Rituximab as a Therapeutic Option for Steroid-Sensitive Minimal Change Nephrotic Syndrome in Adults

Author(s):  
Yuko Iwabuchi ◽  
Takahito Moriyama ◽  
Mitsuyo Itabashi ◽  
Takashi Takei ◽  
Kosaku Nitta
Author(s):  
M. A. Lewis ◽  
E. M. Baildom ◽  
N. Davies ◽  
I. B. Houston ◽  
R. J. Postlethwaite

1984 ◽  
Vol 18 ◽  
pp. 372A-372A
Author(s):  
Kishore Phadke ◽  
Orlando Adamson ◽  
Anthony Nicastri ◽  
Howard Trachtman ◽  
Amir Tejani

2018 ◽  
Vol 8 (2) ◽  
pp. 178-181
Author(s):  
Hideaki Yamabe ◽  
Mitsuaki Kaizuka ◽  
Satoru Tsunoda ◽  
Michiko Shimada

Minimal change nephrotic syndrome (MCNS) is the most common cause of nephrotic syndrome in children and can also present in adults. Corticosteroids generally induce remission of MCNS, and relapses are common after reduction or discontinuation of corticosteroids. We experienced a rare case of steroid-sensitive MCNS where the patient relapsed after 52 years of remission. The patient was a 61-year-old Japanese male who visited our clinic for an edema of the lower extremities which had already persisted for a few days. Laboratory testing showed massive urinary protein and low serum total protein and albumin levels. Therefore, he was diagnosed with nephrotic syndrome. He had a history of nephrotic syndrome that initially developed when he was 5 years old. Although corticosteroids reduced the urinary protein level, frequent relapses occurred when their doses were reduced, or when they were discontinued. He had previously experienced a relapse when he was 9 years old. For his current condition, treatment with corticosteroids and diuretics for 1 week reduced his edema and proteinuria. We suspected that this is a case of MCNS and that the present event is a relapse. Thus, we concluded that this is a very rare case of steroid-sensitive nephrotic syndrome that relapsed after 52 years of remission.


2011 ◽  
Vol 45 (2) ◽  
pp. 179-185
Author(s):  
Hideyo Oguchi ◽  
Marohito Murakami ◽  
Takashi Araki ◽  
Mariko Meguro ◽  
Akinori Hashiguchi ◽  
...  

2012 ◽  
Vol 28 (5) ◽  
pp. 1225-1232 ◽  
Author(s):  
T. Takei ◽  
M. Itabashi ◽  
T. Moriyama ◽  
C. Kojima ◽  
S. Shiohira ◽  
...  

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