scholarly journals Impact of Body Mass Index on Early Postoperative and Long-Term Outcome after Rectal Cancer Surgery

2017 ◽  
Vol 33 (5) ◽  
pp. 373-382 ◽  
Author(s):  
Bernhard Gebauer ◽  
Frank Meyer ◽  
Henry Ptok ◽  
Ralf Steinert ◽  
Ronny Otto ◽  
...  
2013 ◽  
Vol 15 (4) ◽  
pp. 463-469 ◽  
Author(s):  
Q. Denost ◽  
L. Quintane ◽  
E. Buscail ◽  
M. Martenot ◽  
C. Laurent ◽  
...  

2004 ◽  
Vol 92 (2) ◽  
pp. 217-224 ◽  
Author(s):  
A. Wibe ◽  
M. T. Eriksen ◽  
A. Syse ◽  
S. Tretli ◽  
H. E. Myrvold ◽  
...  

2016 ◽  
Vol 94 (8) ◽  
pp. 442-452
Author(s):  
Héctor Ortiz ◽  
Antonio Codina ◽  
Miguel Á. Ciga ◽  
Sebastiano Biondo ◽  
José M. Enríquez-Navascués ◽  
...  

2016 ◽  
Vol 14 (10) ◽  
pp. 1-5
Author(s):  
Ali Solmaz ◽  
Osman Gülçiçek ◽  
Elif Binboğa ◽  
Aytaç Biricik ◽  
Candaş Erçetin ◽  
...  

2019 ◽  
Author(s):  
Zhao Lei ◽  
Wang Jian Gang ◽  
Zheng Xing ◽  
Yu Xin

Abstract Background : To investigate the influence of body mass index (BMI) on the short-term and long-term outcome s including disease free survival (DFS) and overall survival (OS) rate in patients with liver carcinoma who underwent laparoscopic hepatectomy (LH) as primary treatment.Methods: Data were collected from 137 patients with liver carcinoma who underwent attempted LH between August 2003 and April 2014. Patients were classified into three groups depending on their BMI according to the WHO’s definition of obesity for Asia-Pacific region: underweight (BMI< 18.5kg/ m 2 , Group1), normal (18.5≤BMI< 23kg/m 2, Group2), overweight (BMI≥ 23kg/m 2, Group3) respectively. Short-term and long-term outcome s including overall survival (OS) and disease free survival (DFS) were compared across the BMI categories.Results: Of the 137 patients, 14 were underweight, 65 were normal weight, and 58 were overweight. The overall conversion rate of 137 patients was 20.44 %. Conversion rate in the three groups was 14.29%, 21.54% and 20.69 % (P=0.8284). The median follow-up duration was 26 months , 30 months , and 28 months, respectively. The mean postoperative hospital stay in the three groups were comparable (10.85±4.04, 11.57±5.56 , and 10.88±5.70, P=0.76). The complications rate was much higher in Group 1 (42.85%) than that in Group 2 and Group 3 (20.08% and 17.2%, P=0.048). Underweight patients were more likely to develop grade III or higher postoperative complications ( Clavien-Dindo classification ) as compared to normal and overweight patients (P=0.042). Overweight patients had a longer 3- and 5-years DFS (41.4%, 36.2%) than those for underweight (21.4%, 14.3%) and normal weight (28.1%, 21.9%) patients (P=0.048, and 0.025). Overweight patients had a longer 5-years OS (44.8%) than those for underweight (28.6%) and normal weight (28.0%) patients (P=0.043).Conclusions : Being underweight was associated with an increased perioperative complication and being overweight has a better 3-, 5-years DFS and 5-years OS than those in under and normal weight patients with liver carcinoma who underwent LH. Key Word s: body mass index, liver carcinoma, Prognosis, laparoscopic hepatectomy


2015 ◽  
Vol 9 (4) ◽  
pp. e122
Author(s):  
Konstantinos Tziomalos ◽  
Stella Bouziana ◽  
Marianna Spanou ◽  
Stavroula Kostaki ◽  
Maria Papadopoulou ◽  
...  

Cancers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 609 ◽  
Author(s):  
Kalb ◽  
Langheinrich ◽  
Merkel ◽  
Krautz ◽  
Brunner ◽  
...  

Background: Excess bodyweight is known to influence the risk of colorectal cancer; however, little evidence exists for the influence of the body mass index (BMI) on the long-term outcome of patients with rectal cancer. Methods: We assessed the impact of the BMI on the risk of local recurrence, distant metastasis and overall—survival in 612 patients between 2003 and 2010 after rectal cancer diagnosis and treatment at the University Hospital Erlangen. A Cox-regression model was used to estimate the hazard ratio and multivariate risk of mortality and distant-metastasis. Median follow up-time was 58 months. Results: Patients with obesity class II or higher (BMI ≥ 35 kg/m2, n = 25) and patients with underweight (BMI < 18.5 kg/m2, n = 5) had reduced overall survival (hazard ratio (HR) = 1.6; 95% confidence interval (CI) 0.9–2.7) as well as higher rates of distant metastases (hazard ratio HR = 1.7; 95% CI 0.9–3.3) as compared to patients with normal bodyweight (18.5 ≤ BMI < 25 kg/m2, n = 209), overweight (25 ≤ BMI <30 kg/m2, n = 257) or obesity class I (30 ≤ BMI <35 kg/m2, n = 102). There were no significant differences for local recurrence. Conclusions: Underweight and excess bodyweight are associated with lower overall survival and higher rates of distant metastasis in patients with rectal cancer.


2010 ◽  
Vol 34 (11) ◽  
pp. 2621-2627 ◽  
Author(s):  
B. A. Grotenhuis ◽  
B. P. L. Wijnhoven ◽  
G. J. Hötte ◽  
E. P. van der Stok ◽  
H. W. Tilanus ◽  
...  

2012 ◽  
Vol 142 (5) ◽  
pp. S-1007 ◽  
Author(s):  
Tomohiro Tanaka ◽  
Max Marquez ◽  
George Therapondos ◽  
Nazia Selzner ◽  
Eberhard L. Renner ◽  
...  

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