Normality Ranges of Menstrual Fluid Volume During Reproductive Life Using Direct Quantification of Menses with Vaginal Cups

2019 ◽  
Vol 84 (4) ◽  
pp. 390-395 ◽  
Author(s):  
Manuel B. Donoso ◽  
Ramón Serra ◽  
Gregory E. Rice ◽  
María Teresa Gana ◽  
Carolina Rojas ◽  
...  
Keyword(s):  
Fluid Volume ◽  
Reproductive Life ◽  
Direct Quantification ◽  
Menstrual Fluid

scholarly journals Menstrual Fluid Factors Mediate Endometrial Repair

2021 ◽  
Vol 3 ◽  
Author(s):  
Lois A. Salamonsen
Keyword(s):  
Ex Vivo ◽  
Endometrial Thickness ◽  
Live Cells ◽  
Cellular Debris ◽  
Reproductive Life ◽  
Keratinocyte Cell ◽  
Culture Models ◽  
Cellular Components ◽  
Menstrual Fluid

Menstruation is a process whereby the outer functionalis layer of the endometrium is shed each month in response to falling progesterone and estrogen levels in a non-conception cycle. Simultaneously with the tissue breakdown, the surface is re-epithelialized, protecting the wound from infection. Once menstruation is complete and estrogen levels start to rise, regeneration progresses throughout the proliferative phase of the cycle, to fully restore endometrial thickness. Endometrial repair is unique compared to tissue repair elsewhere in the adult, in that it is rapid, scar-free and occurs around 400 times during each modern woman's reproductive life. The shedding tissue and that undergoing repair is bathed in menstrual fluid, which contains live cells, cellular debris, fragments of extracellular matrix, activated leukocytes and their products, soluble cellular components and extracellular vesicles. Proteomic and other analyses have revealed some detail of these components. Menstrual fluid, along with a number of individual proteins enhances epithelial cell migration to cover the wound. This is shown in endometrial epithelial and keratinocyte cell culture models, in an ex vivo decellularized skin model and in pig wounds in vivo. Thus, the microenvironment provided by menstrual fluid, is likely responsible for the unique rapid and scar-free repair of this remarkable tissue. Insight gained from analysis of this fluid is likely to be of value not only for treating endometrial bleeding problems but also in providing potential new therapies for poorly repairing wounds such as those seen in the aged and in diabetics.

scholarly journals Cyclical endometrial repair and regeneration

Development ◽  
2021 ◽  
Vol 148 (17) ◽  
Author(s):  
Lois A. Salamonsen ◽  
Jennifer C. Hutchison ◽  
Caroline E. Gargett
Keyword(s):  
Stem Cell ◽  
Progenitor Cells ◽  
Extracellular Vesicles ◽  
Stem Cell Niche ◽  
Wound Repair ◽  
Human Endometrium ◽  
Adult Tissues ◽  
Reproductive Life ◽  
Cell Niche ◽  
Menstrual Fluid

ABSTRACT Uniquely among adult tissues, the human endometrium undergoes cyclical shedding, scar-free repair and regeneration during a woman's reproductive life. Therefore, it presents an outstanding model for study of such processes. This Review examines what is known of endometrial repair and regeneration following menstruation and parturition, including comparisons with wound repair and the influence of menstrual fluid components. We also discuss the contribution of endometrial stem/progenitor cells to endometrial regeneration, including the importance of the stem cell niche and stem cell-derived extracellular vesicles. Finally, we comment on the value of endometrial epithelial organoids to extend our understanding of endometrial development and regeneration, as well as therapeutic applications.

Abstract #316: Reproductive Life Following Spinal Cord Injury: A Retrospective Study

2006 ◽  
Vol 12 ◽  
pp. 65
Author(s):  
Ghasak Mahmood ◽  
Sylvia J. Shaw ◽  
Yaga Szlachick ◽  
Rod Atkins ◽  
Stefan Bughi
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Retrospective Study ◽  
Cord Injury ◽  
Reproductive Life

The Effects of Direction and Velocity of Movement, and Intra-Articular Fluid Volume on Intra-Articular Pressue

1988 ◽  
Vol 01 (03/04) ◽  
pp. 113-121 ◽  
Author(s):  
S. F. Straface ◽  
P. J. Newbold ◽  
S. Nade
Keyword(s):  
Dynamic Pressure ◽  
Volume Of Fluid ◽  
Joint Capsule ◽  
Fluid Volume ◽  
Structural Configuration

levels. In joints with simulated acute effusion the effect of position on IAP was dependent upon the volume of fluid in the joint. The results indicate that dynamic pressure levels in the moving knee are related to the movements of the joint. The characteristic and reproducible patterns of pressure may reflect changes in the structural configuration of the joint capsule and surrounding tissues during movement, and are influenced by the amount of fluid in the joint.

Sonographic Assessment of Amniotic Fluid Volume using Single Deepest Pocket (SDP) among Igbo Women with Uncomplicated Singleton Pregnancies.

2019 ◽  
Vol 2 (1) ◽  
pp. 1-18
Author(s):  
Chijioke Okeudo ◽  
B.U. Ezem
Keyword(s):  
Amniotic Fluid ◽  
Gestational Age ◽  
Cross Sectional Study ◽  
Fluid Volume ◽  
Singleton Pregnancy ◽  
Cross Sectional ◽  
South Eastern ◽  
Amniotic Fluid Volume ◽  
The Mean ◽  
Singleton Pregnancies

Background: The amniotic fluid is fundamental for proper fetal development and growth. Ultrasound visualization of the amniotic fluid permits both subjective and objective estimates of the amniotic fluid. Objective: The objective of this study was to determine the reference values of normal single deepest pocket (SDP) – upper and lower limits, mean SDP and variation of the SDP with gestational age among Igbo women of South-Eastern Nigeria extraction carrying uncomplicated singleton pregnancy. Methodology: This was a prospective cross sectional study involving 400 women carrying uncomplicated singleton pregnancies and who were sure of the date of the first day of their last menstrual period. The single deepest pocket / maximum vertical pool were determined once at presentation at the hospital.. The study was conducted from January 1st to December 31st 2015. The second author carried out all the scanning. The SDP was obtained. Results: The womens’ mean and median ages were the same at 28 years. The gestational age range of the pregnancies was 14-41 weeks. The mean SDP was 5.8cm, while the 5th and 95th percentiles were 3.3cm and 8.5cm respectively. There was no difference in the mean SDP in both term and preterm. There was irregular but continuous rise of mean SDP to a peak of 6.8cm at gestational age of 39 weeks. In conclusion, the participants had a mean SDP of 5.8cm. There was also a positive correlation between SDP and Gestational age. We therefore recommend a longitudinal study to assess perinatal outcome and abnormal amniotic fluid volume among Igbo women of South-Eastern Nigeria. Key words: Single Deepest Pocket, Uncomplicated Singleton Pregnancy, Igbo Women.

Acute reduction of cerebrospinal fluid volume prior to spinal anesthesia: implications for sensory block extent

2020 ◽  
Vol 86 (6) ◽  
Author(s):  
Martin F. Bjurström ◽  
Niklas Mattsson ◽  
Andreas Harsten ◽  
Nicholas Dietz ◽  
Mikael Bodelsson
Keyword(s):  
Cerebrospinal Fluid ◽  
Spinal Anesthesia ◽  
Sensory Block ◽  
Fluid Volume ◽  
Cerebrospinal Fluid Volume
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