scholarly journals BrightOcular® Cosmetic Iris Implant: A Spectrum from Tolerability to Severe Morbidity

2018 ◽  
Vol 9 (2) ◽  
pp. 395-400 ◽  
Author(s):  
Mona K. Koaik ◽  
Ahmad M. Mansour ◽  
Alain Saad ◽  
Samir G. Farah
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Safety Profile ◽  
Corneal Edema ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Severe Morbidity ◽  
Ocular Side ◽  
First Case ◽  
Ocular Tolerability

Purpose: The BrightOcular® implants are the newest model of cosmetic iris devices that are currently advertised as safe. The previous generation known as NewColorIris® have had severe ocular side effects and were subsequently withdrawn from the market. There is little literature on the safety profile of BrightOcular® implants. Case Report: Herein we describe two cases with varying degrees of ocular tolerability. The first case had a normal ocular exam 1 year after implantation, whereas the second case had unilateral severe corneal edema requiring explantation of the iris device and Descemet membrane endothelial keratoplasty 9 months after bilateral implantation. Conclusions: These two cases attest to the unpredictability of the results of these cosmetic surgeries. Patients should be counseled about the vision-threatening complications of iris implants.

scholarly journals First Reported Case of Donor Related Candida Endophthalmitis after Descemet Membrane Endothelial Keratoplasty

2017 ◽  
Vol 11 (1) ◽  
pp. 117-121 ◽  
Author(s):  
Matthew Thompson ◽  
David Carli
Keyword(s):  
Case Report ◽  
Medical Treatment ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Retrospective Case ◽  
Descemet Membrane ◽  
Donor Material ◽  
First Case ◽  
Culture Positive ◽  
Candida Endophthalmitis

Purpose: To report the first case of Candida donor to host transmission following descemet membrane endothelial keratoplasty (DMEK) Methods: A retrospective case report. Results: A patient underwent uneventful DMEK. Following surgery the donor rim was culture positive for Candida. The patient developed fungal endophthalmitis that was treated medically with multiple injections of voriconazole and amphotericin. Medical treatment was unable to clear the infection and removal of the donor material was required. Following removal the infection subsided. Conclusion: Candida interface keratitis and endophthalmitis can occur following DMEK and may be difficult to treat medically. Early removal of the donor material should be considered.

Epithelial downgrowth after Descemet membrane endothelial keratoplasty

2020 ◽  
pp. 112067212091241
Author(s):  
Viet Nhat Hung Le ◽  
Florian Wabnig ◽  
Bjoern Bachmann ◽  
Claus Cursiefen
Keyword(s):  
Anterior Segment ◽  
Corneal Edema ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Visual Axis ◽  
Corneal Incision ◽  
Descemet Membrane ◽  
Clear Corneal Incision ◽  
Close Observation ◽  
Histopathologic Evaluation

Purpose: To describe a patient with epithelial downgrowth after Descemet membrane endothelial keratoplasty. Methods: Case report. Results: A 73-year-old woman underwent triple Descemet stripping automated endothelial keratoplasty for cataract and corneal edema secondary to Fuchs endothelial dystrophy in the left eye elsewhere. Three years later, Descemet membrane endothelial keratoplasty was performed at our department due to graft failure. One month after the operation, her vision improved to 20/32 and maintained stable. At the 14-month visit, her visual acuity decreased, and a routine examination revealed epithelial downgrowth at the posterior surface of the cornea and partly beneath the graft, accompanied by presumed graft rejection. Therefore, repeat Descemet membrane endothelial keratoplasty with epithelial scraping and intracameral injection of 5-fluorouracil was indicated. She recovered 20/25 vision by 1 month after the surgery. However, small sheet-like epithelial downgrowth recurred 1 month later. The epithelial downgrowth was limited to the peripheral margin of the Descemet membrane endothelial keratoplasty graft and did not affect the visual axis. Epithelial downgrowth showed “islands” with connection between epithelial downgrowth and clear corneal incision on anterior segment optical coherence tomography images. Histopathologic evaluation of the removed Descemet membrane endothelial keratoplasty graft confirmed conjunctival epithelium as the source. Under close observation at the current 4-year follow-up, the epithelial downgrowth remained stable and localized and her vision increased to 20/20. Conclusion: Epithelial downgrowth can occur after Descemet membrane endothelial keratoplasty. The limited progression of epithelial downgrowth in this patient suggests that this condition after Descemet membrane endothelial keratoplasty even in the recurrence stage may cause less damage than expected and may only need to be observed closely if no progression occurs.

