Spinal Cord Stimulation for Restless Legs Syndrome: Case Series and Mechanistic Hypothesis

2019 ◽  
Vol 97 (1) ◽  
pp. 31-36
Author(s):  
Syed M. Adil ◽  
Jing L. Han ◽  
Beth A. Parente ◽  
Patrick Hickey ◽  
Shivanand P. Lad
Keyword(s):  
Spinal Cord ◽  
Restless Legs Syndrome ◽  
Spinal Cord Stimulation ◽  
Case Series ◽  
Restless Legs

Successful spinal cord stimulation for severe medication-refractory restless legs syndrome

2019 ◽  
Vol 34 (4) ◽  
pp. 585-586 ◽  
Author(s):  
Philippe De Vloo ◽  
Gaddum Duemani Reddy ◽  
Nathan Rowland ◽  
Francesco Sammartino ◽  
Maheleth Llinas ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Restless Legs Syndrome ◽  
Spinal Cord Stimulation ◽  
Restless Legs

Epidural Spinal Cord Stimulation: A Novel Therapy in the Treatment of Restless Legs Syndrome

2016 ◽  
Vol 92 ◽  
pp. 582.e15-582.e18 ◽  
Author(s):  
Marshall T. Holland ◽  
Leigh A. Rettenmaier ◽  
Oliver E. Flouty ◽  
Teri R. Thomsen ◽  
Nivedita U. Jerath ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Restless Legs Syndrome ◽  
Spinal Cord Stimulation ◽  
Novel Therapy ◽  
Restless Legs ◽  
Epidural Spinal Cord Stimulation

Spinal Cord Stimulation in Patients With Chronic Pain and Restless Legs Syndrome

2019 ◽  
Vol 13 (3) ◽  
pp. 110-113 ◽  
Author(s):  
David A. Byrne ◽  
Christopher M. Sobey ◽  
Jake Trahan ◽  
Kanika Bagai ◽  
Arthur Walters
Keyword(s):  
Spinal Cord ◽  
Chronic Pain ◽  
Restless Legs Syndrome ◽  
Spinal Cord Stimulation ◽  
Restless Legs

scholarly journals Successful application of burst spinal cord stimulation for refractory upper limb pain: a case series

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052110040
Author(s):  
Kuen Su Lee ◽  
Yoo Kyung Jang ◽  
Gene Hyun Park ◽  
In Jae Jun ◽  
Jae Chul Koh
Keyword(s):  
Spinal Cord ◽  
Upper Limb ◽  
Spinal Cord Stimulation ◽  
Therapeutic Potential ◽  
Case Series ◽  
Limb Amputation ◽  
Intractable Pain ◽  
Limb Pain ◽  
Cord Injury ◽  
Upper Limb Pain

Spinal cord stimulation (SCS) has been used to treat sustained pain that is intractable despite various types of treatment. However, conventional tonic waveform SCS has not shown promising outcomes for spinal cord injury (SCI) or postamputation pain. The pain signal mechanisms of burst waveforms are different to those of conventional tonic waveforms, but few reports have presented the therapeutic potential of burst waveforms for the abovementioned indications. This current case report describes two patients with refractory upper limb pain after SCI and upper limb amputation that were treated with burst waveform SCS. While the patients could not obtain sufficient therapeutic effect with conventional tonic waveforms, the burst waveforms provided better pain reduction with less discomfort. However, further studies are necessary to better clarify the mechanisms and efficacy of burst waveform SCS in patients with intractable pain.

Drug-Induced Restless Legs Syndrome

2018 ◽  
Vol 52 (7) ◽  
pp. 662-672 ◽  
Author(s):  
Edna Patatanian ◽  
Melanie K. Claborn
Keyword(s):  
Restless Legs Syndrome ◽  
English Language ◽  
Case Reports ◽  
Data Extraction ◽  
Case Series ◽  
Predisposing Factors ◽  
Drug Induced ◽  
Restless Legs ◽  
Drug Classes ◽  
Study Selection

Objective: To review the literature on drug-induced restless legs syndrome (DI-RLS). Data Sources: The review included a search for English-language literature from 1966 to December 2017 in the MEDLINE, PubMed, and Ovid databases using the following search terms: restless legs syndrome (RLS), periodic limb movement, adverse effects, and drug-induced. In addition, background articles on the pathophysiology, etiology, and epidemiology of RLS were retrieved. Bibliographies of relevant articles were reviewed for additional citations. Study Selection and Data Extraction: All case reports, case series, and review articles of DI-RLS were identified and analyzed. There were only a small number of controlled clinical trials, and most data were from case reports and case series. Results: Several drugs and drug classes have been implicated in DI-RLS, with antidepressants, antipsychotics, and antiepileptics having the most evidence. In addition, RLS may be linked with a number of disorders or underlying predisposing factors as well. Conclusions: The prevalence of RLS is variable and ranges from 3% to 19% in the general population. There are many predisposing factors to RLS, but an emerging body of evidence suggests that there is an association between numerous drugs and RLS.

scholarly journals Microstructure of the Midbrain and Cervical Spinal Cord in Idiopathic Restless Legs Syndrome: A Diffusion Tensor Imaging Study

SLEEP ◽  
2016 ◽  
Vol 39 (2) ◽  
pp. 423-428 ◽  
Author(s):  
Klaas Lindemann ◽  
Hans-Peter Müller ◽  
Albert C. Ludolph ◽  
Magdolna Hornyak ◽  
Jan Kassubek
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Restless Legs Syndrome ◽  
Diffusion Tensor ◽  
Cervical Spinal Cord ◽  
Imaging Study ◽  
Restless Legs ◽  
Diffusion Tensor Imaging Study

Improvement of restless legs syndrome by nabat: a case series and new hypotheses for research

2016 ◽  
Vol 13 (1) ◽  
Author(s):  
Ruohollah Seddigh ◽  
Amir-Abbas Keshavarz-Akhlaghi
Keyword(s):  
Restless Legs Syndrome ◽  
Case Series ◽  
Restless Legs ◽  
Underlying Mechanisms ◽  
Special Benefit

Abstract: Although many hypotheses have been suggested, the pathophysiology of restless legs syndrome (RLS) has not been fully understood. In this case series, we describe eleven cases with RLS whose symptoms subsided by the use of crystallized sucrose. This kind of sugar, known as: Case series.: All patients felt relief 30–60 min after taking 100 grams of dissolved: Sucrose seems to carry a special benefit for patients with RLS, and it provides evidence for growing literature demonstrating the different underlying mechanisms of RLS. Possible causes for this concurrence are also discussed.

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