The Effect of Morbidity and Sex on Postnatal Growth of Very Preterm Infants: A Multicenter Cohort Study

Neonatology ◽  
2019 ◽  
Vol 115 (4) ◽  
pp. 348-354 ◽  
Author(s):  
Carlos Zozaya ◽  
Alejandro Avila-Alvarez ◽  
Luis Arruza ◽  
Fermín García-Muñoz Rodrigo ◽  
Cristina Fernandez-Perez ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Infants ◽  
Postnatal Growth ◽  
Multicenter Cohort Study ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Multicenter Cohort

scholarly journals The Impact of Postnatal Systemic Steroids on the Growth of Preterm Infants: A Multicenter Cohort Study

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2729
Author(s):  
Carlos Zozaya ◽  
Alejandro Avila-Alvarez ◽  
Fermín García-Muñoz Rodrigo ◽  
María L. Couce ◽  
Luis Arruza ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Invasive Mechanical Ventilation ◽  
Postnatal Growth ◽  
Linear Regression Models ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort ◽  
Major Congenital Malformations ◽  
The Impact

Postnatal steroids, often used to prevent and treat bronchopulmonary dysplasia, may influence the growth of preterm infants, although data are scarce in the literature. This is a multicenter cohort study including surviving preterm infants <32 weeks at birth (n = 17,621) from the Spanish Neonatal Network SEN1500 database, without major congenital malformations. Linear regression models were adjusted for postnatal steroids, respiratory severity course (invasive mechanical ventilation at 28 days), progression to moderate–severe bronchopulmonary dysplasia (O2 at 36 weeks), length of stay, sex, gestational age and z-scores at birth. A subgroup analysis depending on the timing of administration, ventilation status at 28 days and moderate–severe BPD diagnosis was also performed. Overall, systemic postnatal steroids were not independently associated with poorer weight gain (0.1; 95% CI: −0.05 to 0.2 g/kg/day), linear growth (0; 95% CI: −0.03 to 0.01 cm/week) or head circumference growth (−0.01; 95% CI: −0.02 to 0 cm/week). Patients who received steroids after 28 days or who were not O2 dependent at 36 weeks after having received steroids gained more weight (0.22; 95% CI: 0.04 to 0.4 and 0.2; 95% CI: 0.004 to 0.5 g/kg/day, respectively). Globally, systemic postnatal steroids had no significant adjusted effect on postnatal growth.

Aortic growth arrest after preterm birth: a lasting structural change of the vascular tree

2011 ◽  
Vol 2 (4) ◽  
pp. 218-225 ◽  
Author(s):  
U. Schubert ◽  
M. Müller ◽  
A.-K. Edstedt Bonamy ◽  
H. Abdul-Khaliq ◽  
M. Norman
Keyword(s):  
Preterm Birth ◽  
Carotid Artery ◽  
Preterm Infants ◽  
Growth Failure ◽  
Later Life ◽  
Postnatal Growth ◽  
Direct Result ◽  
Arterial Tree ◽  
Very Preterm Infants ◽  
Very Preterm

Young people who are born very preterm exhibit a narrower arterial tree as compared with people born at term. We hypothesized that such arterial narrowing occurs as a direct result of premature birth. The aim of this study was to compare aortic and carotid artery growth in infants born preterm and at term. Observational and longitudinal cohort study of 50 infants (21 born very preterm, all appropriate for gestational age, 29 controls born at term) was conducted. Diameters of the upper abdominal aorta and common carotid artery were measured with ultrasonography at three months before term, at term and three months after term-equivalent age. At the first assessment, the aortic end-diastolic diameter (aEDD) was slightly larger in very preterm infants as compared with fetal dimensions. Fetal aortic EDD increased by 2.6 mm during the third trimester, whereas very preterm infants exhibited 0.9 mm increase in aEDD during the same developmental period (P < 0.001 for group difference). During the following 3-month period, aortic growth continued unchanged (+0.9 mm) in very preterm infants, whereas postnatal growth in term controls slowed down to +1.3 mm (P < 0.001 v. fetal aortic growth). At the final examination, aEDD was 22% and carotid artery EDD was 14% narrower in infants born preterm compared with controls, also after adjusting for current weight (P < 0.01). Aortic and carotid artery growth is impaired after very preterm birth, resulting in arterial narrowing. Arterial growth failure may be a generalized vascular phenomenon after preterm birth, with implications for cardiovascular morbidity in later life.

scholarly journals Cause of preterm birth and late-onset sepsis in very preterm infants: the EPIPAGE-2 cohort study

2021 ◽  
Author(s):  
Mathilde Letouzey ◽  
◽  
Laurence Foix-L’Hélias ◽  
Héloïse Torchin ◽  
Ayoub Mitha ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Birth ◽  
Preterm Infants ◽  
Late Onset ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Late Onset Sepsis

scholarly journals Neonatal Outcomes Following Extensive Delivery Room Resuscitation in Preterm Infants: A Multicenter Cohort Study

2012 ◽  
Vol 17 (suppl_A) ◽  
pp. 30A-30A
Author(s):  
AS Soraisham ◽  
N Singhal ◽  
K Aziz ◽  
A Lodha ◽  
SK Lee ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Infants ◽  
Neonatal Outcomes ◽  
Delivery Room ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort

Yes, we can - achieve adequate early postnatal growth in very preterm infants

2013 ◽  
Vol 102 (8) ◽  
pp. e345-e345
Author(s):  
C Maas ◽  
CF Poets ◽  
AR Franz
Keyword(s):  
Preterm Infants ◽  
Postnatal Growth ◽  
Very Preterm Infants ◽  
Very Preterm
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