Correlation between Aortic Calcification Score and Biochemical Parameters in Hemodialysis Patients

2019 ◽  
pp. 40-51 ◽  
Author(s):  
Noriaki Maruyama ◽  
Terumi Higuchi ◽  
Michiko Ono ◽  
Hidetaka Oguma ◽  
Yoshihiro Nakamura ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Hemodialysis Patients ◽  
Aortic Calcification ◽  
Calcification Score

Aortic calcification index in hemodialysis patients with special reference to calcium metabolism.

1998 ◽  
Vol 31 (11) ◽  
pp. 1399-1404
Author(s):  
Jun-ichi Nagayoshi ◽  
Hajimu Yamada ◽  
Nobuo Oyama ◽  
Yoshio Maruyama ◽  
Katsunori Yoshida ◽  
...  
Keyword(s):  
Special Reference ◽  
Calcium Metabolism ◽  
Hemodialysis Patients ◽  
Aortic Calcification

scholarly journals Circulating microRNAs and vascular calcification in hemodialysis patients

2019 ◽  
Vol 47 (7) ◽  
pp. 2929-2939 ◽  
Author(s):  
Chien-Te Lee ◽  
Yueh-Ting Lee ◽  
You-Lin Tain ◽  
Hwee-Yeong Ng ◽  
Wei-Hung Kuo
Keyword(s):  
Vascular Calcification ◽  
Fibroblast Growth Factor 23 ◽  
High Sensitivity ◽  
Hemodialysis Patients ◽  
Blood Levels ◽  
Circulating Micrornas ◽  
Reactive Protein ◽  
Calcification Score ◽  
Circulating Levels

Objective Vascular calcification is common in chronic dialysis patients and is associated with increased morbidity and mortality. However, the role of circulating microRNAs (miRs) in vascular calcification has rarely been investigated. We aimed to determine circulating levels of miRs in hemodialysis patients, and analyzed their relationship with vascular calcification. Methods Sixty-one stable hemodialysis patients were enrolled, including 31 with vascular calcification and 30 without. Demographic and biochemical data were collected and reviewed. The presence and severity of vascular calcification were determined by lumber spine X-ray. Blood levels of miR29a/b, miR223, miR9, and miR21 were determined. Results Patients with vascular calcification were older (65.6 ± 9.0 vs. 59.1 ± 7.1 years) with a higher proportion of vascular disease (55% vs. 23%) than those without vascular calcification. Additionally, high-sensitivity C-reactive protein (3.90 vs 2.09 mg/dL) and fibroblast growth factor 23 (17311 vs. 6306 pg/mL) were significantly higher. Patients with vascular calcification also had higher levels of miR29a/b and miR223. Regression analysis indicated that age and miR29a were significant associates of the calcification score. Conclusions Hemodialysis patients with vascular calcification had higher levels of miR 29a/b and miR223 than those without vascular calcification, and circulating miR29a was associated with calcification severity.

Pelvic Artery Calcification Score Is a Marker of Vascular Calcification in Male Hemodialysis Patients

2018 ◽  
Vol 22 (5) ◽  
pp. 509-513 ◽  
Author(s):  
Tomohiko Matsuura ◽  
Takaya Abe ◽  
Mitsutaka Onoda ◽  
Daiki Ikarashi ◽  
Jun Sugimura ◽  
...  
Keyword(s):  
Vascular Calcification ◽  
Hemodialysis Patients ◽  
Calcification Score ◽  
Pelvic Artery

Cardiovascular Determinants of Mortality in Advanced Chronic Kidney Disease

2020 ◽  
Vol 51 (9) ◽  
pp. 726-735
Author(s):  
Roosa Lankinen ◽  
Markus Hakamäki ◽  
Kaj Metsärinne ◽  
Niina S. Koivuviita ◽  
Jussi P. Pärkkä ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Aortic Calcification ◽  
Abdominal Aortic Calcification ◽  
Advanced Chronic Kidney Disease ◽  
Abdominal Aortic ◽  
Calcification Score ◽  
Stage 4 ◽  
Ckd Stage ◽  
Artery Disease

Background: Patients with advanced chronic kidney disease (CKD stage 4-5) have an increased risk of death. To study the determinants of all-cause mortality, we recruited 210 consecutive CKD stage 4-5 patients not on dialysis to the prospective Chronic Arterial Disease, quality of life and mortality in chronic KIDney injury (CADKID) study. Methods: One hundred seventy-four patients underwent maximal bicycle ergometry stress testing and lateral lumbar radiography to study abdominal aortic calcification score and echocardiography. Carotid and femoral artery intima-media thickness and elasticity and brachial artery flow-mediated dilatation were measured in 156 patients. Results: The duration of follow-up was 42 ± 17 months (range 134–2,217 days). The mean age was 61 ± 14 years, and the estimated glomerular filtration rate was 12 (11–15) mL/min/1.73 m2. Thirty-six (21%) patients died during follow-up (time to death 835 ± 372 days). Seventy-five and 21 patients had diabetes and coronary artery disease, respectively, and all but one had hypertension. In the respective multivariate proportional hazards models adjusted for age, sex, and coronary artery disease, the significant determinants of mortality were troponin T, N-terminal pro-B-type natriuretic peptide, maximal ergometry performance, abdominal aortic calcification score, E/e′ ratio, and albumin. Conclusion: Stress ergometry performance, abdominal aortic calcification score, E/e′ of echocardiography, and plasma cardiac biomarkers and albumin predict mortality in advanced CKD.

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