Chlorpromazine: Case report and review of its ocular side-effects

1998 ◽  
Vol 10 (2) ◽  
pp. 73-79
Author(s):  
Elizabeth Grenier ◽  
Jennine Kirby
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Ocular Side

scholarly journals Severe ocular side effects of perhexilene maleate: case report.

1984 ◽  
Vol 68 (8) ◽  
pp. 553-560 ◽  
Author(s):  
J M Gibson ◽  
A R Fielder ◽  
A Garner ◽  
P Millac
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Ocular Side

Case Report of Quarter–Descemet Membrane Endothelial Keratoplasty for Fuchs Endothelial Dystrophy

Cornea ◽  
2017 ◽  
Vol 36 (1) ◽  
pp. 104-107 ◽  
Author(s):  
Thomas M. Müller ◽  
Itay Lavy ◽  
Lamis Baydoun ◽  
Jessica T. Lie ◽  
Isabel Dapena ◽  
...  
Keyword(s):  
Case Report ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane ◽  
Fuchs Endothelial Dystrophy

scholarly journals Adverse ocular effects of neuroleptic therapy: semiotics, pathogenesis and treatment

2022 ◽  
Vol 14 (4) ◽  
pp. 172-178
Author(s):  
A. A. Panov ◽  
A. A. Petukhova ◽  
Ya. V. Malygin ◽  
B. D. Tsygankov ◽  
M. A. Kazanfarova
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Clinical Manifestations ◽  
Corneal Edema ◽  
Acute Angle ◽  
Angle Closure ◽  
Antipsychotic Therapy ◽  
Ocular Side ◽  
Acute Angle Closure ◽  
Therapy Modification

Antipsychotics are widely used in psychiatric practice for treating schizophrenia, bipolar disorder, and other diseases, including those treated off-label. They manifest many adverse effects, including ophthalmic ones. Some of these effects, such as persistent mydriasis, cycloplegia, extraocular muscle dystonia, and visual hypersensitivity attacks are reversible, since they disappear after dose reduction or drug withdrawal. Yet other side effects, such as cataracts, corneal edema, acute angle closure glaucoma and retinopathy are threatening for sight and may lead to permanent visual acuity decline and even blindness. The review provides data on the incidence of ocular side effects (both typical and atypical) of multiple antipsychotics, their clinical manifestations, pathogenesis and treatment. Eye examination is recommended for patients taking antipsychotics in the early periods of treatment and then twice a year. The psychiatrists need to know about the adverse effects of individual drugs whilst the ophthalmologists should be aware of their semiotics, pathogenesis and treatment, since timely diagnosis and treatment of pathological changes, together with antipsychotic therapy modification, prevent the development of severe and irreversible visual impairment in the majority of cases.

scholarly journals Collagen Corneal Cross-linking in a Keratoconic Eye with Diffuse Corneal Edema

2012 ◽  
Vol 1 (2) ◽  
pp. 134-139
Author(s):  
Hanna Garzozi ◽  
Yossef Pickel ◽  
Ankur Barua
Keyword(s):  
Case Report ◽  
Penetrating Keratoplasty ◽  
Corneal Edema ◽  
Cross Linking ◽  
Endothelial Keratoplasty ◽  
Review Of Literature ◽  
Safety And Efficacy ◽  
Definitive Solution

ABSTRACT Corneal cross-linking has proven safety and efficacy in arresting the progression of keratoconus. Its use has been extended to resolution of corneal edema. We present a case report and review of literature on the treatment of corneal edema using corneal cross-linking. Corneal cross-linking seems to be an effective method in reducing corneal edema at least as a temporary measure till definitive solution, such as penetrating keratoplasty (PKP) or Descemet's stripping automated endothelial keratoplasty (DASEK) is preformed. How to cite this article Barbara R, Garzozi H, Barbara A, Pickel Y, Barua A. Collagen Corneal Cross-linking in a Keratoconic Eye with Diffuse Corneal Edema. Int J Kerat Ect Cor Dis 2012;1(2):134-139.

Descemet Membrane Endothelial Keratoplasty for Corneal Edema and Visually Significant Descemet Membrane Scrolls Due to Syphilitic Keratitis

Cornea ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Daliya Dzhaber ◽  
Amar P. Shah ◽  
Sander Dubovy ◽  
Umangi Patel ◽  
Ellen H. Koo
Keyword(s):  
Corneal Edema ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane
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