Long-Term Outcomes after Surgical Resection for Synchronous or Metachronous Hepatic and Pulmonary Colorectal Cancer Metastases

Digestion ◽  
2019 ◽  
Vol 101 (2) ◽  
pp. 144-155 ◽  
Author(s):  
Maurizio Zizzo ◽  
Carla Galeone ◽  
Luca Braglia ◽  
Lara Ugoletti ◽  
Alessandra Siciliani ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Surgical Resection ◽  
Long Term Outcomes ◽  
Cancer Metastases ◽  
Colorectal Cancer Metastases

ID: 3523886 LONG-TERM OUTCOMES AND SURVIVAL AFTER ENDOSCOPIC OR SURGICAL RESECTION FOR T1 COLORECTAL CANCER: A MULTICENTER RETROSPECTIVE STUDY

2021 ◽  
Vol 93 (6) ◽  
pp. AB86
Author(s):  
Hirohito Tanaka ◽  
Shiko Kuribayashi ◽  
Masanori Sekiguchi ◽  
Atsuo Iwamoto ◽  
Yoko Hachisu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Retrospective Study ◽  
Surgical Resection ◽  
Long Term Outcomes ◽  
T1 Colorectal Cancer

Long-Term Outcomes of Endoscopic Versus Surgical Resection of Superficial Submucosal Colorectal Cancer

2015 ◽  
Vol 60 (9) ◽  
pp. 2785-2792 ◽  
Author(s):  
Ji-Beom Kim ◽  
Ho Su Lee ◽  
Hyo Jeong Lee ◽  
Jihun Kim ◽  
Dong-Hoon Yang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Surgical Resection ◽  
Long Term Outcomes ◽  
Submucosal Colorectal Cancer

Long-Term Outcomes After Surgical Resection of Pulmonary Metastases From Colorectal Cancer

2015 ◽  
Vol 99 (2) ◽  
pp. 435-440 ◽  
Author(s):  
Hisashi Suzuki ◽  
Moriyuki Kiyoshima ◽  
Miyuki Kitahara ◽  
Yuji Asato ◽  
Ryuta Amemiya
Keyword(s):  
Colorectal Cancer ◽  
Surgical Resection ◽  
Pulmonary Metastases ◽  
Long Term Outcomes

scholarly journals Colorectal cancer metastases to the lungs: outcomes of surgical treatment and prognostic factors

2020 ◽  
Vol 10 (2) ◽  
pp. 33-41
Author(s):  
B. B. Akhmedov ◽  
P. V. Kononets ◽  
M. Yu. Fedyanin ◽  
Z. Z. Mamedli ◽  
S. S. Gordeev ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Overall Survival ◽  
Surgical Treatment ◽  
Survival Rate ◽  
Postoperative Complications ◽  
Progression Free Survival ◽  
Free Survival ◽  
Cancer Metastases ◽  
Colorectal Cancer Metastases

Objective: to evaluate short-term and long-term outcomes of surgical treatment for colorectal cancer metastases to the lungs and to analyze factors affecting the efficacy of surgery. Materials and methods. This study included 211 patients with colorectal cancer metastases to the lungs treated between 1994 and 2014. We enrolled patients with resectable or conventionally resectable metastases (according to chest computed tomography evaluated by a thoracic surgeon); the exclusion criteria were as follows: multiple primary tumors and age more than 85 years. We assessed the type of surgeries, frequency of R0 resections, incidence of postoperative complications, overall survival, and progression-free survival. Results. One hundred and sixty-two patients out of 211 (76.8 %) have undergone atypical lung resection. Forty-nine patients (23.2 %) have undergone pneumonectomy, bilobectomy, or lobectomy. The majority of patients (96.2 %) have had R0 resection, whereas 2.9 % of study participants have had R1 or R2 resections. One patient has undergone a trial surgery. Clinically significant postoperative complications were observed in 4 (2 %) patients; postoperative mortality was 0.5 % (1 case). The five-year overall survival rate was 52.7 %; the 5-year progression-free survival rate was 45.8 %. Development of metastases within 24 months after primary surgery was found to be a significant factor negatively affecting overall survival (hazard ratio 0.347; 95 % confidence interval 0.227–0.53; р <0.0001). Conclusions. Surgical treatment is currently the only truly effective treatment, which can improve long-term survival of patients with colorectal cancer metastases to the lungs; the best treatment results are achieved in patients with a relapse-free interval of more than 24 months. 

Long-term survival after hepatic and pulmonary resection of colorectal cancer metastases

2013 ◽  
Vol 108 (4) ◽  
pp. 220-224 ◽  
Author(s):  
Isabelle Sourrouille ◽  
Pierre Mordant ◽  
Léon Maggiori ◽  
Safi Dokmak ◽  
Guy Lesèche ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Pulmonary Resection ◽  
Term Survival ◽  
Long Term Survival ◽  
Cancer Metastases ◽  
Colorectal Cancer Metastases

New Trends in the Surgical Treatment of Colorectal Cancer Liver Metastases

1998 ◽  
Vol 84 (3) ◽  
pp. 281-288 ◽  
Author(s):  
Steven A. Curley ◽  
Rosario Vecchio
Keyword(s):  
Colorectal Cancer ◽  
Surgical Treatment ◽  
Liver Resection ◽  
Liver Metastases ◽  
Colorectal Cancer Liver Metastases ◽  
Term Survival ◽  
Long Term Survival ◽  
Cancer Metastases ◽  
Colorectal Cancer Metastases

Colorectal cancer is one of the most common solid tumors affecting people around the world. A significant proportion of patients with colorectal cancer will develop or will present with liver metastases. In some of these patients, the liver is the only site of metastatic disease. Thus, surgical treatment approaches are an appropriate and important treatment option in patients with liver-only colorectal cancer metastases. Resection of colorectal cancer liver metastases can produce long-term survival in selected patients, but the efficacy of liver resection as a solitary treatment is limited by two factors. First, a minority of patients with liver metastases have resectable disease. Second, the majority of patients who undergo successful liver resection for colorectal cancer metastases develop recurrent disease in the liver, extrahepatic sites, or both. In this paper, in addition to the results of liver resection for colorectal cancer metastases, we will review the results of cryoablation, heat ablation, and hepatic arterial chemotherapy using a surgically implanted pump. Each of these surgical treatment modalities can produce long-term survival in a subset of patients with liver-only colorectal cancer metastases, whereas systemic chemotherapy used alone rarely results in long-term survival in these patients. While surgical treatments provide the best chance for long-term survival or, in some cases, the best palliation in patients with colorectal cancer liver metastases, it is clear that further improvements in patient outcome will require multimodality therapy regimens.

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