scholarly journals Bullous Exudative Retinal Detachment after Retinal Pattern Scan Laser Photocoagulation in Diabetic Retinopathy

2017 ◽  
Vol 8 (3) ◽  
pp. 475-481 ◽  
Author(s):  
Shohei Nishikawa ◽  
Hiroshi Kunikata ◽  
Naoko Aizawa ◽  
Toru Nakazawa
Keyword(s):  
Diabetic Retinopathy ◽  
Retinal Detachment ◽  
Laser Photocoagulation ◽  
Standard Treatment ◽  
Case Series ◽  
Exudative Retinal Detachment ◽  
Moderate Number ◽  
Key Points ◽  
Pattern Scan Laser ◽  
Retinal Photocoagulation

Laser retinal photocoagulation is the gold standard treatment for diabetic retinopathy. We describe 3 cases in which bullous exudative retinal detachment (ERD) developed after pattern scan laser photocoagulation (PASCAL) in diabetic retinopathy. ERD spontaneously resolved in all 3 cases with various visual courses. This case series highlights 2 key points: first, ERD can occur regardless of gender, age, glycemic control, or vitreous status and despite a moderate number of laser shots, even with PASCAL; second, ERD in nonvitrectomized eyes may cause irreversible visual loss, even if the ERD resolves within 1 month.

scholarly journals A family with Von Hippel-Lindau disease with different presentations

1970 ◽  
Vol 14 (1) ◽  
pp. 17-24
Author(s):  
Ching-lin Wong ◽  
Ming-Yueh Lee ◽  
R. Sunder ◽  
R. Jamalia ◽  
T.V.N. Karunakar ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Laser Photocoagulation ◽  
Case Series ◽  
Capillary Hemangioma ◽  
Exudative Retinal Detachment ◽  
Fundus Examination ◽  
Von Hippel Lindau ◽  
Retinal Capillary ◽  
Von Hippel Lindau Disease ◽  
Retinal Capillary Hemangioma

Objective: To report three cases of Von Hippel-Lindau (VHL) disease from a family with different presentations.Method: Case series.Results: Case 1, a 14-year-old Malay boy with a history of gradual blurring of vision in both eyes presented with sudden deterioration of right vision. Fundus examination revealed bilateral retinal capillary hemangioma with exudative retinal detachment. His right eye underwent combination therapy of laser photocoagulation, cryotherapy, intravitreal anti-VEGF and photodynamic therapy, but failed to improve vision. His left visiondeteriorated and eventually required surgical intervention. Case 2 was the sister of case 1. She was a 17-year-old Malay girl who presented with sudden onset of left eye pain and redness. Diagnosis of left eye rubeotic glaucoma with closed funnel retinal detachment secondary to a huge retinal hemangioma was made. She underwent left eye external drainage of subretinal fluid plus anterior retinal cryopexy. The rubeotic vessel regressed postoperatively and IOP reduced. Case 3 was the eldest sister of case 1; a 19-year-old Malay girl who came for eye screening after two of her siblings were diagnosed with VHL. She was, however, asymptomatic. Fundus examination revealed right retinal capillary hemangioma. She was treated with laser photocoagulation and her condition remained stable. Systemic investigations identified midline cystic masses in the brain, spine and pancreas. Conclusions: This case series highlight different clinical pictures of Von Hippel-Lindau disease. As marked visual loss is a dreadful sequela of VHL, it is important to screen the family members as early detection and management of ocular and systemic lesions save sight and life.

scholarly journals A case report of ultrasonographic findings in bilateral diffuse Uveal melanocytic proliferation

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jingli Guo ◽  
Wenyi Tang ◽  
Wei Liu ◽  
Min Zhou ◽  
Qing Chang ◽  
...  
Keyword(s):  
Case Report ◽  
Retinal Detachment ◽  
High Frequency ◽  
Ciliary Body ◽  
Case Series ◽  
Ultrasound Biomicroscopy ◽  
The Other ◽  
Exudative Retinal Detachment ◽  
Case Presentation ◽  
Choroidal Nevi

Abstract Background To report undescribed characteristics of patients with bilateral diffuse uveal melanocytic proliferation (BDUMP) on ultrasound biomicroscopy (UBM) and high-frequency B-scan ultrasonography. Case presentation Two of four participants presented with worsening bilateral vision after previously diagnosed primary pulmonary or ovarian carcinoma. The other two patients were diagnosed with lung carcinoma after presentation with BDUMP. All patients had ciliary body nevi-like lesion in combination with iris or ciliary body cysts, and uveal thickening on UBM. Focally elevated choroidal nevi-like lesion and exudative retinal detachment with choroidal thickening were detected with B-scan ultrasonography. Conclusions Our case series demonstrates the uveal characteristics of patients with BDUMP based on high-frequency B-scan ultrasonography and UBM. Ultrasonographic findings are crucial in the diagnosis of BDUMP because it is occult in nature.

scholarly journals Predictive risk factors for exudative retinal detachment after vitrectomy for proliferative diabetic retinopathy

