Innate Myeloid Cell Subset-Specific Gene Expression Patterns in the Human Colon are Altered in Crohn’s Disease Patients

Digestion ◽  
2018 ◽  
Vol 99 (3) ◽  
pp. 194-204 ◽  
Author(s):  
Yuki Sekido ◽  
Yoshiaki Yasumizu ◽  
Junichi Nishimura ◽  
Hisako Kayama ◽  
Hiroshi Matsuno ◽  
...  
Keyword(s):  
Gene Expression ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Expression Patterns ◽  
Cell Subset ◽  
Myeloid Cell ◽  
Human Colon ◽  
Gene Expression Patterns ◽  
Specific Gene ◽  
Specific Gene Expression

scholarly journals Regional and cell-specific gene expression patterns during petal development.

1992 ◽  
Vol 4 (11) ◽  
pp. 1383-1404 ◽  
Author(s):  
G N Drews ◽  
T P Beals ◽  
A Q Bui ◽  
R B Goldberg
Keyword(s):  
Gene Expression ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Petal Development

scholarly journals Microgenomic analysis reveals cell type-specific gene expression patterns between ray and fusiform initials within the cambial meristem ofPopulus

2008 ◽  
Vol 180 (1) ◽  
pp. 45-56 ◽  
Author(s):  
Nadia Goué ◽  
Marie-Claude Lesage-Descauses ◽  
Ewa J. Mellerowicz ◽  
Elisabeth Magel ◽  
Philippe Label ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Specific Gene ◽  
Cell Type ◽  
Specific Gene Expression ◽  
Fusiform Initials ◽  
Cell Type Specific

scholarly journals Plant-parasitic nematodes respond to root exudate signals with host-specific gene expression patterns

2019 ◽  
Vol 15 (2) ◽  
pp. e1007503 ◽  
Author(s):  
Christopher A. Bell ◽  
Catherine J. Lilley ◽  
James McCarthy ◽  
Howard J. Atkinson ◽  
P. E. Urwin
Keyword(s):  
Gene Expression ◽  
Root Exudate ◽  
Expression Patterns ◽  
Parasitic Nematodes ◽  
Gene Expression Patterns ◽  
Specific Gene ◽  
Plant Parasitic Nematodes ◽  
Specific Gene Expression ◽  
Plant Parasitic

scholarly journals Analysis of region specific gene expression patterns in the heart and systemic responses after experimental myocardial ischemia

Oncotarget ◽  
2017 ◽  
Vol 8 (37) ◽  
pp. 60809-60825
Author(s):  
Matthias Zimmermann ◽  
Lucian Beer ◽  
Robert Ullrich ◽  
Dominika Lukovic ◽  
Elisabeth Simader ◽  
...  
Keyword(s):  
Gene Expression ◽  
Myocardial Ischemia ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Experimental Myocardial Ischemia ◽  
Systemic Responses

Regional and Cell-Specific Gene Expression Patterns during Petal Development

1992 ◽  
Vol 4 (11) ◽  
pp. 1383 ◽  
Author(s):  
Gary N. Drews ◽  
Thomas P. Beals ◽  
Anhthu Q. Bui ◽  
Robert B. Goldberg
Keyword(s):  
Gene Expression ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Petal Development

Clinical phenotype and gene expression profile in Crohn's disease

2007 ◽  
Vol 292 (1) ◽  
pp. G298-G304 ◽  
Author(s):  
Claudio Csillag ◽  
Ole Haagen Nielsen ◽  
Rehannah Borup ◽  
Finn Cilius Nielsen ◽  
Jørgen Olsen
Keyword(s):  
Gene Expression ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Intracellular Transport ◽  
Clinical Phenotype ◽  
Expression Profiles ◽  
Expression Patterns ◽  
Principal Component ◽  
Gene Profiling ◽  
Gene Expression Patterns

The clinical course varies significantly among patients with Crohn's disease (CD). This study investigated whether gene expression profiles generated by DNA microarray technology might predict disease progression. Biopsies from the descending colon were obtained colonoscopically from 40 CD patients. Gene profiling analyses were performed using a Human Genome U133 Plus 2.0 GeneChip Array, and summarization into a single expression measure for each probe set was performed using the robust multiple array procedure. Principal component analysis demonstrated that three components explain two-thirds of the total variation. The most important parameters for the determination of the colonic gene expression patterns were the presence of disease (CD) and presence of inflammation. Superimposition of clinical phenotype data revealed a grouping of the samples from patients with stenosis toward negative values on the axis of the second principal component. The functional annotation analysis suggested that the expression of genes involved in intracellular transport and cytoskeletal organization might influence the development of stenosis. In conclusion, even though most variation in the colonic gene expression patterns is due to presence or absence of CD and inflammation status, the development of stenosis is a parameter that affects colonic gene expression to some extent.

Sign in / Sign up

Export Citation Format

Share Document