Diabetic Retinopathy and Heart Disease

2019 ◽  
pp. 54-63
Author(s):  
Debra Quek Qiao Yun ◽  
Ning (Danny) Cheung
Keyword(s):  
Diabetic Retinopathy ◽  
Heart Disease

scholarly journals Diabetic Retinopathy and the Risk of Coronary Heart Disease: The Atherosclerosis Risk in Communities Study

Diabetes Care ◽  
2007 ◽  
Vol 30 (7) ◽  
pp. 1742-1746 ◽  
Author(s):  
N. Cheung ◽  
J. J. Wang ◽  
R. Klein ◽  
D. J. Couper ◽  
A. R. Sharrett ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Diabetic Retinopathy ◽  
Heart Disease ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk

Coronary heart disease and diabetic retinopathy in newly diagnosed diabetes in Da Qing, China: The Da Qing IGT and Diabetes Study

1991 ◽  
Vol 28 (2) ◽  
pp. 169-173 ◽  
Author(s):  
Ying-Hua Hu ◽  
Xiao-Ren Pan ◽  
Ping-An Liu ◽  
Gung-Wei Li ◽  
Barbara V. Howard ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Diabetic Retinopathy ◽  
Heart Disease ◽  
Newly Diagnosed ◽  
Diagnosed Diabetes ◽  
Newly Diagnosed Diabetes

Abstract 3241: Long-TermSurvival after Coronary Artery Bypass versus Percutaneous Coronary Intervention with Bare Metal Stent Implantation in Patients with Diabetic Retinopathy

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Takayuki Ohno ◽  
Yoshihiro Suematsu ◽  
Noboru Motomura ◽  
Minoru Ono ◽  
Hideo Fujita ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Overall Survival ◽  
Percutaneous Coronary Intervention ◽  
Diabetic Retinopathy ◽  
Heart Disease ◽  
Artery Bypass ◽  
Coronary Intervention ◽  
Bare Metal ◽  
Percutaneous Coronary

Background : Coronary heart disease is the leading cause of death in diabetic population. Compared with diabetics without retinopathy, diabetics with retinopathy have an increased risk of myocardial infarction and death from coronary heart disease. Therefore, it is crucial to select an appropriate revascularization method in this considerable high-risk group. Methods: Between 1996 and 2004, a total of 149 patients with diabetic retinopathy underwent revascularization, either coronary artery bypass surgery (CABG) (n=56) or percutaneous coronary intervention with bare metal stents (BMS) (n=94). We compared overall survival rates of the two methods. Mortality was estimated according to Kaplan-Meier methods and was compared using the log-rank test. Results: The average follow-up from the time of the initial revascularization was 59.7 ± 33.3 months. During the entire follow-up, there was 8(14.5%)death in the CABG group and 27(28.7%) deaths in the BMS group. The average duration between death and revascularization was 81.3 ± 24.6 for the CABG group and 29.9 ± 23.8 for the BMS group (P<0.001). The 6-year overall survival was 94.8% for the CABG group and 73.6% for the BMS group. Mortality curves differed significantly between the two groups (P=0.004) (Figure ). After adjustment for baseline characteristics including age, sex, HbA1c, insulin, serum creatinine, ejection fraction, and the extent of coronary disease, the hazard ratio of death afforded by CABG was 0.36 (95% confidence interval, 0.15–0.87; P=0.023). Conclusions: In patients with diabetic retinopathy, CABG conferred survival benefit over BMS implantation.

scholarly journals Survival Time of Visual Gains after Diabetic Vitrectomy and Its Relationship with Ischemic Heart Disease

2020 ◽  
Vol 17 (1) ◽  
pp. 310
Author(s):  
Abdah Khairiah Che Md Noor ◽  
Evelyn Li Min Tai ◽  
Yee Cheng Kueh ◽  
Ab Hamid Siti-Azrin ◽  
Zamri Noordin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Visual Acuity ◽  
Diabetic Retinopathy ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Survival Time ◽  
Proliferative Diabetic Retinopathy ◽  
Vision Loss ◽  
Ischemic Heart ◽  
Vitrectomy Surgery

Vitrectomy surgery in proliferative diabetic retinopathy improves the vision-related quality of life. However, there is lack of data on the duration of maintenance of visual gains post vitrectomy. This study thus aimed to determine the survival time of visual gains and the prognostic factors of vision loss after vitrectomy surgery for complications of proliferative diabetic retinopathy. A retrospective cohort study was conducted in an ophthalmology clinic in Malaysia. We included 134 patients with type 2 diabetes mellitus on follow-up after vitrectomy for proliferative diabetic retinopathy. Visual acuity was measured using the log of minimum angle of resolution (LogMar). A gain of ≥0.3 LogMar sustained on two subsequent visits was considered evidence of visual improvement post vitrectomy. Subjects were considered to have vision loss when their post-operative visual acuity subsequently dropped by ≥0.3 LogMar. Kaplan–Meier analysis was used to determine the survival time of visual gains. Cox Proportional Hazard regression was used to determine the prognostic factors of vision loss. The median age of patients was 56.00 years (IQR ± 10.00). The median duration of diabetes mellitus was 14.00 years (IQR ± 10.00). Approximately 50% of patients with initial improvement post vitrectomy subsequently experienced vision loss. The survival time, i.e., the median time from surgery until the number of patients with vision loss formed half of the original cohort, was 14.63 months (95% CI: 9.95, 19.32). Ischemic heart disease was a significant prognostic factor of vision loss. Patients with underlying ischemic heart disease (adjusted HR: 1.97, 95% CI: 1.18, 3.33) had a higher risk of vision loss post vitrectomy, after adjusting for other factors. Approximately half the patients with initial visual gains post vitrectomy maintained their vision for at least one year. Ischemic heart disease was a poor prognostic factor for preservation of visual gains post vitrectomy.

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