Balloon Catheter Dilatation of Renal Artery Stenosis in the Dog

1978 ◽  
Vol 4 (4) ◽  
pp. 298-302 ◽  
Author(s):  
L. Ekelund ◽  
J. Gerlock, jr. ◽  
V. Goncharenko ◽  
G. Novak
1979 ◽  
Vol 57 (s5) ◽  
pp. 441s-443s ◽  
Author(s):  
G. G. Geyskes ◽  
C. B. A. J. Puylaert ◽  
H. Y. Oei ◽  
J. H. B. Boomsma

1. In 13 patients with hypertension and renal artery stenosis the stenosis was dilated by an intra-arterial balloon catheter under local anaesthesia. 2. In all but one instance arteriography after the dilatation showed considerable widening of the stenosed area. 3. Six patients had a temporary increase of serum creatinine that lasted only a few days. 4. In seven patients, who had a prolonged transit time at renography, this marker of renal blood flow improved after the dilatation. 5. The effect of the dilatation on the blood pressure in this group of patients, selected on arteriographic criteria only, was variable, but comparable with results of renovascular surgery. 6. Dilatation of renal artery stenosis by an intra-arterial balloon catheter is a promising treatment for patients with hypertension and renal artery stenosis. It is a rapid procedure needing only local anaesthesia. Complications in our experience so far are minor.


VASA ◽  
2016 ◽  
Vol 45 (2) ◽  
pp. 175-180 ◽  
Author(s):  
Elias Noory ◽  
Aljoscha Rastan ◽  
Ulrich Beschorner ◽  
Roland Macharzina ◽  
Thomas Zeller

Abstract. Background: The purpose of this study was to assess the correlation between the transstenotic pressure gradient as determined by a pressure wire and the decrease in the intrarenal resistance index (RI) > 0.05 measured by duplex ultrasound in significant unilateral renal artery stenosis (RAS). Intravascular ultrasound (IVUS) was correlated to the angiographic degree of RAS. Patients and methods: In 17 patients, transstenotic pressure gradient measurements, IVUS and RI measurements were obtained before and after stenting. After stenting, graded stenosis was created by progressive balloon catheter inflation. Stenosis severity was expressed as the ratio of the distal pressure (Pd) corrected for aortic pressure (Pa). The balloon inflation pressure was adjusted to create a stenosis with Pd/Pa ratio 1.0 to 0.7. In parallel, RI measurements were performed in the affected kidney and compared to the contralateral kidney for the calculation of the side-difference in RI. IVUS was performed to correlate the cross-sectional degree of stenosis with quantitative angiography (QA). Results: In 60 out 68 measurements, the RI difference (decline > 0.05) correlated with a Pd/Pa ratio < 0.9; this correlation was significant by linear regression analysis (p < 0.001). The preinterventional mean degree of stenosis was 63.4 % + 16.1 (24.6 - 84.6 %) as assessed by QA and 76.7 % + 13.2 % (47 - 92 %) as assessed by IVUS, showing a significant correlation (p < 0.035). Conclusions: In unilateral RAS, a drop in RI > 0.05 as compared to the unaffected kidney correlates to an invasively measured Pd/Pa ratio < 0.9, which is regarded as a significant pressure gradient associated with increased renin production, which promotes renovascular hypertension. QA underestimates RAS severity as compared to IVUS.


1982 ◽  
Vol 23 (3A) ◽  
pp. 177-184 ◽  
Author(s):  
H. Stridbeck ◽  
N. Jonsson ◽  
E. Lindstedt ◽  
L. Ekelund

2002 ◽  
Vol 56 (2) ◽  
pp. 227-231 ◽  
Author(s):  
Nikolaus A. Haas ◽  
Volker Ocker ◽  
Walter Knirsch ◽  
Martin Holder ◽  
Helmut Lochbuehler ◽  
...  

1981 ◽  
Vol 22 (5) ◽  
pp. 561-569 ◽  
Author(s):  
L. Ekelund ◽  
N. Jonsson ◽  
E. Lindstedt ◽  
H. Stridbeck ◽  
S.-B. Lundquist

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