Cleft Palate with or without Cleft Lip: The Role of Retronasal Triangle View and Maxillary Gap at 11–14 Weeks

2019 ◽  
Vol 46 (6) ◽  
pp. 353-359 ◽  
Author(s):  
Valentina De Robertis ◽  
Georgios Rembouskos ◽  
Tiziana Fanelli ◽  
Carmela Votino ◽  
Paolo Volpe
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Retronasal Triangle

No evidence for a role of CRISPLD2 in non-syndromic cleft lip with or without cleft palate in an Italian population

2011 ◽  
Vol 119 (1) ◽  
pp. 102-105 ◽  
Author(s):  
Ambra Girardi ◽  
Marcella Martinelli ◽  
Francesco Carinci ◽  
Paolo G. Morselli ◽  
Elisabetta Caramelli ◽  
...  
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Italian Population

Opioid Prescribing Practices in Cleft Lip and Cleft Palate Reconstruction

2021 ◽  
pp. 105566562199016
Author(s):  
Reuben A. Falola ◽  
Jordan T. Blough ◽  
Jasson T. Abraham ◽  
Sebastian M. Brooke
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Prescribing Patterns ◽  
Prescribing Practices ◽  
Opioid Prescribing ◽  
Cleft Lip Palate ◽  
Nonopioid Analgesics ◽  
Cleft Lip Repair ◽  
Palate Repair

Introduction: Currently, there is no consensus regarding the role of opioids in the management of perioperative pain in children undergoing cleft lip/palate repair. Method: The present study evaluated opioid prescribing patterns of surgeon members within the American Cleft Palate-Craniofacial Association surgeons utilizing an anonymous survey. Results: Respondents performing cleft lip repair typically operate on patients 3 to 6 months of age (86%), admit patients postoperatively (82%), and discharge them on the first postoperative day (72%). Comparatively, respondents performed palatoplasty between the ages of 10 and 12 months (62%), almost always admit the patients (99%), and typically discharge on the first postoperative day (78%). Narcotics were more frequently prescribed after palatoplasty than after cleft lip repair, both for inpatients (66%; 49%) and at discharge (38%; 22%). Oxycodone was the most prescribed narcotic (39.1%; 41.4%), typically for a duration of 1 to 3 days (81.5%; 81.2%). All surgeons who reported changing their narcotic regimen (34.4% dose, 32.8% duration) after cleft lip repair, decreased both parameters from earlier to later in their career. Similarly, surgeons who changed the dose (32.2%) and duration (42.5%) of narcotics after palatoplasty, mostly decreased both parameters (96%). Additionally, physicians with >15 years of practice were less likely to prescribe opioids in comparison with colleagues with ≤15 years of experience. Ninety-two percent of respondents endorsed prescribing nonopioid analgesics after prescribing cleft surgery, most commonly acetaminophen (85.7%; 85.4%). Conclusion: Cleft surgeons typically prescribe opioids to inpatients and rarely upon discharge. Changes to opioid-prescribing patterns typically involved a decreased dose and duration.

scholarly journals Assessment of role of consanguinity in formation of cleft lip and cleft palate

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1027-1031
Author(s):  
Joshini Shanmugam ◽  
Senthil Murugan P ◽  
Suresh V
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Chi Square ◽  
Consanguineous Marriages ◽  
Cleft Lip Palate ◽  
Chi Square Test ◽  
History Of ◽  
Autosomal Recessive Diseases

Consanguinity is considered a significant factor in autosomal recessive diseases; it has also been associated with congenital anomalies such as hydrocephalus, polydactilia and Cleft Lip and Palate deformities. The risk of congenital conditions is higher in subjects born of first degree consanguineous parents compared with those of non-consanguineous marriages. The aim of this study is to evaluate the prevalence of consanguinity with formation of cleft lip/ cleft palate formation in Tamil, Telugu population. This is a retrospective study. The details of 86,000 patient records were reviewed and analysed, out of which 76 patients who had undergone surgical treatment for cleft lip and cleft palate deformities between June 2019 to march 2020 were included in this study. The details like age, gender, family history and cleft diagnosis were evaluated and entered in SPSS and analysed through a chi-square test. It was observed that 11% of patients reported with history of consanguineous marriages which was associated with formation of cleft lip/palate. Within the limits of the study, it was concluded that consanguinity had a significant role in formation of cleft lip/cleft palate.

