Vitamin D Status and Resting Metabolic Rate May Modify through Expression of Vitamin D Receptor and Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene in Overweight and Obese Adults

2017 ◽  
Vol 72 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Seyedeh Forough Sajjadi ◽  
Khadijeh Mirzaei ◽  
Leila Khorrami-Nezhad ◽  
Zhila Maghbooli ◽  
Seyed Ali Keshavarz
Keyword(s):  
Vitamin D ◽  
Body Weight ◽  
Metabolic Rate ◽  
Resting Metabolic Rate ◽  
Fat Free Mass ◽  
Peroxisome Proliferator ◽  
Vitamin D Status ◽  
Obese Adults ◽  
Peroxisome Proliferator Activated Receptor ◽  
The Relationship

Background: Resting metabolic rate (RMR) used to prognosticate and measure the amount of energy required. Vitamin D is known as a new predictor of RMR. The aim of this study is to investigate the relationship between vitamin D effects on RMR in connection with the vitamin D receptor (VDR) and peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) gene expression. Methods: We enrolled 298 overweight and obese adults in this cross-sectional study. Body mass index (BMI), fat mass, fat-free mass, insulin level, visceral fat, and vitamin D status were assessed. RMR was measured by means of indirect calorimetry. The real-time polymerase chain reaction using specific primer pairs for VDR and PGC-1α was performed. Results: There were significant differences in terms of fat free mass, fat percentage, insulin levels, RMR/kg body weight, and RMR/BMI, VDR, and PGC-1α among participants were categorized based on the vitamin D status. But after using general linear model for adjusting, all significant results missed their effectiveness except RMR/kg body weight and VDR. Linear regression analysis used to show the mediatory role of VDR and PGC-1α on the RMR/kg body weight and vitamin D status relationship. Our results showed that VDR had a mediatory effect on the relationship between RMR/kg body weight and vitamin D status (β = 0.38, 95% CI –0.48 to 1.60; β = –1.24, 95% CI –5.36 to 1.70). However, PGC-1α did not affect the relationship between RMR/kg body weight and vitamin D status (β = 0.50, 95% CI = –0.02 to 3.42; β = 0.59, 95% CI 0.14–3.90). Conclusion: Our study showed the mediatory effect of VDR gene expression in the association of 25(OH)2D plasma levels and resting metabolic rate among obese individuals.

Physiological Effects of Weight Cycling in Female Lightweight Rowers

1993 ◽  
Vol 18 (3) ◽  
pp. 291-303 ◽  
Author(s):  
Linda J. McCargar ◽  
Deanna Simmons ◽  
Neil Craton ◽  
Jack E. Taunton ◽  
C. Laird Birmingham
Keyword(s):  
Body Weight ◽  
Metabolic Rate ◽  
Resting Metabolic Rate ◽  
Metabolic Changes ◽  
Fat Free Mass ◽  
Control Group ◽  
Weight Cycling ◽  
Weight Fluctuation ◽  
Healthy Female ◽  
History Of

Repeated cycles of weight loss and regain are referred to as weight cycling. It is a practice of many athletes who must achieve a low body weight. The purpose of this study was to determine whether a history of weight cycling results in sustained metabolic changes. Healthy female rowers with a history of dieting and weight fluctuation (n = 7) were compared to a control group of rowers who had never dieted (n = 7). Anthropometric and metabolic measurements were done at pre-, peak, and off-season during a 1-year period. At peak season the weight cyclers restricted their food intake and lost 4.2 ± 1.8 kg, and subsequently regained 4.0 ± 2.1 kg in the off-season. This was different from the controls (p =.003), who maintained a stable body weight at all times. No other group differences were observed. Resting metabolic rate (RMR) and triiodothyronine (T3) changed with time (p =.001, p =.000, respectively) in both groups, which appeared to reflect changes in fat free mass (FFM), not body weight. Long-term metabolic changes were not observed in these athletes. Key words: weight cycling, metabolic rate, body composition, rowers

Lack of a relationship between vitamin D status and resting metabolic rate in Iranian adults

2020 ◽  
Author(s):  
Mojdeh Ebaditabar ◽  
Nadia Babaei ◽  
Samira Davarzani ◽  
Hossein Imani ◽  
Mario J. Soares ◽  
...  
Keyword(s):  
Vitamin D ◽  
Metabolic Rate ◽  
Resting Metabolic Rate ◽  
Vitamin D Status

scholarly journals Ketogenic Diet-Induced Weight Loss is Associated with an Increase in Vitamin D Levels in Obese Adults

Molecules ◽  
2019 ◽  
Vol 24 (13) ◽  
pp. 2499 ◽  
Author(s):  
Maria Perticone ◽  
Raffaele Maio ◽  
Angela Sciacqua ◽  
Edoardo Suraci ◽  
Angelina Pinto ◽  
...  
Keyword(s):  
Vitamin D ◽  
Weight Loss ◽  
Ketogenic Diet ◽  
Fat Mass ◽  
Metabolic Diseases ◽  
Strong Association ◽  
Fat Free Mass ◽  
Vitamin D Status ◽  
Obese Adults ◽  
Vitamin D Levels

