scholarly journals Efficacy of Mucosal Cutting Biopsy for the Histopathological Diagnosis of Gastric Submucosal Tumors

2019 ◽  
Vol 13 (1) ◽  
pp. 185-194 ◽  
Author(s):  
Akihisa Adachi ◽  
Yoshikazu Hirata ◽  
Hayato Kawamura ◽  
Takahito Harada ◽  
Reika Hattori ◽  
...  

Background: Gastrointestinal stromal tumors occur frequently. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is performed commonly for diagnosis. However, the success rate of histological diagnosis is insufficient when the submucosal tumor (SMT) is small. Recently, another technique, mucosal cutting biopsy (MCB) has been reported. The aim of this study is to evaluate the efficacy and safety of MCB. Method: Between January 2012 and August 2018, MCB and EUS-FNA were performed 16 and 31 times for diagnosing gastric SMT. The diagnostic rate, the rate of successful immunohistochemistry, and the safety were reviewed. Difficult locations for EUS-FNA were also evaluated. Results: The mean SMT sizes measured on MCB and EUS-FNA were 21.2 and 36.2 mm. The diagnostic rates of MCB and EUS-FNA were almost the same (88 vs. 81%), but successful immunohistochemistry was significantly higher in the MCB group (93 vs. 59%, p = 0.03). In the subgroup of SMTs < 20 mm, the successful histological diagnosis rate from EUS-FNA was relatively low. There were no complications. Failures of EUS-FNA were more frequent in the middle third of the stomach. Conclusions: MCB was an effective procedure for diagnosing gastric SMT, especially in the case of small SMTs located at the middle third of the stomach.

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 4574-4574
Author(s):  
A. Sawaki ◽  
N. Mizuno ◽  
N. Hoki ◽  
T. Takagi ◽  
T. Nakamura ◽  
...  

CytoJournal ◽  
2014 ◽  
Vol 11 ◽  
pp. 19 ◽  
Author(s):  
Emad Raddaoui ◽  
Esam H Alhamad ◽  
Shaesta Naseem Zaidi ◽  
Fatmah F Al-Habeeb ◽  
Maha Arafah

Objective: The objective of this study is to evaluate the cytological accuracy of endobronchial ultrasound-guided transbronchial fine-needle aspiration (EBUS-TFNA) of the mediastinal mass/nodular lesions. Study Design: Over 3½ years from inception at King Khalid University Hospital, a retrospective analysis of the cytological diagnoses of all the EBUS-TFNA procedures performed in 80 patients who had mediastinal mass/nodular enlargement. Cytology results were reviewed and correlated with the histologic follow-up. Results: Of the 80 patients who underwent EBUS-TFNA, 15 cases (18.75%) were positive for malignancy, 48 cases (60%) negative for malignancy and 17 cases (21.25%) unsatisfactory. Of the 48 cases, which were negative for malignancy, 24 (50%) cases were of granulomatous inflammation. The overall diagnostic yield of our EBUS-TFNA specimen was 78.75%. Forty-seven cases (58.75%) of 80 cases had histological follow-up biopsies. Among them, 32 cases (68%) had the same cytological and histological diagnosis and 15 cases (31.09%) had discordance between the cytology and the follow-up histological diagnosis. The sensitivity, specificity, and positive and negative predictive values for diagnosing granulomas by EBUS-TFNA are 77%, 82%, 83%, and 75% and for diagnosing malignancy are 71%, 100%, 100%, and 82%, respectively. Conclusion: Preliminary results show that cytological samples obtained through EBUS-TFNA are accurate and specific in making a diagnosis of the mediastinal mass/nodular lesions. Its optimum use depends on the effective collaboration between the cytotechnologist, pathologist, and the bronchoscopist.


Endoscopy ◽  
2015 ◽  
Vol 47 (S 01) ◽  
pp. E69-E70
Author(s):  
Hiroshi Kawakami ◽  
Masaki Kuwatani ◽  
Kimitoshi Kubo ◽  
Yoshimasa Kubota ◽  
Kazumichi Kawakubo ◽  
...  

2020 ◽  
Vol 10 (7) ◽  
pp. 1570-1574
Author(s):  
Xiangyu Liu ◽  
Xiaogang Ren ◽  
Xiaoying Ma ◽  
Xi Sun ◽  
Yue Wu ◽  
...  

To explore the clinical features and endosonographic (EUS) features of gastric submucosal tumors, the connection of submucosal tumor features and pathological features are analyzed to increase the awareness of submucosal tumors. This study is based on 237 cases of gastric mucosal lesions from March 2015 to March 2019. Endoscopic ultrasonography was performed to record the size and origin of the lesions and to make the preliminary qualitative diagnosis of the lesions, where endoscopic resections have 186 cases. According to the actual lesion resection in endoscopic ultrasonography, the origin level of SMTs and the coincidence rate of endoscopic ultrasonography diagnoses are judged. Therefore, endoscopic ultrasonography has high localization, characterization, and differential diagnosis value for gastric mucosal lesions. Diagnosis of gastric mucosal lesions under endoscopic ultrasonography is helpful for the choice of endoscopic resection surgical method.


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