scholarly journals Greater Real-Life Diagnostic Efficacy of Allergen Molecule-Based Diagnosis for Prescription of Immunotherapy in an Area with Multiple Pollen Exposure

2017 ◽  
Vol 173 (2) ◽  
pp. 93-98 ◽  
Author(s):  
Ulbosin Saltabayeva ◽  
Victoria Garib ◽  
Marina Morenko ◽  
Rafail Rosenson ◽  
Zhanat Ispayeva ◽  
...  
Keyword(s):  
Real Life ◽  
Diagnostic Efficacy ◽  
Pollen Exposure ◽  
Multiple Pollen ◽  
Allergen Molecule

CT-guided percutaneous chest biopsy - diagnostic efficacy and complications: real life study

2019 ◽  
Author(s):  
Margarida Costa e Silva ◽  
Pedro Melo ◽  
Diogo Rocha ◽  
Tiago Pereira ◽  
Ana Oliveira
Keyword(s):  
Real Life ◽  
Diagnostic Efficacy ◽  
Ct Guided ◽  
Life Study ◽  
Real Life Study

scholarly journals Polcalcins as pollen panallergens in allergic rhinitis

2016 ◽  
Vol 6 (21) ◽  
pp. 19-22
Author(s):  
Florin-Dan Popescu ◽  
Mariana Vieru
Keyword(s):  
Allergic Rhinitis ◽  
Calcium Binding ◽  
Allergen Immunotherapy ◽  
Calcium Binding Protein ◽  
Allergen Component ◽  
Allergen Components ◽  
Ef Hand ◽  
Ige Mediated ◽  
Pollen Exposure ◽  
Multiple Pollen

Abstract Polcalcins are highly cross-reactive calcium-binding allergen components specifically expressed in pollen from trees, grasses and weeds. The grass allergen component rPhl p 7, a recombinant non-glycosylated calcium-binding protein of 2-EF-hand type, is the most cross-reactive polcalcin and may be used as a polcalcin biomarker of IgE-mediated hypersensitivity. Polcalcin sensitization, which appears to be linked to geographical factors, level and time of pollen exposure, has to be assessed in allergic rhinitis patients with multiple pollen sensitizations and may be useful for a better targeted prescription of allergen immunotherapy.

scholarly journals Evaluation of Performance of Detection of IgG and IgM Antibody Against Spike Protein of SARS-CoV-2 by a Rapid Kit in a Real-Life Hospital Setting

2021 ◽  
Author(s):  
Monica Irungbam ◽  
Anubhuti Chitkara ◽  
Vijay Kumar Singh ◽  
Subash Chandra Sonkar ◽  
Abhisekh Dubey ◽  
...  
Keyword(s):  
Real Life ◽  
Hospital Setting ◽  
Antibody Test ◽  
Protein S ◽  
Spike Protein ◽  
Diagnostic Efficiency ◽  
Rt Pcr ◽  
Antibody Testing ◽  
Diagnostic Efficacy ◽  
Rapid Antibody

Abstract Background Antibody testing are often used for serosurveillance of COVID-19. ELISA and Chemiluminesence based antibody test are quiet sensitive and specific for such serological testing. Rapid antibody tests are developed and effectively used for this purpose. But their diagnostic efficiency needs to be evaluated. So, the present study was conducted in a dedicated COVID-19 hospital in Delhi, India to evaluate the diagnostic efficacy of a Rapid antibody kit for COVID-19. Material and Method : Sixty COVID-19 confirmed cases by RT-PCR were recruited and categorized as early, intermediate and late cases based on the number of days of their first RT-PCR + ve tests, 20 subjects in each category. Twenty samples from pre-covid era were taken as controls. IgM and IgG antibodies against RBD of spike protein (S) of SARS-CoV2 virus were detected by Rapid antibody test and compared with total antibody against the nucleocapsid (N) antigen of SARS-CoV-2 by Electrochemiluminescence based Immunoassay (ECLIA). Results The detection IgM against Receptor binding domain (RBD) of spike protein by rapid kit was 0-37.5% sensitive and 0-100% specific for diagnosis of SARS-CoV-2 infection. However, efficacy of detection of IgG by rapid kit was 87–89% sensitive and 75–100% specific when compared with total antibody against N antigen measured by ECLIA based immunoassay. Conclusion It can be concluded that detection of IgM against RBD of S protein by rapid kit is not effective but IgG detection can be used as an effective diagnostic tool for SARS-COV-2 infection.

A peek in the micro-sized world: a review of design principles, engineering tools, and applications of engineered microbial community

2020 ◽  
Vol 48 (2) ◽  
pp. 399-409
Author(s):  
Baizhen Gao ◽  
Rushant Sabnis ◽  
Tommaso Costantini ◽  
Robert Jinkerson ◽  
Qing Sun
Keyword(s):  
Microbial Community ◽  
Microbial Communities ◽  
Environmental Remediation ◽  
Real Life ◽  
Design Principles ◽  
Microbial Interactions ◽  
Potential Applications ◽  
New Gene ◽  
Global Biogeochemical Cycles ◽  
Synthetic Microbial Communities

Microbial communities drive diverse processes that impact nearly everything on this planet, from global biogeochemical cycles to human health. Harnessing the power of these microorganisms could provide solutions to many of the challenges that face society. However, naturally occurring microbial communities are not optimized for anthropogenic use. An emerging area of research is focusing on engineering synthetic microbial communities to carry out predefined functions. Microbial community engineers are applying design principles like top-down and bottom-up approaches to create synthetic microbial communities having a myriad of real-life applications in health care, disease prevention, and environmental remediation. Multiple genetic engineering tools and delivery approaches can be used to ‘knock-in' new gene functions into microbial communities. A systematic study of the microbial interactions, community assembling principles, and engineering tools are necessary for us to understand the microbial community and to better utilize them. Continued analysis and effort are required to further the current and potential applications of synthetic microbial communities.

The Speech-Language Pathologist in the Public Schools: Preparation for Real Life Practices From the Perspective of a Speech-Language Pathology Program Coordinator

2010 ◽  
Vol 11 (2) ◽  
pp. 60-65
Author(s):  
Francine Wenhardt
Keyword(s):  
Public Schools ◽  
School Setting ◽  
Real Life ◽  
Effective School ◽  
Program Coordinator ◽  
Educational Preparation ◽  
The Public ◽  
Speech Language Pathologist ◽  
New Graduate ◽  
Language Pathology

Abstract The speech-language pathologist (SLP) working in the public schools has a wide variety of tasks. Educational preparation is not all that is needed to be an effective school-based SLP. As a SLP currently working in the capacity of a program coordinator, the author describes the skills required to fulfill the job requirements and responsibilities of the SLP in the school setting and advises the new graduate regarding the interview process and beginning a career in the public schools.

541 Tolerability of CHARM-ADDED candesartan in “real-life” patients with advanced chronic heart failure

2006 ◽  
Vol 5 (1) ◽  
pp. 119-119
Author(s):  
M MACDONALD ◽  
N HAWKINS ◽  
M SHAW ◽  
J MCMURRAY ◽  
H DARGIE ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Real Life
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