The Characteristics of Severe Chronic Upper-Airway Disease (SCUAD) in Patients with Allergic Rhinitis: A Real-Life Multicenter Cross-Sectional Italian Study

2019 ◽  
Vol 178 (4) ◽  
pp. 333-337 ◽  
Author(s):  
Federica Gani ◽  
Carlo Lombardi ◽  
Giacomo Bonizzoni ◽  
Giovanni Rolla ◽  
Luisa Brussino ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Real Life ◽  
Upper Airway ◽  
Airway Disease ◽  
Cross Sectional ◽  
Italian Study ◽  
Upper Airway Disease

Association between the use of electronic cigarettes and the prevalence of chronic rhinosinusitis and allergic rhinitis: a nationwide cross-sectional study

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
M.-S. Rha ◽  
H.-J. Cho ◽  
J.-H. Yoon ◽  
C.-H. Kim
Keyword(s):  
Allergic Rhinitis ◽  
Chronic Rhinosinusitis ◽  
Electronic Cigarettes ◽  
Adult Population ◽  
Upper Airway ◽  
Airway Disease ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
High Prevalence

Background: Whether the use of electronic cigarettes (ECs) is associated with upper airway diseases, including chronic rhinosinusitis (CRS) and allergic rhinitis (AR), remains unclear. Methods: We analyzed data from the nationwide cross-sectional surveys: the Korea National Health and Nutrition Examination Survey VI (2013–2015), VII (2016–2018), and VIII (2019). Logistic regression analysis was performed to assess the association between EC use and CRS or AR. Results: Among a total of 38,413 participants, 6.4% were former EC users and 2.5% were current EC users. Former EC users and current EC showed a significantly increased OR for CRS or AR compared with never EC users. In the subgroup analysis, the “current CC (conventional cigarette)-current EC” and the “current CC-formal EC” group had a significantly higher OR for CRS or AR than the “current CC-never EC” group. In addition, former CC smokers who currently use ECs showed a significantly higher OR for AR than former CC smokers without EC use. Conclusions: EC use is significantly associated with a high prevalence of CRS and AR in the adult population. These results indicate that the use of ECs may increase the risk of upper airway disease.

scholarly journals Upper airway symptoms associate with the eosinophilic phenotype of COPD

2021 ◽  
pp. 00184-2021
Author(s):  
Nicolai Obling ◽  
Vibeke Backer ◽  
John R Hurst ◽  
Uffe Bodtger
Keyword(s):  
Pulmonary Function Tests ◽  
Upper Airway ◽  
Airway Disease ◽  
Induced Sputum ◽  
Lower Airway ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Copd Patients ◽  
Airway Symptoms ◽  
Upper Airway Disease

BackgroundThere is growing evidence that upper airway symptoms coexist with lower airway symptoms in Chronic Obstructive Pulmonary Disease (COPD). Still, the prevalence and impact of upper airway disease on the nature and course of COPD remain unclear. We aimed to describe this in a cross-sectional study.MethodsWe examined a cohort of COPD patients with pulmonary function tests, induced sputum, blood eosinophils, atopy tests, CT of the paranasal sinuses. Lower airway symptoms were assessed using the COPD assessment test (CAT), and upper airway symptoms were assessed using the nasal subdomain of the 22-item Sino Nasal Outcome Test (SNOT22nasal). We recruited patients from five sites in Denmark and Sweden. We excluded patients with a history of asthma.FindingsIn total, 180 patients (female 55%, age 67 (±8) years, FEV1% 52.4 (±16.6), GOLD stage: A:18%, B:54%, C:3%, D:25%) were included in the study. Seventy-four patients (41%) reported high upper airway symptoms (high UAS defined as SNOT22nasal≥6) with a median score of 10 (IQR 8–13). Patients with high UAS reported higher CAT scores (17.4 (±7.5) versus 14.9 ±6.6, p<0.05) and displayed higher fractions of eosinophils in blood (median 3.0% (IQR 1.6–4.2%) versus 2.3% (IQR 1.4–3.1), p<0.05) and in induced sputum (median 1.8% (IQR 0.3–7.1%) versus median 0.5% (IQR 0–1.7%), p<0.05). No differences in atopy, CT findings or exacerbation rates were observed.ConclusionCOPD patients with upper airway disease showed increased evidence of eosinophilic disease and increased lower airway symptom burden.

scholarly journals The control of allergic rhinitis in real life: a multicenter cross-sectional Italian study

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Federica Gani ◽  
Carlo Lombardi ◽  
Laura Barrocu ◽  
Massimo Landi ◽  
Erminia Ridolo ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Real Life ◽  
Cross Sectional ◽  
Italian Study

Effects of air pollutants on upper airway disease

2016 ◽  
Vol 16 (1) ◽  
pp. 13-17 ◽  
Author(s):  
An-Soo Jang ◽  
Young Joon Jun ◽  
Moo Kyun Park
Keyword(s):  
Air Pollutants ◽  
Upper Airway ◽  
Airway Disease ◽  
Upper Airway Disease

Activin-A Is a Pro-Inflammatory Regulator in Type-2-Driven Upper Airway Disease

2018 ◽  
Vol 176 (1) ◽  
pp. 15-25 ◽  
Author(s):  
Adam M. Chaker ◽  
Ulrich Matthias Zissler ◽  
Nikolaos Poulos ◽  
Martin Wagenmann ◽  
Murat Bas ◽  
...  
Keyword(s):  
Upper Airway ◽  
Airway Disease ◽  
Activin A ◽  
Upper Airway Disease
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