Clinical Response to Subcutaneous Dermatophagoides pteronyssinus Immunotherapy in Children with Allergic Rhinitis and Asthma Is Independent of Sensitization to Blomia tropicalis Allergens

2018 ◽  
Vol 178 (2) ◽  
pp. 201-210 ◽  
Author(s):  
Shi Chen ◽  
Yiwu Zheng ◽  
Bing Chen ◽  
Haifeng Zhong ◽  
Feng Liao ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Response ◽  
Dermatophagoides Pteronyssinus ◽  
Blomia Tropicalis

The Importance of Nasal Provocation Testing in the Diagnosis of Dermatophagoides pteronyssinus-Induced Allergic Rhinitis

2021 ◽  
pp. 194589242110379
Author(s):  
Hao Xiao ◽  
Qiaoru Jia ◽  
Hongting Zhang ◽  
Li Zhang ◽  
Guo Liu ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Immunoglobulin E ◽  
Area Under The Curve ◽  
Roc Curves ◽  
Dermatophagoides Pteronyssinus ◽  
Allergen Specific Immunotherapy ◽  
Prick Test ◽  
Nasal Provocation ◽  
Provocation Testing ◽  
Nasal Provocation Testing

Background Allergen identification is the first step for allergen-specific immunotherapy (AIT) of allergic rhinitis (AR). Currently, the diagnosis of AR is based mainly on the positive results of the skin prick test (SPT) and/or serum specific immunoglobulin E (sIgE) measurement. However, the results of these two tests may not always directly correlate with AR. Objective To investigate the importance of nasal provocation testing (NPT) in the diagnosis of Dermatophagoides pteronyssinus (Der p)-induced AR. Methods Rhinitis patients willing to undergo AIT (n = 171) were enrolled. The correlations of Der p SPT, sIgE, NPT, and clinical symptom severity were assessed. Results NPT-positive responses were more common in patients with higher SPT and sIgE levels. The optimal cut-off value for a NPT-positive response for SPT was 5.5 mm and for sIgE was 2.77 kUA/L, based on the respective receiver operating characteristic (ROC) curves. The area under the curve (AUC) of the ROCs was 0.814 (SPT only) and 0.794 (sIgE only) and increased to 0.828 with the combination of SPT and sIgE. The Der p-NPT concentration was inversely correlated with SPT and sIgE levels ( r = −0.477, P < .001, and r = −0.461, P < .001, respectively), but none was correlated with the total nasal symptom score. Conclusion For patients who are willing to receive Der p AIT, NPT is a useful and safe test to confirm diagnosis prior to treatment initiation, especially in patients with lower levels of Der p SPT (< 5.5 mm) or sIgE (< 2.77 kUA/L).

Correlation between skin tests to Dermatophagoides pteronyssinus, Dermatophagoides siboney and Blomia tropicalis in Cuban asthmatics

2006 ◽  
Vol 34 (1) ◽  
pp. 23-26 ◽  
Author(s):  
R.L. Castro Almarales ◽  
M. Mateo Morejón ◽  
R.M. Naranjo Robalino ◽  
B.I. Navarro Viltre ◽  
M. Álvarez Castelló ◽  
...  
Keyword(s):  
Dermatophagoides Pteronyssinus ◽  
Skin Tests ◽  
Blomia Tropicalis

Skin Tests and Conjunctival and Bronchial Challenges with Extracts of Blomia tropicalis and Dermatophagoides pteronyssinus in Patients with Allergic Asthma and/or Rhinoconjunctivitis

2003 ◽  
Vol 131 (3) ◽  
pp. 182-188 ◽  
Author(s):  
J.C. García Robaina ◽  
I. Sánchez Machín ◽  
E. Fernández-Caldas ◽  
V. Iraola Calvo ◽  
C. Vázquez Moncholi ◽  
...  
Keyword(s):  
Allergic Asthma ◽  
Dermatophagoides Pteronyssinus ◽  
Skin Tests ◽  
Blomia Tropicalis

Evaluation of Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes (Acari: Pyroglyphidae) sensitivity in patients with allergic rhinitis: a comparative study

