Dilemma of Microscopic Lymph Node Metastases in Human Prostate Cancer

1993 ◽  
Vol 24 (2) ◽  
pp. 57-60 ◽  
Author(s):  
P. Ekman
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Node Metastases

A novel mouse model of human prostate cancer to study intraprostatic tumor growth and the development of lymph node metastases

The Prostate ◽  
2018 ◽  
Vol 78 (9) ◽  
pp. 664-675 ◽  
Author(s):  
Johannes Linxweiler ◽  
Christina Körbel ◽  
Andreas Müller ◽  
Markus Hammer ◽  
Christian Veith ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Mouse Model ◽  
Tumor Growth ◽  
Lymph Node Metastases ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Node Metastases

scholarly journals Direct comparison of choline PET/CT and MRI in the diagnosis of lymph node metastases in patients with prostate cancer

Medicine ◽  
2018 ◽  
Vol 97 (50) ◽  
pp. e13344 ◽  
Author(s):  
Shi-ming Huang ◽  
Liang Yin ◽  
Jian-lan Yue ◽  
Yan-feng Li ◽  
Yang Yang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Choline Pet ◽  
Pet Ct ◽  
Node Metastases ◽  
Ct And Mri

Androgen receptor status of lymph node metastases from prostate cancer

The Prostate ◽  
1996 ◽  
Vol 28 (2) ◽  
pp. 129-135 ◽  
Author(s):  
Alfred Hobisch ◽  
Zoran Culig ◽  
Christian Radmayr ◽  
Georg Bartsch ◽  
Helmut Klocker ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Androgen Receptor ◽  
Lymph Node Metastases ◽  
Receptor Status ◽  
Node Metastases

Re: Nationwide prevalence of lymph node metastases in Gleason score 3+3= prostate cancer: authors’ reply

Pathology ◽  
2015 ◽  
Vol 47 (4) ◽  
pp. 394-395
Author(s):  
Weiva Sieh ◽  
Daphne Y. Lichtensztajn ◽  
Scarlett Lin Gomez ◽  
Jen-Jane Liu ◽  
Benjamin I. Chung ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Gleason Score ◽  
Lymph Node Metastases ◽  
Node Metastases

Detection of Lymph Node Metastases in Patients With Prostate Cancer: Comparing Conventional and Digital [18F]-fluorocholine PET-CT Using Histopathology as Reference

2021 ◽  
Author(s):  
Mimmi Bjöersdorff ◽  
Christopher Puterman ◽  
Jenny Oddstig ◽  
Jennifer Amidi ◽  
Sophia Zackrisson ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Lymph Nodes ◽  
Lymph Node Metastases ◽  
Reconstruction Algorithms ◽  
High Risk Prostate Cancer ◽  
Pet Ct ◽  
Risk Prostate Cancer ◽  
Node Metastases

Abstract Background: Positron emission tomography-computed tomography (PET-CT) can be used to detect and stage metastatic lymph nodes in intermediate to high-risk prostate cancer. Improvements to hardware, such as digital technology, and to software, such as reconstruction algorithms, have recently been made. We compared the capability of detecting regional lymph node metastases using conventional and digital silicon photomultiplier (SiPM)-based PET-CT technology for [18F]-fluorocholine (FCH). Extended pelvic lymph node dissection (ePLND) histopathology was used as the reference method.Methods: Retrospectively, a consecutive series of patients with prostate cancer who had undergone staging with FCH PET-CT before ePLND were included. Images were obtained with either a conventional or a SiPM-based PET-CT and compared. FCH uptake in pelvic lymph nodes beyond the uptake in the mediastinal blood pool was considered to be abnormal.Results: One hundred eighty patients with intermediate or high-risk prostate cancer were examined using a conventional Philips Gemini PET-CT (n = 93) between 2015 and 2017 or a digital GE Discovery MI PET-CT (n = 87) from 2017 to 2018. Images that were obtained using the Philips Gemini PET-CT system showed 19 patients (20%) with suspected lymph node metastases compared with 40 patients (46%) using the GE Discovery MI PET-CT. Sensitivity, specificity, and positive and negative predictive value (PPV and NPV) were 0.30, 0.84, 0.47, and 0.72, respectively, for the Philips Gemini and 0.60, 0.58, 0.30, and 0.83, respectively for GE Discovery MI. Area under the curve (AUC) in a receiver operating characteristics (ROC) analysis was similar between the two PET-CT systems (0.58 and 0.58, P = 0.8).Conclusions: A marked difference in sensitivity and specificity was found for the different PET-CT systems, although similar overall diagnostic performance. This is probably due to differences in both hard- and software, including reconstruction algorithms, and should be considered when new technology is introduced.

A Nomogram for Staging of Exclusive Nonobturator Lymph Node Metastases in Men with Localized Prostate Cancer

2007 ◽  
Vol 51 (1) ◽  
pp. 112-120 ◽  
Author(s):  
Alberto Briganti ◽  
Felix K.-H. Chun ◽  
Andrea Salonia ◽  
Giuseppe Zanni ◽  
Andrea Gallina ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Localized Prostate Cancer ◽  
Node Metastases
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