scholarly journals Serum Cystatin C Predicts AKI and the Prognosis of Patients in Coronary Care Unit: a Prospective, Observational Study

2017 ◽  
Vol 42 (6) ◽  
pp. 961-973 ◽  
Author(s):  
Yugang Hu ◽  
Huilan Liu ◽  
Liguo Du ◽  
Jing Wan ◽  
Xiaoning Li
2009 ◽  
Vol 27 (2) ◽  
pp. 77-82 ◽  
Author(s):  
Faisal Alsayegh ◽  
Mona Al-Rasheed ◽  
Ali Al-Muhaini ◽  
Ekhlas Al-Humoud ◽  
Mona Al-Ostaz ◽  
...  

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 509-P
Author(s):  
JULIA I.F. BRANDA ◽  
BIANCA ALMEIDA ◽  
SANDRA R.G. VIVOLO

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Bertille Elodie Edinga-Melenge ◽  
Adrienne Tchapmi Yakam ◽  
Jobert Richie Nansseu ◽  
Catherine Bilong ◽  
Suzanne Belinga ◽  
...  

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 100
Author(s):  
Asmaa A. Mahmoud ◽  
Doaa M. Elian ◽  
Nahla MS. Abd El Hady ◽  
Heba M. Abdallah ◽  
Shimaa Abdelsattar ◽  
...  

Background: A good survival rate among patients with beta thalassemia major (beta-TM) has led to the appearance of an unrecognized renal disease. Therefore, we aimed to assess the role of serum cystatin-C as a promising marker for the detection of renal glomerular dysfunction and N-acetyl beta-D-glucosaminidase (NAG) and kidney injury molecule 1 (KIM-1) as potential markers for the detection of renal tubular injury in beta-TM children. Methods: This case-control study was implemented on 100 beta-TM children receiving regular blood transfusions and undergoing iron chelation therapy and 100 healthy children as a control group. Detailed histories of complete physical and clinical examinations were recorded. All subjected children underwent blood and urinary investigations. Results: There was a significant increase in serum cystatin-C (p < 0.001) and a significant decrease in eGFR in patients with beta-TM compared with controls (p = 0.01). There was a significant increase in urinary NAG, KIM-1, UNAG/Cr, and UKIM-1/Cr (p < 0.001) among thalassemic children, with a significant positive correlation between serum cystatin-C, NAG and KIM-1 as regards serum ferritin, creatinine, and urea among thalassemic patients. A negative correlation between serum cystatin-C and urinary markers with eGFR was noted. Conclusion: Serum cystatin-C is a good marker for detection of glomerular dysfunction. NAG and KIM-1 may have a predictive role in the detection of kidney injury in beta-TM children.


Sign in / Sign up

Export Citation Format

Share Document