Vitamin D is an important micronutrient involved in several processes. Evidence has shown a strong association between hypovitaminosis D and cardio-metabolic diseases, including obesity. A ketogenic diet has proven to be very effective for weight loss, especially in reducing fat mass while preserving fat-free mass. The aim of this study was to investigate the effect of a ketogenic diet-induced weight loss on vitamin D status in a population of obese adults. We enrolled 56 obese outpatients, prescribed with either traditional standard hypocaloric Mediterranean diet (SHMD) or very low-calorie ketogenic diet (VLCKD). Serum 25(OH)D concentrations were measured by chemiluminescence. The mean value of serum 25-hydroxyvitamin D (25(OH)D) concentrations in the whole population at baseline was 17.8 ± 5.6 ng/mL, without differences between groups. After 12 months of dietetic treatment, in VLCKD patients serum 25(OH)D concentrations increased from 18.4 ± 5.9 to 29.3 ± 6.8 ng/mL (p < 0.0001), vs 17.5 ± 6.1 to 21.3 ± 7.6 ng/mL (p = 0.067) in the SHMD group (for each kilogram of weight loss, 25(OH)D concentration increased 0.39 and 0.13 ng/mL in the VLCKD and in the SHMD groups, respectively). In the VLCKD group, the increase in serum 25(OH)D concentrations was strongly associated with body mass index, waist circumference, and fatty mass variation. In a multiple regression analysis, fatty mass was the strongest independent predictor of serum 25(OH)D concentration, explaining 15.6%, 3.3%, and 9.4% of its variation in the whole population, in SHMD, and VLCKD groups, respectively. We also observed a greater reduction of inflammation (evaluated by high-sensitivity C reactive protein (hsCRP) values) and a greater improvement in glucose homeostasis, confirmed by a reduction of HOMA values, in the VLCKD versus the SHMD group. Taken together, all these data suggest that a dietetic regimen, which implies a great reduction of fat mass, can improve vitamin D status in the obese.

Weight change adjusted equations for assessing resting metabolic rate in overweight and obese adults

2021 ◽  
Author(s):  
Moran Nachmani ◽  
Yair Lahav ◽  
Aviva Zeev ◽  
Liza Grosman-Rimon ◽  
Sigal Eilat-Adar
Keyword(s):  
Metabolic Rate ◽  
Weight Change ◽  
Resting Metabolic Rate ◽  
Obese Adults

The Relationship of Mode and Intensity of Training on Resting Metabolic Rate in Women

2001 ◽  
Vol 11 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Heidi K. Byrne ◽  
Jack H. Wilmore
Keyword(s):  
Metabolic Rate ◽  
Resting Metabolic Rate ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Women Subjects ◽  
Present Cross Sectional Study ◽  
Significant Difference ◽  
Level Of Training ◽  
The Relationship ◽  
Aerobically Trained

The present cross-sectional study was designed to investigate the relationship between exercise training and resting metabolic rate (RMR). The focus of this investigation was to compare RMR in aerobically trained (AT), resistance trained (RT), and untrained (UNT) women. Subjects were also classified as highly trained (HT), moderately trained (MT), or untrained (UNT) in order to examine the relationship between RMR and level of training. Sixty-one women between the ages of 18 and 46 years volunteered to serve as subjects in this study. Each subject completed measurements of body composition, maximal oxygen uptake (V̇O2max), and two consecutive measurements of RMR. The data presented show that there was no significant difference in resting metabolic rate between resistance-trained, aerobically trained, and control subjects. However, when grouped by intensity of training, there was a trend for an increased resting metabolic rate (kcal/day) in the highly trained subjects, regardless of mode of training.

scholarly journals Weight and skin colour as predictors of vitamin D status: results of an epidemiological investigation using nationally representative data

2016 ◽  
Vol 20 (10) ◽  
pp. 1857-1864 ◽  
Author(s):  
Sonali Rajan ◽  
Tom Weishaar ◽  
Bryan Keller
Keyword(s):  
Vitamin D ◽  
Body Weight ◽  
Skin Colour ◽  
Vitamin D Status ◽  
Epidemiological Investigation ◽  
Dietary Recommendations ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Nationally Representative ◽  
The Impact

AbstractObjectiveCurrent US dietary recommendations for vitamin D vary by age. Recent research suggests that body weight and skin colour are also major determinants of vitamin D status. The objective of the present epidemiological investigation was to clarify the role of age as a predictor of vitamin D status, while accounting for body weight and skin colour, among a nationally representative sample.DesignWe calculated the mean serum 25-hydroxyvitamin D levels for the US population by age and weight, as well as by weight and race/ethnicity group. Multiple regression analyses were utilized to evaluate age and weight as predictors of vitamin D status: serum 25-hydroxyvitamin D levels with age alone, age and body weight, and age, body weight and their two-way interaction were modelled for the entire sample and each age subgroup. Graphical data were developed using B-spline non-linear regression.SettingNational Health and Nutrition Examination Survey (31 934 unweighted cases).SubjectsIndividuals aged 1 year and older.ResultsThere were highly significant differences in mean vitamin D status among US residents by weight and skin colour, with those having darker skin colour or higher body weight having worse vitamin D status. Although a significant factor, the impact of age on vitamin D status was notably less than the impact of body weight.ConclusionsVitamin D status varied predominantly by body weight and skin colour. Recommendations by nutritionists for diet and supplementation needs should take this into account if vitamin D-related health disparities are to be meaningfully reduced across the USA.

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