scholarly journals Individual and Combined Relationship between Reduced eGFR and/or Increased Urinary Albumin Excretion Rate with Mortality Risk among Insulin-Treated Patients with Type 2 Diabetes in Routine Practice

2018 ◽  
Vol 5 (2) ◽  
pp. 91-99
Author(s):  
Uchenna Anyanwagu ◽  
Richard Donnelly ◽  
Iskandar Idris
Keyword(s):  
Type 2 Diabetes ◽  
Mortality Risk ◽  
Urinary Albumin Excretion ◽  
Excretion Rate ◽  
Albumin Excretion Rate ◽  
Urinary Albumin ◽  
Routine Practice ◽  
Urinary Albumin Excretion Rate ◽  
Albumin Excretion

scholarly journals Choroidal thickness in relation to urinary albumin excretion rate in type 2 diabetes mellitus without retinopathy

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Doaa Maamoun Ashour ◽  
Amany Abd El-Fattah El-Shazly ◽  
Randa Hesham Ali Abdelgawad ◽  
Mohamed Ibrahim Saleh
Keyword(s):  
Type 2 Diabetes ◽  
Choroidal Thickness ◽  
Urinary Albumin Excretion ◽  
Excretion Rate ◽  
Albumin Excretion Rate ◽  
Urinary Albumin ◽  
Diabetic Patients ◽  
Urinary Albumin Excretion Rate ◽  
Albumin Excretion

Abstract Background To evaluate choroidal thickness (CT) in diabetic patients without diabetic retinopathy (DR) in relation to the urinary albumin excretion rate (UAER). Methods This is a prospective case-control study that included a consecutive sample of 120 patients with type 2 diabetes without clinically evident DR and a group of 60 matched healthy controls. Diabetic patients were included in two groups according to their UAER (normoalbuminuria and microalbuminuria). Complete ophthalmological examination was performed followed by optical coherence tomography (SD-OCT) for retinal and choroidal assessment. Twenty-four-hour urine samples were collected for UAER and blood samples for HbA1c and serum creatinine were obtained. Results The study included 180 eyes from 180 subjects in three groups. Patients with higher levels of albuminuria had a thinner choroid than normal controls, with decremental thinning as albuminuria progressed. Diabetics with normoalbuminuria showed no significant differences from controls. Choroidal thickness showed a significant moderate negative correlation with UAER (r  =  − 0.58, p  <  0.001). Multiple regression analyses for diabetic patients with microalbuminuria demonstrated that UAER is the most important determinant of subfoveal choroidal thickness (SFCT) (p  <  0.001). Conclusions Decreased CT was significantly correlated with UAER in diabetic patients without retinopathy and otherwise normal kidney functions. This decrease in thickness might be a predictor of DR.

scholarly journals Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients

2006 ◽  
Vol 50 (3) ◽  
pp. 466-471 ◽  
Author(s):  
Miriam Pecis ◽  
Lérida M.A. Zaslavsky ◽  
Fabrício B. Mallmann ◽  
Larissa Pante ◽  
Ana L.D. Krahe ◽  
...  
Keyword(s):  
Urinary Albumin Excretion ◽  
Excretion Rate ◽  
Visceral Obesity ◽  
Albumin Excretion Rate ◽  
Urinary Albumin ◽  
Diabetic Patients ◽  
Urinary Albumin Excretion Rate ◽  
Waist To Hip Ratio ◽  
Albumin Excretion

AIM: To analyze the relationship between visceral obesity and urinary albumin excretion rate (UAER). METHODS: A cross-sectional study of 73 normoalbuminuric (urinary albumin excretion rate < 20 µg/min) type 2 patients was performed. Patients were divided into two groups according to the median of UAER (7.5 µg/min). Office auscultatory blood pressure was measured in sitting position after a 10-min rest. RESULTS: Waist to hip ratio was higher in the group with UAER > 7.0 µg/min (0.98 ± 0.08), when compared to the other group (0.93 ± 0.08, p= 0.01). Waist to hip ratio significantly correlated with UAER (r= 0.28; p= 0.018). In multiple linear regression analysis, only waist to hip ratio was associated with UAER (r= 0.29; p= 0.04). A1c, DM duration and systolic BP levels were excluded from the model. CONCLUSIONS: Type 2 normoalbuminuric diabetic patients with higher levels of UAER could represent a group with an elevated risk for the development of cardiovascular diseases.

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