scholarly journals Convulsive Seizures as Presenting Symptom of Metronidazole-Induced Encephalopathy: A Case Report

2018 ◽  
Vol 10 (1) ◽  
pp. 34-37 ◽  
Author(s):  
Caspar Godthaab Sørensen ◽  
William Kristian Karlsson ◽  
Faisal Mohammad Amin ◽  
Mette Lindelof
Keyword(s):  
Case Report ◽  
Rare Condition ◽  
Pleural Empyema ◽  
Clinical Suspicion ◽  
Cerebellar Dysfunction ◽  
Blood Samples ◽  
Hyperintense Signal ◽  
Signal Changes ◽  
Convulsive Seizures

Introduction: Encephalopathy and convulsive seizures are rare manifestations of metronidazole toxicity. The incidence is unknown, but the condition has most frequently been reported in patients in their fifth to sixth decades. Usually, this condition is regarded as reversible, but permanent deficits and even death have been reported. Case Report: A 66-year-old female patient undergoing metronidazole treatment for pleural empyema was admitted to our institution after her second episode of seizure. Over the course of 1 week after admittance, the patient developed several convulsive seizures along with progressive cerebellar dysfunction and cognitive impairment. MRI revealed bilateral, symmetrical hyperintense signal changes in the pons and dentate nuclei. EEG, ECG, lumbar puncture, and blood samples were normal. The patient improved already 2–3 days after discontinuation of metronidazole and was discharged fully recovered after 17 days. Follow-up clinical assessment and MRI were unremarkable. Conclusion: Metronidazole-induced encephalopathy is a rare condition, and due to a general lack of awareness the diagnosis is often delayed. This condition should be considered in metronidazole-treated patients presenting with unprovoked seizures, myoclonus, cerebellar signs, and encephalopathy. Characteristic MRI lesions may support the clinical suspicion.

scholarly journals Inflammatory Pseudotumor of the Liver Complicated by Lung Necrosis and Pleural Empyema: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
Klaus Steinbrück ◽  
Marcelo Enne ◽  
Reinaldo Fernandes ◽  
Jose M. Martinho ◽  
Lúcio F. Pacheco-Moreira
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Inflammatory Pseudotumor ◽  
Liver Tumors ◽  
Rare Condition ◽  
Pleural Empyema ◽  
Important Differential Diagnosis ◽  
Uncommon Complication

Inflammatory pseudotumor of the liver (IPTL) is a rare condition, but an important differential diagnosis of hepatic space-occupying lesions. It may regress spontaneously and mimic other liver tumors. Complications are usually intrahepatic. Herein, we present a case of IPTL which developed pleural empyema and lung necrosis as an uncommon complication.

Reimplantation of an Inverted Maxillary Premolar: Case Report of a Multidiscplinary Treatment Approach

2009 ◽  
Vol 33 (4) ◽  
pp. 279-282 ◽  
Author(s):  
Ayca Ulusoy ◽  
Murat Akkocaoglu ◽  
Seden Akan ◽  
Ilken Kocadereli ◽  
Zafer Cehreli
Keyword(s):  
Case Report ◽  
Root Resorption ◽  
Treatment Approach ◽  
Multidisciplinary Treatment ◽  
Rare Condition ◽  
Treatment Alternative ◽  
Normal Position ◽  
Sufficient Space ◽  
Viable Treatment

Inversion of premolars is an extremely rare condition, which usually requires extraction. This case report describes the inversion of an impacted maxillary second premolar in an 11-year-old male, and the multidisciplinary treatment approach for bringing the tooth into a normal position within the arch. In order to provide sufficient space for surgical reimplantation of the tooth, the mesially-drifted neighbouring maxillary first molar was first endodontically treated, followed by orthodontic distalization of the tooth. The inverted tooth was removed surgically and reimplanted without the use of splints for stabilization. After a 12-month follow-up period, the tooth maintained its vitality without any root resorption. Reimplantation of impacted inverted premolars can be a viable treatment alternative to extraction

scholarly journals Haemorrhagic suprarenal pseudocysts: a systematic review of a rare condition from family physicians’ perspective during the COVID-19 global pandemic

2021 ◽  
Vol 3 (1) ◽  
pp. 22-25
Author(s):  
Adekunle Olowu ◽  
Adel Abbas Alzehairy
Keyword(s):  
Case Report ◽  
Primary Care Physicians ◽  
Rare Condition ◽  
Index Patient ◽  
Management Algorithm ◽  
Global Pandemic ◽  
Surgical Expertise ◽  
Systemic Symptoms ◽  
Specific Symptoms

