Gender Differences of Nonmotor Symptoms Affecting Quality of Life in Parkinson Disease

2017 ◽  
Vol 17 (6) ◽  
pp. 276-280 ◽  
Author(s):  
Jee-Eun Yoon ◽  
Ji Sun Kim ◽  
Wooyoung Jang ◽  
Jinse Park ◽  
Eungseok Oh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gender Differences ◽  
Parkinson Disease ◽  
Nonmotor Symptoms

Expected Improvement in Sleep Quality and Unexpected Improvement in Severe Nightmares After Deep Brain Stimulation in Parkinson Disease

2020 ◽  
pp. 169-172
Author(s):  
Laurice Yang
Keyword(s):  
Quality Of Life ◽  
Deep Brain Stimulation ◽  
Parkinson Disease ◽  
Brain Stimulation ◽  
Vital Role ◽  
Expected Improvement ◽  
Nonmotor Symptoms ◽  
Blood Pressure Lability ◽  
Deep Brain

Managing nonmotor symptoms plays a vital role in the quality of life of patients with Parkinson disease (PD); however, it has been unclear whether deep brain stimulation (DBS) can improve these symptoms. Evidence about the effects of nonmotor symptoms from DBS is limited and has mostly focused on mood and other psychological concerns. However, nonmotor symptoms involve a large array of issues, such as constipation, urinary issues, blood pressure lability, mood disorder, rapid eye movement disorder, insomnia, and vivid dreams. In some cases, nonmotor symptoms dramatically affect the quality of life and threaten a patient’s independence more than the motor symptoms themselves. This chapter presents a case in which a patient with PD had experienced lifelong nightmares. He underwent DBS surgery, and shortly thereafter, his nightmares had mostly resolved.

Stereotactic Lesion in the Forel's Field H: A 2-Years Prospective Open-Label Study on Motor and Nonmotor Symptoms, Neuropsychological Functions, and Quality of Life in Parkinson Disease

Neurosurgery ◽  
2019 ◽  
Vol 85 (4) ◽  
pp. E650-E659 ◽  
Author(s):  
Fabio Godinho ◽  
Michel Magnin ◽  
Paulo Terzian Filho ◽  
Paul Reis ◽  
Osmar Moraes ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Global Health ◽  
Parkinson Disease ◽  
Rating Scale ◽  
Nonmotor Symptoms ◽  
Neuropsychological Functions ◽  
Forel's Field H

Abstract BACKGROUND Stereotactic lesion in the Forel's field H (campotomy) was proposed in 1963 to treat Parkinson disease (PD) symptoms. Despite its rationale, very few data on this approach have emerged. Additionally, no study has assessed its effects on nonmotor symptoms, neuropsychological functions and quality of life. OBJECTIVE To provide a prospective 2-yr assessment of motor, nonmotor, neuropsychological and quality of life variables after unilateral campotomy. METHODS Twelve PD patients were prospectively evaluated using the Unified Parkinson's Disease Rating Scale (UPDRS), the Dyskinesia Rating Scale and the Parkinson's disease quality of life questionnaire (PDQ39) before campotomy, and after 6 and 24 mo. Nonmotor, neuropsychiatric, neuropsychological and quality of life variables were assessed. The impact of PD on global health was also rated. RESULTS A significant reduction in contralateral rest tremor (65.7%, P < .001), rigidity (87.8%, P < .001), bradykinesia (68%, P < .001) and axial symptoms (24.2%, P < .05) in offmedication condition led to a 43.9% reduction in UPSDRS III scores 2 yr after campotomy (P < .001). Gait improved by 31.9% (P < .05) and walking time to cover 7 m was reduced by 43.2% (P < .05). Pain decreased by 33.4% (P < .01), while neuropsychiatric and neuropsychological functions did not change. Quality of life improved by 37.8% (P < .05), in line with a 46.7% reduction of disease impact on global health (P < .001). CONCLUSION A significant 2-yr improvement of motor symptoms, gait performance and pain was obtained after unilateral campotomy without significant changes to cognition. Quality of life markedly improved in parallel with a significant reduction of PD burden on global health.

scholarly journals Impact of motor and nonmotor symptoms in Parkinson disease for the quality of life: The Japanese Quality-of-Life Survey of Parkinson Disease (JAQPAD) study

2020 ◽  
Vol 419 ◽  
pp. 117172
Author(s):  
Kanako Kurihara ◽  
Ryoko Nakagawa ◽  
Miwako Ishido ◽  
Yoko Yoshinaga ◽  
Jun Watanabe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson Disease ◽  
Nonmotor Symptoms

