scholarly journals The Bethesda System for Reporting Cervical Cytology: A Historical Perspective

2017 ◽  
Vol 61 (4-5) ◽  
pp. 359-372 ◽  
Author(s):  
Ritu Nayar ◽  
David C. Wilbur
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Research Management ◽  
Cervical Cytology ◽  
Cervical Disease ◽  
Standardized Terminology ◽  
Bethesda System ◽  
The Bethesda System ◽  
Further Development

The aims of The Bethesda System (TBS) were to provide effective communication from the laboratory to the clinical provider; facilitate cytologic-histologic correlation; facilitate research into the epidemiology, biology, and pathology of cervical disease; and provide reproducible and reliable data for national and international statistical analysis comparisons. Dr. Diane Solomon and colleagues' contribution to cervical cancer screening, diagnosis, and management began with the inception and dissemination of TBS for reporting cervical cytology in 1988, as detailed in the accompanying article [Solomon et al.: Acta Cytol 1989;33:567-574]. The significance of TBS for the further development and implementation of standardized terminology in pathology, and the research/management of cervical cancer have continued to evolve over the past three decades. TBS has always been a multidisciplinary effort and acknowledgement needs to be given to several stakeholders who, over the years, have contributed to its success. It has been our privilege and honor to have carried on the legacy of this seminal work, even as molecular methods are being closely integrated into cervical cancer screening, triage, and prevention.

A current applicability of The Bethesda System 2001 in the uterine cervical cancer screening

2011 ◽  
Vol 50 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Takefumi SHIRAYAMA ◽  
Shigeo SEINO ◽  
Noriko KOBAYASHI ◽  
Kouji BANNO ◽  
Takuma FUJII ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Uterine Cervical Cancer ◽  
Bethesda System ◽  
The Bethesda System ◽  
A Current

scholarly journals Asymptomatic Bacterial Vaginosis in Cervical Cytology: A Preliminary Report of Incidental Finding in Routine Cervical Cancer Screening

2020 ◽  
Vol 10 (10) ◽  
pp. 1471-1481
Author(s):  
Fausta Chioma Jacinta Emegoakor ◽  
Okechukwu Charles Okafor ◽  
Omosivie Monica Ugwu ◽  
Ebele Vivien Okolie ◽  
Chinyere Molokwu ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Bacterial Vaginosis ◽  
Cervical Cancer Screening ◽  
Preliminary Report ◽  
Incidental Finding ◽  
Cervical Cytology

scholarly journals HIV status, age at cervical Cancer screening and cervical cytology outcomes in an opportunistic screening setting in Nigeria: a 10-year Cross sectional data analysis

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Jonah Musa ◽  
Chad J. Achenbach ◽  
Charlesnika T. Evans ◽  
Neil Jordan ◽  
Patrick H. Daru ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Cervical Cytology ◽  
Independent Effect ◽  
Opportunistic Screening ◽  
Hiv Status ◽  
Abnormal Cytology ◽  
Cross Sectional ◽  
Abnormal Cervical Cytology

Abstract Background Invasive cervical cancer (ICC) is more prevalent in HIV infected women and occurs at younger median age than in HIV negative women. Organized cervical cancer screening (CCS) is presently lacking in Nigeria, and the age at CCS is not known in this population. We sought to examine the age at CCS, the cytology outcomes and whether outcomes differ by HIV infection status in an opportunistic screening setting. Methods Cross-sectional analysis of data on a sample of women who had received a CCS in an opportunistic screening service in Jos, Nigeria over a 10-year time period (2006–2016). We used logistic regression models to estimate the independent effect of patient-reported HIV and age at CCS and odds ratios for abnormal cytology outcomes adjusting for other covariates. We also assessed the correlation between median age at CCS and severity of abnormal cervical cytology outcomes. Statistical analyses were done on STATA version 14, College Station, Texas, USA. Results In a sample of 14,088, the median age at CCS was 37 years (IQR; 30–45). For HIV infected women vs. uninfected women, CCS occurred at earlier ages (35.0 ± 7.4 vs 38.2 ± 10.2 years, p < 0.001). All women, regardless of HIV status, who completed at least 7 or more years of education were 1.27 to 3.51 times more likely to have CCS before age 35 than women with less education. The predictors of an abnormal cervical cytology outcome at CCS were: age at CCS ≥ 35 (aOR = 3.57; 95% CI: 2.74, 4.64), multiparity ≥5 (aOR = 1.27; 95% CI: 1.03, 1.56), and provider-referral (aOR = 1.34; 95% CI: 1.09, 1.64). Irrespective of reported HIV status, we found a positive correlation between median age at CCS and severity of cytology outcome. Discussion The age at CCS in women who have utilized cervical cancer screening in the study population is relatively late compared to the recommended age by most guidelines from developed settings. Late age at CCS correlates positively with severity of abnormal cytology outcome irrespective of HIV status. More educated women are more likely to have CCS at early age and less likely to have underlying abnormal cytology outcomes.

Cervical Cancer Screening Clinical Practice Guidelines in Oncology

2004 ◽  
Vol 2 (6) ◽  
pp. 570 ◽  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Current Method ◽  
The United States ◽  
Cervical Cytology ◽  
Screening Guidelines ◽  
Incidence And Mortality ◽  
Recent Version ◽  
Cytology Screening

Despite a significant decrease in the incidence and mortality of cervical carcinoma in the United States, 10,520 women are expected to develop the disease in 2004, with 3,900 expected deaths. Because cervical cytology screening is the current method for early detection of this neoplasm, the purpose of the NCCN Cervical Cancer Screening Guidelines is to provide direction for the evaluation and management of cervical cytology. For the most recent version of the guidelines, please visit NCCN.org

scholarly journals Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Pernille Thordal Larsen ◽  
Susanne Fogh Jørgensen ◽  
Mette Tranberg ◽  
Sisse Helle Njor
Keyword(s):  
Cervical Cancer ◽  
Cohort Study ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
False Positive ◽  
Intraepithelial Neoplasia ◽  
Cervical Cytology ◽  
Cervical Intraepithelial Neoplasia Grade ◽  
Screening Participation ◽  
Cancer Screening Participation

Abstract Our aim was to investigate whether receiving a false positive (FP) cervical cytology result affected subsequent cervical cancer screening participation. This Danish nationwide register-based cohort study included 502,380 women aged 22.5–45 attending cervical cancer screening in 2012–2014 with a normal (n = 501,003) or FP (n = 1,377) cytology screening result. A FP result was defined as a cervical cytology showing high grade cytological abnormalities followed by a normal or ‘Cervical Intraepithelial Neoplasia grade 1’ biopsy result. Women were categorized as subsequent participants if they had a cervical cytology within 24–42 months after their last screening or surveillance test. We compared subsequent participation among women with a normal versus a FP result, using odds ratios including 95% confidence intervals. Participation was slightly higher among women with FP results than among women with normal results (71.5% vs. 69.2%, p = 0.058). After adjustment for age and screening history, women with FP results participated significantly more than women with normal results (OR: 1.19, 95% CI 1.06–1.35). Women receiving a FP result did not participate less in subsequent cervical cancer screening than women receiving a normal result. In fact, the use of opportunistic screening seemed to be increased among women receiving a FP result.

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