Adrenal cysts are rare lesions that could be epithelial, endothelial, parasitic or haemorrhagic[1], as well as pseudocysts. Haemorrhagic adrenal cysts are extremely rare and are often asymptomatic, so diagnosis can be really challenging. This can prove really difficult for primary care physicians who are often the frontline clinicians these patients tend to present to. They are usually benign lesions and do not often cause mortality if detected early and prompt surgery is done, as was the case with the patient in our case report[4]. When they do become symptomatic, they can present with different systemic symptoms as documented in literature, including in our case report[2,4]. Diagnosis is usually through Ultrasound and CT Scan and management is largely laparoscopic or open excision depending on the size of the lesion, surgical expertise and local protocol. Most patients make full recovery and mortality is extremely low [3]. The aim of this review is to provide a broader overview of the subject, highlight salient points in several studies relating to haemorrhagic cysts, provide an up to date follow up information on the index patient in our case report and to explore possible areas for future study [4,6]. This review also includes a suggested management algorithm and intends to emphasize the fact that patients who present in primary, urgent or emergency care settings with persistent non-specific symptoms should be investigated for rare diseases.

CONGENITAL TRUE COMPLETE SYMPHALANGISM OF ALL PROXIMAL INTERPHALANGEAL JOINTS OF HANDS WITH CARPAL ANOMALIES: A CASE REPORT

Hand Surgery ◽  
2001 ◽  
Vol 06 (02) ◽  
pp. 223-226 ◽  
Author(s):  
Ibrahim Tuncay ◽  
Fuat Akpinar ◽  
Nihat Tosun
Keyword(s):  
Case Report ◽  
Rare Condition ◽  
Clinical Problem ◽  
Carpal Bones ◽  
Skeletal Survey ◽  
Skeletal Deformities ◽  
Type Iii ◽  
Congenital Fusion

Symphalangism is a rare condition which manifests in either PIP or DIP joint congenital fusion. Symphalangism may be with some other skeletal deformities. In our case, all PIP joints of both hands were fused with bilateral hypoplasia of carpal bones and Minaar type III lunatotriquetral coalition congenitally. No motion was detected in PIP joints with absence of cutaneous creases over all PIP joints. Radiologically, carpal hypoplasia and lunatotriquetral coalition were seen in all fingers with the absence of PIP joints. The patient's skeletal survey revealed no other pathology. He had no complaints related to his hands. So, regular follow-up was recommended. This pathology was presented as rarely observed although clinical problem is usually not so much.

scholarly journals Chondroblastoma of thoracic vertebra in young adult causing paraparesis

2017 ◽  
Vol 31 (3) ◽  
pp. 335-338
Author(s):  
Pramod J. Giri ◽  
Vaibhav S. Chavan
Keyword(s):  
Case Report ◽  
World Literature ◽  
Clinical Presentation ◽  
Rare Condition ◽  
Thoracic Vertebra ◽  
Complete Excision ◽  
The World ◽  
Posterior Element ◽  
Almost All

Abstract Chondroblastoma of spine is very rare condition. To best of our knowledge, fewer than 30 cases have been reported in the world literature. Almost all of them involved both anterior & posterior component of vertebra. There are only few reports with isolated posterior element involvement. Clinical presentation of paraparesis because of vertebral chondroblastoma is very rare. This case report presents 17 yr old male with chondroblastoma involving posterior thoracic vertebra presenting with quadriparesis which improved after successful treatment. Early diagnosis and complete excision with periodic follow up is necessary for treatment of this disease.

scholarly journals Mesothelioma with Nonbacterial Thrombotic Endocarditis: A Case Report

2021 ◽  
Vol 59 (243) ◽  
pp. 1170-1173
Author(s):  
Avatar Verma ◽  
Narendra Bhatta ◽  
Deebya Raj Mishra ◽  
Achyut Bhakta Acharya ◽  
Rejina Shahi ◽  
...  
Keyword(s):  
Case Report ◽  
Cardiac Failure ◽  
Disseminated Intravascular Coagulation ◽  
Malignant Neoplasm ◽  
Rare Condition ◽  
Clinical Suspicion ◽  
Pleural Mesothelioma ◽  
Rare Association ◽  
Autoimmune Conditions ◽  
Nonbacterial Thrombotic Endocarditis

Non-bacterial thrombotic endocarditis is a rare condition characterized by noninfectious vegetation on cardiac valves which are often associated with malignancy. It often presents with features of embolism rather than cardiac failure. These are usually seen in autoimmune conditions, disseminated intravascular coagulation, malignancy of gut and lung but has also been reported in other malignancies as well. This entity is rare but one must have a clinical suspicion of the disease especially in a patient suffering from malignancy presenting with the embolic phenomenon. In this report, we are presenting a case of non-bacterial thrombotic endocarditis in an inpatient with pleural mesothelioma, a rare malignant neoplasm arising from pleura in a 35 years old mason, and a rare association as well.