2018 ◽  
Vol 23 (2) ◽  
pp. 206
Author(s):  
Erhan ZEYTUN ◽  
Salih DOĞAN ◽  
Edhem Ünver ◽  
Fatih ÖZÇÜÇEK
Keyword(s):  
Allergic Rhinitis ◽  
Comparative Study ◽  
Clinical Assessment ◽  
Serum Levels ◽  
Specific Ige ◽  
Dermatophagoides Pteronyssinus ◽  
Total Ige ◽  
Serologic Tests ◽  
Stereo Microscope ◽  
Skin Prick Tests

This study was conducted to determine the sensitivity to Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes with skin prick tests (SPT) and serologic tests in patients with allergic rhinitis (AR), and to specifically search for those mites in homes of patients. A total of 51 participants, (23 patients and 28 controls) were utilized. Skin-prick tests with D. pteronyssinus and D. farinae allergens were performed on all participants, and serum levels of allergen-specific lgE and total IgE were also measured. Dust samples were collected from homes of all participants and examined under a stereo microscope. 977 D. pteronyssinus (mean 44.4/g) and 24 D. farinae (mean 4.0/g) were isolated from the homes of patients, whereas 35 D. pteronyssinus (mean 4.4/g), and four D. farinae (mean 2.0/g) were isolated from the homes of the controls. Patients with D. pteronyssinus in their homes had 95.5% sensitivity to the species according to SPT and 27.3 according to IgE. Patients with D. farinae in their homes had 83.3% sensitivity to the species according to SPT, and 50% according to IgE. Dermatophagoides pteronyssinus sensitivity in the controls was detected as 12.5% according to SPT; however, D. farinae sensitivity was not detected according to both SPT and mite-specific IgE. Differences between patients and controls utilizing SPT results was statistically significant, but not when using mite-specific IgE results. As a result, it was determined that patients with AR in Erzincan province were sensitized to D. pteronyssinus and D. farinae, and that their homes contained those species. It may be helpful to consider these findings in clinical assessment of patients with AR, and also in treatment utilizing immunotherapy techniques.

A contribution to the fauna of mites (Acari) in Fiji

2020 ◽  
Vol 25 (8) ◽  
pp. 1444-1460
Author(s):  
Qing-Hai Fan ◽  
Shivana Sweta Dayal ◽  
Hatch Michael Fong ◽  
Panapasa Rakuita ◽  
Jainesh Anish Ram
Keyword(s):  
Dermatophagoides Pteronyssinus ◽  
Blomia Tropicalis ◽  
First Time

We recently had the opportunity to collect some mite samples in Viti Levu and Vanua Levu of Fiji and found a couple of dozens of species. In this paper we present 32 species in three orders—Mesostigmata: 15 species in 11 genera in 9 families; Sarcoptiformes: 13 species in 13 genera in 10 families; Trombidiformes: 4 species in 4 genera in 3 families. The following 22 species are recorded for the first time from Fiji: Ameroseius womersleyi in Ameroseiidae, Lasioseius cuppa, L. latinoamericanus, L. pellitus  and L. penicilliger in Blattisociidae, Androlaelaps casalis in Laelapidae, Proctolaelaps aurora in Melicharidae, Propriosiopsis ovatus and Typhlodromus (Anthoseius) transvaalensis in Phytoseiidae; Funkotriplogynium ovulum in Triplogyniidae, Uroactinia hippocrepea in Uroactiniidae, Neotropacarus mumai and Schwiebea zingiberi in Acaridae, Glycycometus weelawadjiensis in Aeroglyphidae, Blomia tropicalis in Echimyopodidae, Pergalumna (P.) hawaiiensis hawaiiensis in Galumnidae, Nasozetes sumatrensis in Hemileiidae, Dermatophagoides pteronyssinus in Pyroglyphidae, Sudasia pontifica in Suidasiidae, Oulenziella bakeri in Winterschmidtiidae, Dactyloscirus smileyi in Cunaxidae, Tarsonemus rakowiensis in Tarsonemidae.

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