Characteristic Motor and Nonmotor Symptoms Related to Quality of Life in Drug-Naïve Patients with Late-Onset Parkinson Disease

2018 ◽  
Vol 18 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Hea Ree Park ◽  
Jinyoung Youn ◽  
Jin Whan Cho ◽  
Eung-Seok Oh ◽  
Ji Sun Kim ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson Disease ◽  
Late Onset ◽  
Nonmotor Symptoms ◽  
Drug Naïve ◽  
Characteristic Motor

Association Between Somatization and Nonmotor Symptoms Severity in People With Parkinson Disease

2020 ◽  
Vol 34 (1) ◽  
pp. 60-65 ◽  
Author(s):  
Aranza Polo-Morales ◽  
Ángel Alcocer-Salas ◽  
Mayela Rodríguez-Violante ◽  
Daniella Pinto-Solís ◽  
Rodolfo Solís-Vivanco ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson Disease ◽  
Motor Symptom ◽  
Control Group ◽  
Nonmotor Symptoms ◽  
Symptom Scale ◽  
Cross Sectional ◽  
Movement Disorder Society ◽  
Control Study

Objective: To assess the frequency of somatization and its association with motor, nonmotor symptoms, and quality of life in persons with Parkinson disease (PD). Methods: A cross-sectional case–control study was carried out. Assessments included the List of 90 Symptoms somatic factor (SCL-90-R SOM), Movement Disorder Society Unified Parkinson’s Ratings Scale (MDS-UPDRS), Non-Motor Symptom Scale (NMSS), Montreal Cognitive Assessment (MoCA), and Parkinson Questionnaire-8 (PDQ-8). Results: A total 93 persons with PD and 93 controls were included. Somatization within the PD group was 2 times more frequent compared to the control group (43% vs 21.5%, P = .003). Persons with PD had higher NMSS total scores (48.6 ± 42.6 vs 28.3 ± 30.4, P = .001). Patients with PD with somatization had worst MDS-UPDRS, NMSS, MoCA, and PDQ-8 (all P < .05). Conclusion: Somatization is more frequent in persons with PD compared to healthy controls. Somatization in PD is associated with nonmotor symptoms and worst quality of life.

scholarly journals Drooling, Swallowing Difficulties and Health Related Quality of Life in Parkinson’s Disease Patients

2021 ◽  
Vol 18 (15) ◽  
pp. 8138
Author(s):  
Gladis Yohana Arboleda-Montealegre ◽  
Roberto Cano-de-la-Cuerda ◽  
César Fernández-de-las-Peñas ◽  
Carlos Sanchez-Camarero ◽  
Ricardo Ortega-Santiago
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Duration ◽  
Health Related Quality ◽  
Nonmotor Symptoms ◽  
Related Quality ◽  
Health Related ◽  
Swallowing Difficulties

Background: Parkinson’s disease (PD) is the most common neurodegenerative disorder associated with motor and nonmotor symptoms. Drooling, one of the nonmotor symptoms, can be present in 70–80% of patients with PD. The aim of this paper is to study the characteristics of PD patients with drooling compared to those without in terms of age, gender, disease duration, stage of the disease, swallowing difficulties, and health-related quality of life; methods: a cross-sectional study was conducted. The sample was divided into two groups: PD with drooling (n = 32) and PD without drooling (n = 30). Age, gender, disease duration and Hoehn & Yahr (H & Y) stage, Sialorrhea Clinical Scale for Parkinson’s Disease (SCS-PD), the 10-item Eating Assessment Tool (EAT-10), and the 39-item Parkinson’s Disease Questionnaire (PDQ-39) were compared between groups; Results: 62 individuals with PD, 40 men and 22 women (mean age 73 ± 8 years), were included. Overall, 32 patients reported drooling, and 30 did not exhibit it. The ANCOVA found significant differences between groups for the EAT-10 score (0.83, 95% CI = 5.62–9.03; p = 0.016) and SCS-PD score (1.48, 95% CI = 0.86–6.81; p < 0.001). Analysis of the PDQ-39 scores revealed no significant differences between groups for the PDQ-39 total score (p > 0.057) and in all subscales. The inclusion of gender, age, disease duration, and H & Y as covariates did not influence the results (all p > 0.05). Conclusions: drooling is related to swallowing difficulties assessed with EAT-10 but not with health-related quality of life assessed with PDQ-39 in PD patients with drooling compared to PD patients without it. Age, gender, duration of the disease, and the H & Y state of PD patients with and without drooling seem to be similar.

Sign in / Sign up

Export Citation Format

Share Document