High Prevalence of Pathological Hydrogen Breath Tests in Patients with Functional Dyspepsia

Digestion ◽  
2018 ◽  
pp. 1-6 ◽  
Author(s):  
Golo Petzold ◽  
Ahmad Amanzada ◽  
Thomas M. Gress ◽  
Volker Ellenrieder ◽  
Albrecht Neesse ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Breath Tests ◽  
High Prevalence ◽  
Hydrogen Breath Tests

Hydrogen Breath Tests

2017 ◽  
pp. 353-363
Author(s):  
Tamar Thurm ◽  
Yishai Ron
Keyword(s):  
Breath Tests ◽  
Hydrogen Breath Tests

Does the Addition of Methane Determinations Increase the Yield of Hydrogen Breath Tests for Sugar Malabsorption?

2004 ◽  
Vol 99 (4) ◽  
pp. 761-761 ◽  
Author(s):  
Daniel S Mishkin ◽  
Seymour Mishkin ◽  
David Blank ◽  
Morty Yalovsky
Keyword(s):  
Breath Tests ◽  
Hydrogen Breath Tests

scholarly journals Adding to the Burden: Gastrointestinal Symptoms and Syndromes in Multiple Sclerosis

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
David J. Levinthal ◽  
Ambreen Rahman ◽  
Salman Nusrat ◽  
Margie O’Leary ◽  
Rock Heyman ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Fecal Incontinence ◽  
Functional Dyspepsia ◽  
Gastrointestinal Symptoms ◽  
Functional Constipation ◽  
Full Extent ◽  
Gi Symptoms ◽  
High Prevalence ◽  
Dyspeptic Symptoms ◽  
Routine Assessment

Background. Multiple sclerosis (MS) patients often suffer from gastrointestinal (GI) symptoms. However, the full extent and prevalence of such symptoms are not clearly established. Thus, we sought to define the prevalence of GI symptoms and syndromes in those with MS.Methods. 218 MS patients completed self-reported demographic and clinical data questionnaires as well as several standardized surveys probing MS severity and GI health.Results. Nearly two thirds (65.6%) of patients endorsed at least one persistent GI symptom. Constipation (36.6%), dysphagia (21.1%), and fecal incontinence (15.1%) were common. Surprisingly, nearly 30% (28.4%) of the patients reported dyspeptic symptoms. Using validated diagnostic algorithms, patients met criteria for functional dysphagia (14.7%), functional dyspepsia (16.5%), functional constipation (31.7%), and IBS (19.3%), among others. Functional dysphagia, functional dyspepsia, and IBS were significantly more common in those with self-identified mood disorders.Conclusions. Constipation, fecal incontinence, and dysphagia are indeed frequent symptoms seen in MS patients. We also noted a ~30% prevalence of dyspepsia in this population. The mechanisms driving this association are not clear and require further study. However, due to this high prevalence, dyspeptic symptoms should be incorporated into the routine assessment of MS patients and, if found, may warrant collaborative referral with a GI specialist.

Food intolerance in patients with functional digestive disorders: an experience of administering hydrogen breath tests

2017 ◽  
Vol 7 (2) ◽  
pp. 16-22
Author(s):  
T.A. Stolyarova ◽  
◽  
A.S. Yurkevich ◽  
A.S. Portyanko ◽  
N.I. Saevich ◽  
...  
Keyword(s):  
Food Intolerance ◽  
Breath Tests ◽  
Digestive Disorders ◽  
Functional Digestive Disorders ◽  
Hydrogen Breath Tests

Carbohydrate Malabsorption: Quantification by Methane and Hydrogen Breath Tests

1994 ◽  
Vol 29 (9) ◽  
pp. 826-832 ◽  
Author(s):  
J. J. Rumessen ◽  
I. Nordgaard-Andersen ◽  
E. Gudmand-Høyer
Keyword(s):  
Breath Tests ◽  
Carbohydrate Malabsorption ◽  
Hydrogen Breath Tests

scholarly journals MODERN RESOURCES OF CELIAC DISEASE TREATMENT EFFECTIVENESS IMPROVEMENT

2020 ◽  
Vol 16 (3) ◽  
pp. 33-38
Author(s):  
O.Yu. Gubska ◽  
Yu.V. Chichula ◽  
A.K. Sizenko ◽  
L.M. Kupchik
Keyword(s):  
Small Intestine ◽  
Celiac Disease ◽  
Clinical Remission ◽  
Clinical Symptoms ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Breath Tests ◽  
Complete Clinical Remission ◽  
Comprehensive Examination ◽  
Hydrogen Breath Tests

Relevance. Although monotherapy with a gluten-free diet (BGD) for celiac disease is highly effective, it does not in all cases achieve complete remission of the disease. Therefore, an additional comprehensive examination of patients for the purpose of prescribing reasonable therapy is relevant. Objective: to study the causes of the persistence of clinical symptoms in patients with celiac disease who are on a gluten-free diet for 6 months. Materials and methods. Patients with celiac disease (n = 41) who were on a gluten-free diet (GFD) for 6 months were studied. The average age is 35.42 ± 0.45 years. Group 1 (n = 17) – patients who subjectively noted a positive dynamics of treatment and with a significant improvement in general condition, but without complete clinical remission. Group 2 (n = 24) – patients with unsatisfactory treatment results, no clinical effect from treatment, or weak positive dynamics on the background of GFD. The study included two stages: 1) assessment of patients' compliance and their diet (through the analysis of food diaries) in order to identify disorders of a gluten-free diet as the main cause of the persistence of clinical symptoms; 2) identification of other causes of the persistence of symptoms: exocrine pancreas insufficiency (EPI), lactase deficiency (LD) and the syndrome of increase bacterial growth (SIBR). A C13 triglyceride breath test (IRIS analyzer) was performed to diagnose EPI. To diagnose LD and SIBR in the small intestine, hydrogen breath tests (Micro H2-meter analyzer) were used – a test with lactose and D-xylose, respectively. Also, the titer of antibodies to tissue transglutaminase (TTG) to deaminated gliadin peptides (DPG) was determined in all patients, and their DPG/TTG ratio was calculated. Results. The main reason for the ineffectiveness of treatment is a violation of a gluten-free diet, found in 63.4% of subjects (incompletely formed mushy stool, polyfaeces, steatorrhea; recurrent abdominal pain, bloating, flatulence). Revision of food intake and elimination of sources of latent gluten from the diet of patients with celiac disease allowed to achieve complete serological remission (normalization of titers specific for celiac disease antibodies) in all patients, but complete clinical remission was achieved in only 34.6%. Therefore, it is concluded that there are other causes of incomplete remission of celiac disease associated with concomitant diseases of the digestive tract. Using carbon and hydrogen breath tests, it was found that, in addition to diet, the reasons for the lack of complete remission in patients with celiac disease are EPI (19%), SIBR in the small intestine (16%), LD (47%) and a combination of EPI with SIBR. Conclusion. The inclusion of respiratory tests (C13-triglyceride, hydrogen with lactose, and D-xylose) in a comprehensive examination of patients with celiac disease can significantly improve treatment outcomes and reduce the duration of clinical remission.

Sign in / Sign up

Export Citation Format

Share Document