Anemia Management Considering the Pathophysiology of Elderly Chronic Kidney Disease Patients

2019 ◽  
pp. 135-143 ◽  
Author(s):  
Takahiro Kuragano ◽  
Kousuke Mizusaki ◽  
Tomoko Kimura ◽  
Takeshi Nakanishi
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Anemia Management ◽  
Elderly Chronic Kidney Disease

scholarly journals An Update on the Controversies in Anemia Management in Chronic Kidney Disease: Lessons Learned and Lost

Anemia ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Geoffrey Teehan ◽  
Robert L. Benz
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Randomized Trials ◽  
Lessons Learned ◽  
Patients With Diabetes ◽  
Anemia Management ◽  
Erythropoietin Deficiency ◽  
Stage Renal Disease ◽  
End Stage

Background. Erythropoietin deficiency and anemia occur in Chronic Kidney Disease (CKD) and may be treated with Erythropoietin Stimulating Agents (ESAs). The optimal hemoglobin, in non-End Stage Renal Disease CKD, is controversial.Methods. We review three recent randomized trials in anemia in CKD: CHOIR, CREATE, and TREAT.Results. CHOIR (N=1432) was terminated early with more frequent death and cardiovascular outcomes in the higher Hb group (HR 1.34: 95% C.I. 1.03–1.74,P=.03). CREATE (N=603) showed no difference in primary cardiovascular endpoints. Stroke was more common in the higher Hb group (HR 1.92; 95% C.I. 1.38–2.68;P<.001) in TREAT (N=4038).Conclusions. There is no benefit to an Hb outside the 10–12 g/dL range in this population. To avoid transfusions and improve Quality of Life, ESAs should be used cautiously, especially in patients with Diabetes, CKD, risk factors for stroke, and ESA resistance.

WITHDRAWAL OF ANGIOTENSIN ANTAGONISTS IN ELDERLY CHRONIC KIDNEY DISEASE PATIENTS

2018 ◽  
Vol 36 (Supplement 1) ◽  
pp. e289-e290
Author(s):  
V. Petkov Stoyanov ◽  
M.C. Jimenez Herrero ◽  
M.J. Gutierrez Sanchez ◽  
J.A. Martin Navarro
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Elderly Chronic Kidney Disease

scholarly journals Evaluation of Anemia Management by Algorithms in Patients with Chronic Kidney Disease Who Are Not Receiving Dialysis

2011 ◽  
Vol 64 (2) ◽  
Author(s):  
Marianna Leung ◽  
Jenelle Rogers ◽  
Monica Beaulieu ◽  
Adeera Levin ◽  
Shelley Burnett ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Anemia Management

scholarly journals Anemia management in chronic kidney disease

2010 ◽  
Vol 78 ◽  
pp. S3-S9 ◽  
Author(s):  
Steven Fishbane ◽  
Allen R. Nissenson
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Anemia Management
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