Acute Kidney Injury: Diagnosis and Classification in Adults and Children

2018 ◽  
pp. 1-12 ◽  
Author(s):  
Zaccaria Ricci ◽  
Stefano Romagnoli
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Adults And Children ◽  
Diagnosis And Classification ◽  
Acute Kidney Injury Diagnosis

scholarly journals Chickenpox Mimicking Monkeypox in Adult with Diabetes Mellitus and Acute Kidney Injury: Diagnosis and Management

2021 ◽  
Vol 33 (3) ◽  
pp. 213
Author(s):  
Maya Wardiana ◽  
Rahmadewi Rahmadewi ◽  
Dwi Murtiastutik ◽  
Sawitri Sawitri ◽  
Damayanti Damayanti
Keyword(s):  
Diabetes Mellitus ◽  
Acute Kidney Injury ◽  
Renal Function ◽  
Kidney Injury ◽  
Skin Lesions ◽  
World Health ◽  
Varicella Zoster ◽  
Intravenous Acyclovir ◽  
Acute Kidney Injury Diagnosis ◽  
Health Organization

Background: Chickenpox caused by the varicella-zoster virus (VZV) in diabetes mellitus patients might exhibit similar clinical features with monkeypox, caused by monkeypox virus (MPXV). In May 2019, Singapore notified World Health Organization (WHO) of one laboratory-confirmed case of monkeypox. Considering Singapore is located near Indonesia, awareness about the possibility of an outbreak in Indonesia should be raised. Purpose: To report a case of chickenpox mimicking monkeypox in an adult with diabetes mellitus and acute kidney injury. Case: A 51-year-old male with poorly controlled diabetes mellitus was suspected to have a chickenpox differential diagnosis with monkeypox. His chief complaint was multiple blisters on his body and vomiting. There was a history of feeding a monkey. From dermatological status on facial, trunk, and extremities there were multiple pleomorphic vesicles. Laboratory results showed elevated renal function. Polymerase chain reaction (PCR) examination using VZV as primer revealed a positive result in the range of 810 bp. He was treated with intravenous acyclovir for 3 days and oral acyclovir for 7 days then discharged with improvement in skin lesions and normal renal function. Discussion: Chickenpox in adult and diabetes mellitus patients can give severe clinical manifestation mimicking monkeypox. PCR has a significant role especially when diagnosis could not be established from the physical examination. Acyclovir can be given as the therapy. Conclusion: Adult and poorly controlled diabetes mellitus are important risk factors associated with the severity and complication of chickenpox. A careful diagnostic approach and management are needed.

Loop diuretics for acute kidney injury in adults and children

2012 ◽  
Author(s):  
Watanyu Parapiboon ◽  
Chavasak Kanokkantapong ◽  
Malinee Laopaiboon ◽  
Pisake Lumbiganon ◽  
Apichat Sangchan
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Loop Diuretics ◽  
Adults And Children

Saliva Urea Nitrogen Continuously Reflects Blood Urea Nitrogen after Acute Kidney Injury Diagnosis and Management: Longitudinal Observational Data from a Collaborative, International, Prospective, Multicenter Study

2016 ◽  
Vol 42 (1) ◽  
pp. 64-72 ◽  
Author(s):  
Jochen G. Raimann ◽  
Viviane Calice-Silva ◽  
Stephan Thijssen ◽  
Fabiana Baggio Nerbass ◽  
Marcos A. Vieira ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Blood Urea Nitrogen ◽  
Diagnostic Performance ◽  
Journal Club ◽  
Kidney Injury ◽  
The United States ◽  
Operating Characteristics ◽  
Urea Nitrogen ◽  
Acute Kidney Injury Diagnosis ◽  
Monitoring Treatment