Cleft lip and cleft palate: Role of a pediatric dentist in its management

2017 ◽  
Vol 2 (1) ◽  
pp. 1 ◽  
Author(s):  
Rahul Kaul ◽  
Parul Jain ◽  
Subrata Saha ◽  
Subir Sarkar
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Pediatric Dentist

Oral Clefts and Vitamin Supplementation

2001 ◽  
Vol 38 (1) ◽  
pp. 76-83 ◽  
Author(s):  
L. C. M. Loffredo ◽  
J. M. P. Souza ◽  
J. A. S. Freitas ◽  
P. A. Mossey
Keyword(s):  
Folic Acid ◽  
Cleft Palate ◽  
Protective Effect ◽  
Cleft Lip ◽  
Statistical Significance ◽  
Brazilian Population ◽  
Environment Interaction ◽  
Multivitamin Supplementation ◽  
Periconceptional Period

Objectives The evidence linking low levels of folic acid and orofacial clefting (OFC) is presently equivocal. There is stronger evidence for the role of folic acid supplementation in protection against the occurrence and recurrence of neural tube defects. The present investigation tested the hypotheses that cleft lip, cleft palate, or both are inversely associated with maternal intake of dietary and supplemental vitamins during the periconceptional period and first 4 months of pregnancy in a Brazilian population. Design A population-based, case-control study of cleft lip with or without cleft palate (CL(P)) and isolated cleft palate (CP) in a Brazilian population. In structured interviews, case histories were taken from the mothers of a consecutive sample of 450 infants born with nonsyndromic OFC. Results Mothers who had children with CL(P) were less likely to have been supplemented during the periconceptional period. The statistical significance of the difference in prevalence of the use of supplements between mothers of patients and of controls was greater for the CL(P) group: p < .05 for CP and p < .001 for CL(P). Multivariate analysis confirmed this finding of a protective effect for both types of orofacial cleft. Conclusions The use of vitamin supplements in the first 4 months of pregnancy was suggestive of a protective effect against the occurrence of CP and CL(P) in this population. The significance of an association between multivitamin supplementation and OFC and the possible role of gene/environment interaction are discussed.

scholarly journals The Role of the Velopharyngeal Sphincter in the Speech of Patients with Cleft Palate or Cleft Lip and Palate Using Perceptual Methods

2016 ◽  
Vol 4 (4) ◽  
pp. 674-679 ◽  
Author(s):  
Tatjana Georgievska-Jancheska ◽  
Juliana Gjorgova ◽  
Mirjana Popovska
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Speech Disorders ◽  
Main Role ◽  
Probable Nature ◽  
Perceptual Assessment ◽  
Experimental Group ◽  
Insight Into

BACKGROUND: The velopharyngeal sphincter (VPS) plays the main role in speech formation. The cleft palate, due to the damage of the soft palate, leads to dysfunction of the velopharyngeal sphincter thus causing speech disorder.AIM: To establish a link between the nasal air escape and the perceptual symptoms in the speech of patients with cleft palate or cleft lip and palate using auditory-visual perceptual procedures for determining the influence the velopharyngeal dysfunction has on speech.MATERIAL AND METHODS: Twenty patients with speech disorders, out of which 10 have cleft palate or cleft lip and palate (experimental group), participated in the perceptual assessment by means of Czermak mirror fogging test for assessing the nasal air escape and Pittsburgh Weighted Speech Scale (PWSS) for assessing the probable nature of the velopharyngeal sphincter.RESULTS: The respondents with a considerable nasal air escape have a higher velopharyngeal inability, that is, probably incompetent nature of the velopharyngeal sphincter. There is a strong correlation between the nasal air escape and the probable nature of the velopharyngeal sphincter (the coefficient of linear correlation r = 0.9756). The calculated р-value is р = 0.000002.CONCLUSION: The perceptual speech symptoms and the nasal air escape provide unique insight into the state and role the velopharyngeal sphincter has in speech.

Role of the tongue in producing cleft palate in mice with spontaneous cleft lip

1963 ◽  
Vol 6 (1) ◽  
pp. 45-60 ◽  
Author(s):  
Daphne G. Trasler ◽  
F.C. Fraser
Keyword(s):  
Cleft Palate ◽  
Cleft Lip
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