Author(s):  
Caroline Guillod ◽  
Francesca Ghitti ◽  
Carlo Mainetti
Keyword(s):  
Septic Shock ◽  
Lower Limb ◽  
Vibrio Parahaemolyticus ◽  
Salt Water ◽  
Clinical Manifestations ◽  
Leg Ulcers ◽  
Negative Bacterium ◽  
Gram Negative

Infections with Vibrio parahaemolyticus, a gram-negative bacterium found in salt water, are mainly gastrointestinal or cutaneous. The development of sepsis is not uncommon. We report the case of an 85-year-old patient who developed lower limb cellulitis caused by V. parahaemolyticus, originating from leg ulcers and complicated by septicaemia and septic shock, after a sea beach holiday. We discuss the epidemiology, pathogenesis, clinical manifestations and treatment of V. parahaemolyticus infections.

scholarly journals A Case of Fatal Meliodosis presenting as Septic Arthritis and Septicaemia

2015 ◽  
Vol 3 (2) ◽  
pp. 74-76 ◽  
Author(s):  
Kaniz Fatema ◽  
ASM Areef Ahsan ◽  
Lovely Barai ◽  
Debasish Kumar Saha ◽  
Samira Rahat Afroze ◽  
...  
Keyword(s):  
Septic Shock ◽  
Synovial Fluid ◽  
Septic Arthritis ◽  
Burkholderia Pseudomallei ◽  
Clinical Manifestations ◽  
Middle Aged ◽  
Gram Negative

Meliodosis, caused by the gram negative saprophyte Burkholderia pseudomallei, is very difficult to diagnose clinically because of varied presentations and lack of awareness. It causes various clinical manifestations like pneumonia, septicaemia, septic shock, septic arthritis, abscesses in different organs etc. The organism can be difficult to identify in laboratories with little experience of B pseudomallei. For effective and timely initiated treatment, clinicians and microbiologists should communicate with each other. Here we report a case of a middle aged diabetic lady who presented with septic arthritis. Burkholderia pseudomallei was isolated from blood and synovial fluid cultures. The unfortunate woman succumbed to death from septic shock before diagnosis.Bangladesh Crit Care J September 2015; 3 (2): 74-76

scholarly journals Genome sequence of Vibrio sp. OULL4 isolated from shellfish

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Vengadesh Letchumanan ◽  
Wen-Si Tan ◽  
Wai-Fong Yin ◽  
Kok-Gan Chan
Keyword(s):  
Vibrio Cholerae ◽  
Genome Sequence ◽  
Vibrio Parahaemolyticus ◽  
Vibrio Vulnificus ◽  
Diverse Group ◽  
Seafood Consumption ◽  
Negative Bacterium ◽  
Antibiotic Resistant ◽  
Gram Negative ◽  
Resistant Strains

The members of Vibrionaceae family are Gram-negative bacterium are ubiquitous in marine and estuarine environments. This diverse group of bacteria include many pathogenic strains that potentially cause infection to humanand aquaculture animals. Vibrio cholerae, Vibrio parahaemolyticus and Vibrio vulnificus are among the few recognized as a major, worldwide cause gastroenteritis, particularly in countries where seafood consumption is high. The control of these vibrios has been a hurdle due to the rising numbers of antibiotic resistant strains in the environments. We report the genome sequence of Vibrio sp. OULL4 isolated from shellfish. The availability of this genome sequence will facilitate the study of its antimicrobial traits, as well as add our knowledge of Vibrio sp. diversity and evolution.

scholarly journals Tularemia Goes West: Epidemiology of an Emerging Infection in Austria

2020 ◽  
Vol 8 (10) ◽  
pp. 1597 ◽  
Author(s):  
Stefanie Seiwald ◽  
Anja Simeon ◽  
Erwin Hofer ◽  
Günter Weiss ◽  
Rosa Bellmann-Weiler
Keyword(s):  
Infectious Disease ◽  
Differential Diagnosis ◽  
Francisella Tularensis ◽  
Clinical Manifestations ◽  
Zoonotic Disease ◽  
Public Institutions ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Potential Host ◽  
Emerging Infection

The zoonotic disease tularemia is caused by the Gram-negative bacterium Francisella tularensis, with the two major subspecies tularensis and holarctica being responsible for infections in humans and animals. The F. tularensis subspecies holarctica is less virulent and prevalent in Europe and Asia. Over the last few centuries, few epidemic outbreaks and low numbers of infections have been registered in the eastern part of Austria, specifically in the provinces of Lower Austria, Burgenland, and Styria. The reported infections were mostly associated with hunting hares and the skinning of carcasses. Within the last decade, ticks have been identified as important vectors in Tyrol and served as first evidence for the spread of F. tularensis to Western Austria. In 2018, the pathogen was detected in hares in the provinces of Tyrol, Vorarlberg, and Salzburg. We presume that F. tularensis is now established in most regions of Austria, and that the investigation of potential host and vector animals should be spotlighted by public institutions. Tularemia in humans presents with various clinical manifestations. As glandular, ulceroglandular, and typhoidal forms occur in Austria, this infectious disease should be considered as a differential diagnosis of unknown fever.

scholarly journals Rolipram Protects Mice from Gram-negative Bacterium Escherichia coli-induced Inflammation and Septic Shock