Background: Acute kidney injury (AKI) is a growing global concern and often reversible. Saliva urea nitrogen (SUN) measured by a dipstick may allow rapid diagnosis. We studied longitudinal agreement between SUN and blood urea nitrogen (BUN) and the diagnostic performance of both. Methods: Agreement between SUN and BUN and diagnostic performance to diagnose AKI severity in AKI patients in the United States and Brazil were studied. Bland-Altman analysis and linear mixed effects models were employed to test the agreement between SUN and BUN. Receiver operating characteristics statistics were used to test the diagnostic performance to diagnose AKI severity. Results: We found an underestimation of BUN by SUN, decreasing with increasing BUN levels in 37 studied patients, consistent on all observation days. The diagnostic performance of SUN (AUC 0.81, 95% CI 0.63-0.98) was comparable to BUN (AUC 0.85, 95% CI 0.71-0.98). Conclusion: SUN reflects BUN especially in severe AKI. It also allows monitoring treatment responses. Video Journal Club ‘Cappuccino with Claudio Ronco' at http://www.karger.com/?doi=445041.

scholarly journals A Review on the Application and Limitations of Administrative Health Care Data for the Study of Acute Kidney Injury Epidemiology and Outcomes in Children

2021 ◽  
Vol 9 ◽  
Author(s):  
Emma H. Ulrich ◽  
Gina So ◽  
Michael Zappitelli ◽  
Rahul Chanchlani
Keyword(s):  
Health Care ◽  
Acute Kidney Injury ◽  
Administrative Data ◽  
Health Research ◽  
Validation Studies ◽  
Large Scale ◽  
Kidney Injury ◽  
Process Of Care ◽  
Data Repositories ◽  
Adults And Children

Administrative health care databases contain valuable patient information generated by health care encounters. These “big data” repositories have been increasingly used in epidemiological health research internationally in recent years as they are easily accessible and cost-efficient and cover large populations for long periods. Despite these beneficial characteristics, it is also important to consider the limitations that administrative health research presents, such as issues related to data incompleteness and the limited sensitivity of the variables. These barriers potentially lead to unwanted biases and pose threats to the validity of the research being conducted. In this review, we discuss the effectiveness of health administrative data in understanding the epidemiology of and outcomes after acute kidney injury (AKI) among adults and children. In addition, we describe various validation studies of AKI diagnostic or procedural codes among adults and children. These studies reveal challenges of AKI research using administrative data and the lack of this type of research in children and other subpopulations. Additional pediatric-specific validation studies of administrative health data are needed to promote higher volume and increased validity of this type of research in pediatric AKI, to elucidate the large-scale epidemiology and patient and health systems impacts of AKI in children, and to devise and monitor programs to improve clinical outcomes and process of care.

Diagnosis of oliguria and acute kidney injury

2016 ◽  
Author(s):  
John A. Kellum
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Extracellular Volume ◽  
Kidney Injury ◽  
Clinical Problem ◽  
Clinical Syndrome ◽  
Volume Depletion ◽  
International Consensus ◽  
Tubular Necrosis ◽  
Diagnosis And Classification

Diagnosis and classification of acute pathology in the kidney is major clinical problem. Azotemia and oliguria represent not only disease, but also normal responses of the kidney to extracellular volume depletion or a decreased renal blood flow. Clinicians routinely make inferences about both the presence of renal dysfunction and its cause. Pure prerenal physiology is unusual in hospitalized patients and its effects are not necessary benign. Sepsismay alter renal function without the characteristic changes in urine indices. The clinical syndrome known as acute tubular necrosis does not actually manifest the histological changes that the name implies. Acute kidney injury (AKI) is a term proposed to encompass the entire spectrum of the syndrome from minor changes in renal function to a requirement for renal replacement therapy. Criteria based on both changes in serum creatinine and urine output represent a broad international consensus for diagnosing and staging AKI.

Neonatal Acute Kidney Injury: Diagnosis, Exposures, and Long-term Outcomes

NeoReviews ◽  
2018 ◽  
Vol 19 (6) ◽  
pp. e322-e336
Author(s):  
Jennifer R. Charlton ◽  
Ronnie Guillet
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Long Term Outcomes ◽  
Acute Kidney Injury Diagnosis
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