Effect of EP1 Receptor Antagonist on Transient Lower Esophageal Sphincter Relaxations in Humans

Akinari Sawada; Atsushi Hashimoto; Risa Uemura; Hirokazu Yamagami; Tetsuya Tanigawa; Toshio Watanabe; Yasuhiro Fujiwara

doi:10.1159/000499333

Effect of EP1 Receptor Antagonist on Transient Lower Esophageal Sphincter Relaxations in Humans

Digestion ◽

10.1159/000499333 ◽

2019 ◽

Vol 101 (3) ◽

pp. 270-278

Author(s):

Akinari Sawada ◽

Atsushi Hashimoto ◽

Risa Uemura ◽

Hirokazu Yamagami ◽

Tetsuya Tanigawa ◽

...

Keyword(s):

Receptor Antagonist ◽

Lower Esophageal Sphincter ◽

Ep1 Receptor ◽

Esophageal Sphincter

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952 ONO-8539, a Novel Prostanoid EP1 Receptor Antagonist, Suppresses Transient Lower Esophageal Sphincter Relaxations in Monkeys

Gastroenterology ◽

10.1016/s0016-5085(14)60594-1 ◽

2014 ◽

Vol 146 (5) ◽

pp. S-167

Author(s):

Takashi Konemura ◽

Ichiro Date ◽

Hiroki Okada

Keyword(s):

Receptor Antagonist ◽

Lower Esophageal Sphincter ◽

Ep1 Receptor ◽

Esophageal Sphincter

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Effect of ONO-8539, a Prostanoid EP1 Receptor Antagonist, on Transient Lower Esophageal Sphincter Relaxation in Healthy Male Subjects

Gastroenterology ◽

10.1016/s0016-5085(17)30816-8 ◽

2017 ◽

Vol 152 (5) ◽

pp. S146

Author(s):

Akinari Sawada ◽

Risa Uemura ◽

Takashi Sugawa ◽

Koji Otani ◽

Koichi Taira ◽

...

Keyword(s):

Receptor Antagonist ◽

Lower Esophageal Sphincter ◽

Healthy Male ◽

Lower Esophageal Sphincter Relaxation ◽

Ep1 Receptor ◽

Esophageal Sphincter ◽

Male Subjects

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Effect of cholestyramine and cholecystokinin receptor antagonist CR1505 (loxiglumide) on lower esophageal sphincter pressure in man

Digestive Diseases and Sciences ◽

10.1007/bf01296114 ◽

1993 ◽

Vol 38 (10) ◽

pp. 1889-1892 ◽

Cited By ~ 6

Author(s):

A. A. M. Masclee ◽

J. B. M. J. Jansen ◽

L. C. Rovati ◽

C. B. H. W. Lamers

Keyword(s):

Receptor Antagonist ◽

Lower Esophageal Sphincter ◽

Lower Esophageal Sphincter Pressure ◽

Sphincter Pressure ◽

Cholecystokinin Receptor ◽

Esophageal Sphincter

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Effects of an N-methyl-D-aspartate (NMDA) receptor antagonist on transient lower esophageal sphincter relaxations (TLESRs) in the dog

Gastroenterology ◽

10.1016/s0016-5085(98)83214-9 ◽

1998 ◽

Vol 114 ◽

pp. A787 ◽

Cited By ~ 5

Author(s):

A. Lehmann

Keyword(s):

Nmda Receptor ◽

Receptor Antagonist ◽

Lower Esophageal Sphincter ◽

Nmda Receptor Antagonist ◽

Esophageal Sphincter

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Tension receptors in the proximal stomach: Are they relevant to triggering of transient lower esophageal sphincter relaxations (TLESRs)?

Gastroenterology ◽

10.1016/s0016-5085(01)82154-5 ◽

2001 ◽

Vol 120 (5) ◽

pp. A434-A434

Author(s):

S CAMAGNOLA ◽

P CANTU ◽

M ALLOCCA ◽

P BIANCHI ◽

R PENAGINI

Keyword(s):

Lower Esophageal Sphincter ◽

Proximal Stomach ◽

Esophageal Sphincter

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Diversity of K+ channels in circular smooth muscle of opossum lower esophageal sphincter

Gastroenterology ◽

10.1016/s0016-5085(01)80989-6 ◽

2001 ◽

Vol 120 (5) ◽

pp. A200-A200

Author(s):

Y ZHANG ◽

D MILLER ◽

W PATERSON

Keyword(s):

Smooth Muscle ◽

Lower Esophageal Sphincter ◽

K Channels ◽

Circular Smooth Muscle ◽

Esophageal Sphincter

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Axial Asymmetry in the lower esophageal sphincter: Comparison between patients with achalasia of the esophagus and normal subjects

Gastroenterology ◽

10.1016/s0016-5085(01)81209-9 ◽

2001 ◽

Vol 120 (5) ◽

pp. A244-A244

Author(s):

J LIU ◽

J PUCKETT ◽

N PEHLIVANOV ◽

R MITTAL

Keyword(s):

Lower Esophageal Sphincter ◽

Normal Subjects ◽

Esophageal Sphincter

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Inflammation-induced changes in arachidonic acid metabolism in cat lower esophageal sphincter (LES)

Gastroenterology ◽

10.1016/s0016-5085(01)81088-x ◽

2001 ◽

Vol 120 (5) ◽

pp. A219-A219

Author(s):

L CHENG ◽

W CAO ◽

K HARNETT ◽

J BEHAR ◽

P BIANCANI

Keyword(s):

Arachidonic Acid ◽

Lower Esophageal Sphincter ◽

Acid Metabolism ◽

Arachidonic Acid Metabolism ◽

Esophageal Sphincter ◽

Induced Changes

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Prostaglandin F2α(PGF2α)-induced contraction of human esophageal and lower esophageal sphincter circular smooth muscle

Gastroenterology ◽

10.1016/s0016-5085(01)81086-6 ◽

2001 ◽

Vol 120 (5) ◽

pp. A218-A218

Author(s):

W CAO ◽

K HARNETT ◽

J BEHAR ◽

P BIANCANI

Keyword(s):

Smooth Muscle ◽

Lower Esophageal Sphincter ◽

Prostaglandin F2α ◽

Circular Smooth Muscle ◽

Esophageal Sphincter

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High Resolution Manometry and pH stepup method on the localisation of the lower esophageal sphincter

Journal of Gastrointestinal and Liver Diseases ◽

10.15403/jgld.2014.1121.264.haa ◽

2017 ◽

Vol 26 (4) ◽

pp. 425-429

Author(s):

Atte Haarala ◽

Juli-Anna Linjamäki ◽

Heikki Tuominen ◽

Mika Kähönen

Keyword(s):

High Resolution ◽

Lower Esophageal Sphincter ◽

High Resolution Manometry ◽

Esophageal Sphincter

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