scholarly journals Evaluation of the Macular Ganglion Cell-Inner Plexiform Layer and the Circumpapillary Retinal Nerve Fiber Layer in Early to Advanced Stages of Glaucoma: Correlation with Central Visual Function and Visual Field Indexes

2017 ◽  
Vol 58 (4) ◽  
pp. 242-242
Author(s):  
Deepti Mittal ◽  
Suneeta Dubey
Keyword(s):  
Visual Field ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Visual Function ◽  
Plexiform Layer ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Advanced Stages

scholarly journals Macular Ganglion Cell–Inner Plexiform Layer Loss Precedes Peripapillary Retinal Nerve Fiber Layer Loss in Glaucoma with Lower Intraocular Pressure

Ophthalmology ◽  
2019 ◽  
Vol 126 (8) ◽  
pp. 1119-1130 ◽  
Author(s):  
Henry N. Marshall ◽  
Nicholas H. Andrew ◽  
Mark Hassall ◽  
Ayub Qassim ◽  
Emmanuelle Souzeau ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Plexiform Layer ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Retinal Nerve Fiber

scholarly journals The Pattern of Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Thickness Changes in Glaucoma

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Jin A Choi ◽  
Hye-Young Shin ◽  
Hae-Young Lopilly Park ◽  
Chan Kee Park
Keyword(s):  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Plexiform Layer ◽  
Mean Deviation ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Advanced Glaucoma ◽  
Retinal Nerve Fiber

Background/Aims. To investigate the patterns of retinal ganglion cell damage at different stages of glaucoma, using the circumpapillary retinal nerve fiber layer (RNFL) and macula ganglion cell-inner plexiform layer (GCIPL) thicknesses. Methods. In 296 eyes of 296 glaucoma patients and 55 eyes of 55 healthy controls, the correlations of mean deviation (MD) with the superior and inferior quadrant RNFL/GCIPL thickness (defined as the average of three superior and inferior sectors, resp.) were analyzed. Results. In early to moderate glaucoma, most of the RNFL/GCIPL thicknesses had significant positive correlations with the MD. In advanced glaucoma, the superior GCIPL thickness showed the highest correlation with MD (r=0.495), followed by the superior RNFL (r=0.452) (all; P<0.05). The correlation coefficient of the inferior RNFL thickness with MD (r<0.471) was significantly stronger in early to moderate glaucoma compared to that in advanced glaucoma (r=0.192; P<0.001). In contrast, the correlations of the superior GCIPL thickness with MD (r=0.452) in advanced glaucoma was significantly stronger compared to that in early to moderate glaucoma (r=0.159; P<0.001). Conclusions. The most preserved region in advanced glaucoma appears to be the superior macular GCIPL, whereas the most vulnerable region for initial glaucoma is the inferior RNFL around the optic disc.

scholarly journals The Effect of LASIK Procedure on Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Thickness in Myopic Eyes

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Maja Zivkovic ◽  
Vesna Jaksic ◽  
Athanassios Giarmoukakis ◽  
Michael Grentzelos ◽  
Marko Zlatanovic ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Plexiform Layer ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Rnfl Thickness ◽  
Significant Difference ◽  
Retinal Nerve Fiber

Purpose. To evaluate the effect of applied suction during microkeratome-assisted laser in situ keratomileusis (LASIK) procedure on peripapillary retinal nerve fiber layer (RNFL) thickness as well as macular ganglion cell-inner plexiform layer (GC-IPL) thickness. Methods. 89 patients (124 eyes) with established myopia range from −3.0 to −8.0 diopters and no associated ocular diseases were included in this study. RNFL and GC-IPL thickness measurements were performed by spectral domain optical coherence tomography (SD OCT) one day before LASIK and at 1 and 6 months postoperatively. Results. Mean RNFL thickness prior to LASIK was 93.86±12.17 μm while the first month and the sixth month postoperatively were 94.01±12.04 μm and 94.46±12.27 μm, respectively. Comparing results, there is no significant difference between baseline, one month, and six months postoperatively for mean RNFL (p>0.05). Mean GC-IPL thickness was 81.70±7.47 μm preoperatively with no significant difference during the follow-up period (82.03±7.69 μm versus 81.84±7.64 μm; p>0.05). Conclusion. RNFL and GC-IPL complex thickness remained unaffected following LASIK intervention.

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