Medicine ◽  
2019 ◽  
Vol 98 (8) ◽  
pp. e14603
Author(s):  
Di-Fang Sun ◽  
Yan-Li Wang ◽  
Bin Wang ◽  
Chun-Ling Xu ◽  
Gong Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Diabetic Retinopathy ◽  
Retinal Detachment ◽  
Proliferative Diabetic Retinopathy ◽  
Exudative Retinal Detachment ◽  
Predictive Risk

Intravitreal Dexamethasone Implant (Ozurdex®) for Exudative Retinal Detachment after Proton Beam Therapy for Choroidal Melanoma

2017 ◽  
Vol 27 (5) ◽  
pp. 596-600 ◽  
Author(s):  
Ariane Malclès ◽  
Anh-Minh Nguyen ◽  
Thibaud Mathis ◽  
Jean-Daniel Grange ◽  
Laurent Kodjikian
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Proton Beam ◽  
Safety Profile ◽  
Choroidal Melanoma ◽  
Case Series ◽  
Proton Beam Therapy ◽  
Exudative Retinal Detachment ◽  
Dexamethasone Implant

Purpose To evaluate the efficacy and safety of intravitreal 0.7-mg dexamethasone implant (DEX-I) (Ozurdex®) in the treatment of extensive exudative retinal detachment (RD) associated with uveal melanoma treated using proton beam therapy (PBT). Methods Data from 10 patients with exudative RD after PBT treated with intravitreal injection of 0.7-mg DEX-I were reviewed retrospectively. The main outcome measures were resolution of exudative RD, visual acuity, and safety profile. Results Mean age was 55.6 years (range 34-85). Mean time between PBT and DEX-I was 12.4 months (range 3-25). Mean follow-up was 9.9 months (range 4-15). Intravitreal Ozurdex® reduced exudative RD in 7 cases (70%) on average 3.1 months after injection with complete resolution of RD in 6 of these (60%). For half of the patients, their level of vision remained stable; the other half experienced a deterioration in visual acuity at the end of follow-up. No adverse effects were observed. Conclusions In this small case series, treatment with intravitreal DEX-I reduced exudative RD in the majority of cases and had an acceptable safety profile.

scholarly journals Bullous X linked retinoschisis: clinical features and prognosis

2017 ◽  
Vol 102 (5) ◽  
pp. 622-624 ◽  
Author(s):  
Anne-Marie Hinds ◽  
Abigail Fahim ◽  
Anthony T Moore ◽  
Sui Chien Wong ◽  
Michel Michaelides
Keyword(s):  
Retinal Detachment ◽  
Age Of Onset ◽  
Case Series ◽  
Peripheral Retina ◽  
Exudative Retinal Detachment ◽  
Retrospective Case ◽  
Tertiary Centre ◽  
Unilateral Case ◽  
The Mean

Background/AimsA subset of patients with X linked retinoschisis (XLRS) have bullous schisis cavities in the peripheral retina. This study describes the characteristics and prognosis of the bullous form of XLRS.MethodsA retrospective case series was performed of nine patients with molecularly proven bullous XLRS seen at a single tertiary centre.ResultsAll cases of bullous peripheral schisis were bilateral, with one unilateral case at presentation which developed into bilateral bullous schisis over time. The mean age of onset was 1.9 years (range: 1 month–7 years, SD: 2.1 years) and at clinical diagnosis was 5.9 years (range: 1 month–27 years, SD: 9.0 years). Mean follow-up was 11 years (range: 6 months–36 years, SD: 10.8 years). Strabismus was the most common presentation (n=7). Other presenting complaints included decreased vision, floaters and an irregularly shaped pupil. The most frequently associated ocular features were strabismus (100%), vitreous haemorrhage (4/18 eyes, 22%), nystagmus (2/9, 22%) and persistent fetal vasculature (1/18, 6%). Localised tractional detachment was seen in 2/18 (11%) eyes, total detachment that underwent surgical repair in 1/18 (6%) and pigmented demarcation lines in a further 22% of the eyes. There was one eye with exudative retinal detachment.ConclusionIn XLRS, bullous schisis may be congenital or develop soon after birth and most commonly presents with strabismus. Cases may be complicated by some form of retinal detachment, which may be tractional or a Coats-like exudative detachment.

scholarly journals Retinal detachment in retinitis pigmentosa

2020 ◽  
Vol 5 (1) ◽  
pp. e000454 ◽  
Author(s):  
Weng Onn Chan ◽  
Nicholas Brennan ◽  
Andrew R Webster ◽  
Michel Michealides ◽  
Mahiul M K Muqit
Keyword(s):  
Retinal Detachment ◽  
Retinitis Pigmentosa ◽  
Surgical Outcomes ◽  
Case Series ◽  
Exudative Retinal Detachment ◽  
Retrospective Case ◽  
Full Spectrum ◽  
Natural Progression ◽  
Electronic Database Search