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Xiaying Lu ◽  
Juan Wang ◽  
Xiaohuan Chen ◽  
Yong Jiang ◽  
Zhixing K. Pan
Keyword(s):  
Escherichia Coli ◽  
Septic Shock ◽  
Negative Bacterium ◽  
Gram Negative

scholarly journals Massiliamide, a cyclic tetrapeptide with potent tyrosinase inhibitory properties from the Gram-negative bacterium Massilia albidiflava DSM 17472T

2020 ◽  
Author(s):  
Andri Frediansyah ◽  
Jan Straetener ◽  
Heike Brötz-Oesterhelt ◽  
Harald Gross
Keyword(s):  
Absolute Configuration ◽  
Inhibitory Activity ◽  
Liquid Culture ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Negative Bacterium ◽  
Gram Negative ◽  
The Absolute ◽  
Potent Inhibitory Activity ◽  
Cyclic Tetrapeptide

AbstractA cyclic tetrapeptide, designated massiliamide, was isolated from the liquid culture of the Gram-negative bacterium Massilia albidiflava DSM 17472T. The structure was elucidated through extensive spectroscopic analysis, including HR-MS and 1D and 2D NMR experiments. The absolute configuration was determined using the Marfey´s method. Massiliamide showed potent inhibitory activity towards tyrosinase with an IC50 value of 1.15 µM and no cytotoxicity.

scholarly journals Septic shock due to Yersinia pseudotuberculosis infection in an adult immunocompetent patient: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Takehiro Hashimoto ◽  
Ryuichi Takenaka ◽  
Haruka Fukuda ◽  
Kazuhiko Hashinaga ◽  
Shin-ichi Nureki ◽  
...  
Keyword(s):  
Septic Shock ◽  
Therapeutic Strategy ◽  
Yersinia Pseudotuberculosis ◽  
Immunocompromised Host ◽  
Immunocompetent Patient ◽  
Case Presentation ◽  
Gram Negative ◽  
Old Japanese ◽  
The Right ◽  
Immunocompetent Patients

Abstract Background Yersinia pseudotuberculosis infection can occur in an immunocompromised host. Although rare, bacteremia due to Y. pseudotuberculosis may also occur in immunocompetent hosts. The prognosis and therapeutic strategy, especially for immunocompetent patients with Y. pseudotuberculosis bacteremia, however, remains unknown. Case presentation A 38-year-old Japanese man with a mood disorder presented to our hospital with fever and diarrhea. Chest computed tomography revealed consolidation in the right upper lobe with air bronchograms. He was diagnosed with pneumonia, and treatment with intravenous ceftriaxone and azithromycin was initiated. The ceftriaxone was replaced with doripenem and the azithromycin was discontinued following the detection of Gram-negative rod bacteria in 2 sets of blood culture tests. The isolated Gram-negative rod bacteria were confirmed to be Y. pseudotuberculosis. Thereafter, he developed septic shock. Doripenem was switched to cefmetazole, which was continued for 14 days. He recovered without relapse. Conclusions We herein report a case of septic shock due to Y. pseudotuberculosis infection in an adult immunocompetent patient. The appropriate microorganism tests and antibiotic therapy are necessary to treat patients with Y. pseudotuberculosis bacteremia.

scholarly journals Porphyromonas gingivalis fimbrial protein Mfa5 contains a von Willebrand factor domain and an intramolecular isopeptide

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Thomas V. Heidler ◽  
Karin Ernits ◽  
Agnieszka Ziolkowska ◽  
Rolf Claesson ◽  
Karina Persson
Keyword(s):  
Porphyromonas Gingivalis ◽  
Von Willebrand Factor ◽  
Host Cells ◽  
Negative Bacterium ◽  
Oral Biofilm ◽  
Gram Negative ◽  
Type V ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Fimbrial Protein

AbstractThe Gram-negative bacterium Porphyromonas gingivalis is a secondary colonizer of the oral biofilm and is involved in the onset and progression of periodontitis. Its fimbriae, of type-V, are important for attachment to other microorganisms in the biofilm and for adhesion to host cells. The fimbriae are assembled from five proteins encoded by the mfa1 operon, of which Mfa5 is one of the ancillary tip proteins. Here we report the X-ray structure of the N-terminal half of Mfa5, which reveals a von Willebrand factor domain and two IgG-like domains. One of the IgG-like domains is stabilized by an intramolecular isopeptide bond, which is the first such bond observed in a Gram-negative bacterium. These features make Mfa5 structurally more related to streptococcal adhesins than to the other P. gingivalis Mfa proteins. The structure reported here indicates that horizontal gene transfer has occurred among the bacteria within the oral biofilm.

scholarly journals Anion inhibition studies of the Zn(II)-bound ι-carbonic anhydrase from the Gram-negative bacterium Burkholderia territorii

2021 ◽  
Vol 36 (1) ◽  
pp. 372-376
Author(s):  
Andrea Petreni ◽  
Viviana De Luca ◽  
Andrea Scaloni ◽  
Alessio Nocentini ◽  
Clemente Capasso ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Inhibition Studies

The structure of the O-polysaccharide isolated from pectinolytic gram-negative bacterium Dickeya aquatica IFB0154 is different from the O-polysaccharides of other Dickeya species

2020 ◽  
Vol 497 ◽  
pp. 108135
Author(s):  
Agnieszka Kowalczyk ◽  
Nikola Szpakowska ◽  
Wojciech Sledz ◽  
Agata Motyka-Pomagruk ◽  
Karolina Ossowska ◽  
...  
Keyword(s):  
Negative Bacterium ◽  
Gram Negative
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