Nuclear Deoxyribonucleic Acid Determination in Patients with Prostate Carcinomas: Clinical Research and Application

1993 ◽  
Vol 23 (2) ◽  
pp. 64-76 ◽  
Author(s):  
B. Tribukait
Keyword(s):  
Clinical Research ◽  
Deoxyribonucleic Acid ◽  
Prostate Carcinomas ◽  
Nuclear Deoxyribonucleic Acid ◽  
Acid Determination

scholarly journals Nuclear deoxyribonucleic acid polymerases of liver.

1975 ◽  
Vol 250 (20) ◽  
pp. 8179-8183
Author(s):  
WE Lynch ◽  
S Surrey ◽  
I Lieberman
Keyword(s):  
Deoxyribonucleic Acid ◽  
Nuclear Deoxyribonucleic Acid

Nuclear Deoxyribonucleic Acid Content in Inverted Papilloma of the Urothelium

1994 ◽  
Vol 26 (2) ◽  
pp. 149-152 ◽  
Author(s):  
Kazuto Kunimi ◽  
Tadao Uchibayashi ◽  
Torn Hasegawa ◽  
Soo-Woong Lee ◽  
Mitsuo Ohkawa
Keyword(s):  
Acid Content ◽  
Deoxyribonucleic Acid ◽  
Inverted Papilloma ◽  
Nuclear Deoxyribonucleic Acid

Feulgen Microspectrophotometry of Oral Cancer and Leukoplakia

1975 ◽  
Vol 54 (6) ◽  
pp. 1196-1199 ◽  
Author(s):  
John L. Doyle ◽  
John H. Manhold
Keyword(s):  
Cervical Cancer ◽  
Oral Cancer ◽  
Cell Lines ◽  
Acid Content ◽  
Deoxyribonucleic Acid ◽  
Diploid Cell ◽  
Nuclear Deoxyribonucleic Acid

Feulgen microspectrophotometry was performed using the two wavelength method on 33 lesions and showed that five of ten carcinomas and 12 of 16 leukoplakias had diploid cell lines. This correlates well with similar findings in cervical cancer and dysplasia suggesting that changes in nuclear deoxyribonucleic acid content occur quite early in the evolution of cancer.

Wilms Tumors: Relationship of Nuclear Deoxyribonucleic Acid Ploidy to Patient Survival

1987 ◽  
Vol 138 (4 Part 2) ◽  
pp. 974-977 ◽  
Author(s):  
Leslie M. Rainwater ◽  
Yoshio Hosaka ◽  
George M. Farrow ◽  
Stephen A. Kramer ◽  
Panayotis P. Kelalis ◽  
...  
Keyword(s):  
Deoxyribonucleic Acid ◽  
Patient Survival ◽  
Relationship Of ◽  
Nuclear Deoxyribonucleic Acid

Nuclear Deoxyribonucleic Acid Ploidy and Serum Prostate Specific Antigen in Operable Prostatic Adenocarcinoma

1990 ◽  
Vol 144 (2 Part 1) ◽  
pp. 303-306 ◽  
Author(s):  
Ofer Nativ ◽  
Robert P. Myers ◽  
George M. Farrow ◽  
Terry M. Therneau ◽  
Horst Zincke ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Deoxyribonucleic Acid ◽  
Specific Antigen ◽  
Prostatic Adenocarcinoma ◽  
Serum Prostate Specific Antigen ◽  
Nuclear Deoxyribonucleic Acid

Nuclear Deoxyribonucleic Acid Ploidy of Testicular Tumors: Peculiar Features and Clinical Significance

1996 ◽  
Vol 57 (4) ◽  
pp. 203-208 ◽  
Author(s):  
Makoto Suzuki ◽  
Yoshio Hosaka ◽  
Hisashi Matsushima ◽  
Takashi Mizutani ◽  
Kazuki Kawabe
Keyword(s):  
Clinical Significance ◽  
Deoxyribonucleic Acid ◽  
Testicular Tumors ◽  
Nuclear Deoxyribonucleic Acid

Denaturation of deoxyribonucleic acid in situ effect of formaldehyde.

1975 ◽  
Vol 23 (6) ◽  
pp. 431-438 ◽  
Author(s):  
F Traganos ◽  
Z Darzyndiewicz ◽  
T Sharpless ◽  
M R Melamed
Keyword(s):  
Deoxyribonucleic Acid ◽  
Direct Action ◽  
Chromatin Condensation ◽  
Cross Linking ◽  
Dna Denaturation ◽  
Cell Type ◽  
Dna Interactions ◽  
Flow Through ◽  
Nuclear Deoxyribonucleic Acid

In situ denaturation of nuclear deoxyribonucleic acid (DNA) is studied by use of acridine orange to differentially stain native versus denatured DNA, and a flow-through cytofluorometer for measurements of cell fluorescence. Thermal- or acid-induced DNA denaturation is markedly influenced by formaldehyde. Two mechanisms of the formaldehyde action are distinguished. If cells are exposed to the agent during heating, DNA denaturation is facilitated, most likely by the direct action of formaldehyde as a "passive" denaturing agent on DNA. If cells are pretreated with formaldehyde which is then removed, DNA resistance to denaturation increases, presumably due to chromatin cross-linking. It is believed that both effects occur simultaneously in conventional techniques employing formaldehyde to study DNA in situ, and that the extent of each varies with the temperature and cell type (chromatin condensation). Thus, profiles of DNA denaturation of cells heated with formaldehyde do not represent characteristics of DNA denaturation in situ; DNA denaturation under these conditions is modulated by the reactivity of chromatin components with formaldehyde rather than by DNA interactions with the macromolecules of nuclear mileu.

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