Prognostic Significance of Metastatic Lymph Node Ratio in Patients with pN3 Gastric Cancer Who Underwent Curative Gastrectomy

2019 ◽  
Vol 42 (4) ◽  
pp. 209-216 ◽  
Author(s):  
Ahmet Bilici ◽  
Fatih Selcukbiricik ◽  
Mesut Seker ◽  
Basak B. Oven ◽  
Omer Fatih Olmez ◽  
...  
2009 ◽  
Vol 33 (11) ◽  
pp. 2378-2382 ◽  
Author(s):  
Naoto Fukuda ◽  
Yasuyuki Sugiyama ◽  
Akira Midorikawa ◽  
Hiroyuki Mushiake

2021 ◽  
Author(s):  
Zhipeng He ◽  
Dongchang Li ◽  
Siyu Liu ◽  
Endong Song ◽  
Yida Lu ◽  
...  

Abstract Background: The aim of this study was to examine the prognostic value of Metastatic lymph node ratio (MLNR) in patients with gastric cancer (GC) after curative gastrectomy and the potential for new indicators to strengthen the current guidelines.Methods:We retrospectively examined 3864 patients with GC who underwent curative gastrectomy between February 2011 and February 2016. Patients were classified into low-MLNR (L-MLNR), and high-MLNR (H-MLNR) groups according to adjusted X-tile cutoff-value of 0.25 for MLNR, and their clinicopathological characteristics and survival rates were compared.Results: Survival analysis indicated that MLNR was negatively associated with overall survival (OS) (P<0.001) and was an independent prognostic predictor in 3864 GC patients (P<0.001). Stratum analysis and univariate COX proportional hazards analysis were performed to validate the prognostic value of MLNR in various subgroups with clinicopathological characteristics (gender, age at surgery, tumor location, tumor size, type of gastrectomy, T stage, N stage, ELN, perineural invasion, vascular invasion, and TNM stage). MLNR is a prognostic indicator for patients with GC, regardless whether the number of lymph nodes examined is <16 or ≥16.Conclusions:The MLNR may become a new indicator for evaluating prognosis of patients with curative gastrectomy and complement the current guidelines.


2012 ◽  
Vol 36 (5) ◽  
pp. 1096-1101 ◽  
Author(s):  
Sung Ryol Lee ◽  
Hyung Ook Kim ◽  
Byung Ho Son ◽  
Jun Ho Shin ◽  
Chang Hak Yoo

2014 ◽  
Vol 25 ◽  
pp. iv227
Author(s):  
A. Taghizadeh Kermani ◽  
S.Z. Yahouyan ◽  
M. Ali Akbarian ◽  
M. Seilanian Tousi ◽  
P. Izadpanahi

2007 ◽  
Vol 14 (5) ◽  
pp. 1712-1717 ◽  
Author(s):  
Ho-Young Lee ◽  
Hong-Jo Choi ◽  
Ki-Jae Park ◽  
Jong-Sok Shin ◽  
Hyuk-Chan Kwon ◽  
...  

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