ObjectiveRetinitis pigmentosa-related retinal detachment (RPRD) is rare, and the full spectrum of retinal complications is not well defined. To describe the types of retinal detachment in patients with retinitis pigmentosa and the surgical outcomes of RPRD.MethodsThis is a non-comparative, retrospective case series. An electronic database search was performed using Moorfields OpenEyes electronic health records. We identified 90 patients with RPRD between January 2000 and August 2017. Main outcome and measures are visual acuity (VA), surgical outcomes and classification of RPRD.ResultsOf the 90 patients/detachments, 61 (67.8%) were rhegmatogenous retinal detachment (RRD), 19 (21.1%) were exudative, 3 (3.3%) were tractional retinal detachment (TRD) and 7 (7.8%) had combined. 37.5% (9/24) of patients with exudative retinal detachment were treated with either cryotherapy or laser, and one patient underwent vitrectomy for vitreous haemorrhage. 56/90 patients underwent surgical intervention. Nine patients presented late and were deemed inoperable (two exudative and seven RRD). Of the RRD patients with full operative record, the primary attachment rate was 76.2% (16/21) and final reattachment rate was 85.7% (18/21) over a mean 15.4-year follow-up period. Mean VA for RRD surgery improved from 6/190 (1.51 logMAR) to 6/120 (1.31 logMAR) (p=0.194). In the TRD group, the mean VA was 6/300 (1.66 logMAR) at baseline and improved after surgery to 6/48 (0.90 logMAR) (p=0.421).ConclusionsWe demonstrated a final reattachment rate of 85.7% with a trend toward better vision following intervention for patients with RPRD. However, the final long-term vision may be poor due to the natural progression of retinitis pigmentosa-associated macular degeneration.

scholarly journals Intravitreal Bevacizumab (Avastin) for Diabetic Retinopathy: The 2010 GLADAOF Lecture

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
J. Fernando Arevalo ◽  
Juan G. Sanchez ◽  
Andres F. Lasave ◽  
Lihteh Wu ◽  
Mauricio Maia ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Laser Photocoagulation ◽  
Case Series ◽  
Intravitreal Bevacizumab ◽  
Panretinal Photocoagulation ◽  
Insulin Administration ◽  
Tractional Retinal Detachment ◽  
Selective Therapy ◽  
Vitrectomy Surgery

This paper demonstrates multiple benefits of intravitreal bevacizumab (IVB) on diabetic retinopathy (DR) including diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) at 24 months of followup. This is a retrospective multicenter interventional comparative case series of intravitreal injections of 1.25 or 2.5 mg of bevacizumab for DME, PDR without tractional retinal detachment (TRD), and patients who experienced the development or progression of TRD after an intravitreal injection of 1.25 or 2.5 mg of bevacizumab before vitrectomy for the management of PDR. The results indicate that IVB injections may have a beneficial effect on macular thickness and visual acuity (VA) in diffuse DME. Therefore, in the future this new therapy could complement focal/grid laser photocoagulation in DME. In PDR, this new option could be an adjuvant agent to panretina photocoagulation so that more selective therapy may be applied. Finally, TRD in PDR may occur or progress after IVB used as an adjuvant to vitrectomy. Surgery should be performed 4 days after IVB. Most patients had poorly controlled diabetes mellitus associated with elevated HbA1c, insulin administration, PDR refractory to panretinal photocoagulation, and longer time between IVB and vitrectomy.

scholarly journals A Case Series of Resolving Vitreous Haemorrhage in the Setting of Diabetic Retinopathy

2019 ◽  
Vol 2 (2) ◽  
pp. 11-26
Author(s):  
Ronald Y. Tiu ◽  
Eleonore B. Iguban ◽  
Milagros H. Arroyo
Keyword(s):  
Diabetic Retinopathy ◽  
Cellular Response ◽  
Posterior Vitreous Detachment ◽  
Case Series ◽  
Vitreous Hemorrhage ◽  
Collagen Matrix ◽  
Membrane Formation ◽  
Pan Retinal Photocoagulation ◽  
Old Females ◽  
Retinal Photocoagulation

This case series presents 2 patients (67 and 58 year old females) with resolving vitreous hemorrhage in the setting of diabetic retinopathy. Both patients had around 50% of the retina still visible and the hemorrhage was confined at the posterior vitreous cavity near the retina, hence, a partial pan retinal photocoagulation (PRP) was feasibly applied. On B-scan, both cases showed a liquified vitreous with posterior vitreous detachment (PVD). For both patients, vitreous hemorrhage resolution occurred at less than 4 months from onset and consequently PRP was completed. Vitreous hemorrhage differs with bleeding in other tissues due to the presence of vitreous collagen matrix which promotes rapid clotting and hinders resolution of hemorrhage by preventing passive diffusion and delay in inflammatory cellular response. The prognosis for clearing hemorrhage was better when the fundus reflex was brighter and the retina adjacent to the ora serrata was visible. Clearing occurred sooner when hemorrhage was retrohyaloid rather than in the vitreous gel. In diabetic eye, the vitreous undergoes metabolic derangements resulting in premature liquefaction and abnormal vitreoretinal adhesion leading to traction and membrane formation. Partial PVD has also been associated with higher rate of diabetic retinopathy progression since it serves as scaffold for growth of neovascular tufts.

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