Nivolumab induced hypophysitis in an advanced RCC patient

2022 ◽  
pp. 107815522110722
Author(s):  
Merve Korkmaz Yilmaz ◽  
Ilkay Gulturk ◽  
Seher Yildiz Tacar ◽  
Mesut Yilmaz
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Immune Checkpoint Inhibitors ◽  
Checkpoint Inhibitors ◽  
Rare Condition ◽  
Oral Route ◽  
Clinical Suspicion ◽  
High Dose ◽  
Hormonal Profile ◽  
High Degree

Introduction: Immune checkpoint inhibitors (ICIs) are being commonly used to treat solid tumours such as renal cell carcinoma. Hypophysitis is an acute or chronic inflammation of the pituitary gland and nivolumab or pembrolizumab induced hypophysitis is markedly lower compared to ipilimumab. Case report: We present a novel case of a patient with mRCC who was diagnosed with nivolumab induced hypophysitis based on clinical suspicion due to his hormonal profile and a range of symptoms that he developed during nivolumab immunotherapy. Management and outcome: He was treated with high dose of hydrocortisone administered intravenously, subsequently changed to the oral route and physiologic dose. Discussion: Nivolumab induced hypophysitis is a rare condition that usually presents with fewer symptoms. High degree of clinical suspicion and a multidisciplinary team required to diagnose and treat such cases.

Pregnancy a short time after multimodal therapy for bilateral breast cancer: A case report and review of literature

2010 ◽  
Vol 17 (4) ◽  
pp. 440-443 ◽  
Author(s):  
Timur Koca ◽  
Zuleyha Akgun ◽  
Serap Baskaya Yucel ◽  
Nihal Zerman Dag ◽  
Mehmet Teomete
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Multimodal Therapy ◽  
Bilateral Breast Cancer ◽  
Rare Condition ◽  
Review Of Literature ◽  
Short Time

Pregnancy occurring after multimodal therapy in a woman with breast cancer with a 1-year follow-up period is a relatively rare condition and has been defined as pregnancy-associated breast cancer. A patient can become pregnant after chemotherapy for breast cancer while she is on tamoxifen. However, the effects of tamoxifen on fetus and on the course of the pregnancy are still unknown. Here, we present a 39-year-old woman treated with chemotherapy and radiotherapy for bilateral breast cancer, and who became pregnant while taking tamoxifen.

scholarly journals Management guidelines for amelogenesis imperfecta: a case report and review of the literature

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
M. Roma ◽  
Puneet Hegde ◽  
M. Durga Nandhini ◽  
Shreya Hegde
Keyword(s):  
Case Report ◽  
Treatment Plan ◽  
Rare Condition ◽  
Amelogenesis Imperfecta ◽  
Radiographic Findings ◽  
Case Presentation ◽  
Management Guidelines ◽  
Dental Tissues ◽  
Entire Treatment

Abstract Background Rehabilitation of the entire dentition with amelogenesis imperfecta (AI) tends to pose a great challenge to the clinician. Most of the cases of amelogenesis imperfecta are reported to be associated with skeletal and dental deformities which results in severe sensitivity of the dental tissues. Case presentation This clinical case report marks out the total restoration of the oral condition of a young Indian patient diagnosed with the hypoplastic type of amelogenesis imperfecta. Fixed metal ceramic prosthesis were planned to strengthen the masticatory activity, aesthetics, to banish the dental sensitivity and to build up the general persona of the patient. The patient was followed-up at 6 months, 1 year and 2 years intervals. Functional and esthetic impairment was not visible after the follow up period and the treatment outcome was successful. The entire treatment plan was intended to enhance the functional, esthetic and the masticatory component of the occlusal architecture. Conclusion This case report details the presentation, characteristic radiographic findings, and management of a patient with an extremely rare condition of amelogenesis imperfecta.

scholarly journals Abdominal Viscera Migration Performing Hemodynamic Instability after Esophagectomy: A Case Report

2021 ◽  
pp. 1-6
Author(s):  
Ian Torres de Lima ◽  
Edno Tales Bianchi ◽  
Gabriel Lunardi Aranha ◽  
Beatriz Camargo Azevedo ◽  
Guilherme Naccache Namur ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Case Report ◽  
Minimally Invasive ◽  
Surgical Techniques ◽  
Rare Condition ◽  
Hemodynamic Instability ◽  
Minimally Invasive Surgical ◽  
Late Postoperative Period ◽  
Made In

Hiatal hernia is a rare postoperative complication of esophagectomy in the treatment of esophageal cancer. Although rare, its incidence increased after the establishment of minimally invasive surgical techniques. The patient is usually oligosymptomatic, and the diagnosis is made in the late postoperative period, during outpatient follow-up. The initial presentation of hiatus hernia with hemodynamic instability is a rare condition that has never been described in the literature before. In the following report, we address the clinical picture, diagnosis, and treatment for this condition, discussing the main nuances of the literature.

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