An Echocardiographic and Doppler Study of the Mechanisms of Mitral Regurgitation in Left Ventricular Dilatation

1988 ◽  
Vol 2 (6) ◽  
pp. 313-317 ◽  
Author(s):  
Seymour S. Maze ◽  
Morris N. Kotler ◽  
Wayne R. Parry ◽  
Anthony P. Goldman ◽  
Melvin H. Schwartz
Keyword(s):  
Mitral Regurgitation ◽  
Left Ventricular ◽  
Ventricular Dilatation ◽  
Left Ventricular Dilatation ◽  
Doppler Study

Effect of Progressive Left Ventricular Dilatation on Degree of Mitral Regurgitation Secondary to Mitral Valve Prolapse

2019 ◽  
Vol 123 (11) ◽  
pp. 1887-1888
Author(s):  
William C. Roberts ◽  
Paul A. Grayburn ◽  
Stuart R. Lander ◽  
Dan M. Meyer ◽  
Shelley A. Hall
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Prolapse ◽  
Left Ventricular ◽  
Ventricular Dilatation ◽  
Left Ventricular Dilatation

Atrial functional mitral regurgitation: mechanisms and surgical implications

2020 ◽  
Vol 28 (7) ◽  
pp. 421-426
Author(s):  
Yiting Fan ◽  
Song Wan ◽  
Randolph Hung-Leung Wong ◽  
Alex Pui-Wai Lee
Keyword(s):  
Mitral Regurgitation ◽  
Left Ventricular ◽  
Ventricular Dilatation ◽  
Functional Mitral Regurgitation ◽  
Current Evidence ◽  
Disease Entity ◽  
Risk Of Death ◽  
Left Ventricular Dilatation ◽  
Annular Dilatation ◽  
Increased Risk

The term atrial functional mitral regurgitation refers to a newly recognized disease entity in which mitral regurgitation occurs secondary to left atrial disease, without left ventricular dilatation and intrinsic mitral valve disease, typically in the setting of long-standing atrial fibrillation. Recent evidence suggests that atrial functional mitral regurgitation is associated with increased risk of death and heart failure re-hospitalization. The etiology, pathophysiology, and mechanism of atrial functional mitral regurgitation is not completely understood but they should not be regarded as the same as for the conventional type of functional mitral regurgitation secondary to left ventricular dilatation and dysfunction. Mitral annular dilatation, atriogenic leaflet distortion, insufficient leaflet remodeling, and subtle left ventricular dysfunction may play a role in the pathogenesis of atrial functional mitral regurgitation. The therapeutic and surgical considerations of atrial functional mitral regurgitation are different from those of ventricular functional mitral regurgitation. In this review, we assess current evidence regarding this new disease entity and propose a new surgical approach based on up-to-date understanding and experience of this condition.

scholarly journals Severe Mitral Regurgitation by Hyperthyroidism in the Absence of Left Ventricular Dilatation

2017 ◽  
Author(s):  
Antonio José Lagoeiro Jorge ◽  
Wolney de Andrade Martins ◽  
Eliza de Almeida Gripp ◽  
Breno Macêdo de Almeida ◽  
Camila Cezário Rocha Paz Figueroa ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Left Ventricular ◽  
Ventricular Dilatation ◽  
Severe Mitral Regurgitation ◽  
Left Ventricular Dilatation

scholarly journals Left Ventricular Dilatation and Posterior Papillary Muscle Displacement in an Ex Vivo Pulsatile Model of Functional Mitral Regurgitation

2018 ◽  
Vol 21 (4) ◽  
pp. E275-E280
Author(s):  
Krishaporn Kradangnga ◽  
Eric Monnet
Keyword(s):  
Mitral Regurgitation ◽  
Ex Vivo ◽  
Surgical Techniques ◽  
Left Ventricular ◽  
Ventricular Dilatation ◽  
Functional Mitral Regurgitation ◽  
Heart Model ◽  
Large Patch ◽  
Left Ventricular Dilatation ◽  
Patch Placement

Background: Surgical method of choice for functional mitral regurgitation (FMR) is debatable, since recurrence of FMR post-annuloplasty has been reported in a significant number of cases. Developing a pulsatile FMR heart model by left ventricular dilatation can be a favorable option for usage in the primary stages of developing new surgical techniques that adjunctively targets the posterior papillary muscle (PPM) geometry.Methods: PPM of ex vivo ovine hearts (N = 22) was displaced by three different sizes of patches to induce left ventricular dilatation and FMR. Mitral regurgitation (MR) flow, left ventricular and annular geometry were measured from the dynamic pulsatile flow system before and after patch placement.Results: Outward displacement of PPM was significantly increased in all patch sizes compared to baseline (P = .016, P = .031, and P = .008 from small to large patch, respectively). Left ventricular volume (LVV) significantly increased from 18.53 (15.01-26.03) mL at baseline to 27.5 (19.45-42.46) mL after large patch placement (P = .031). However, the small and medium patch groups did not show significant changes in the LVV after patch placement. MR significantly increased 554 (185-1,919.3) mL/min after applying the large patch compared to baseline (P = .016). There were no significant changes from baseline in MR flow after applying the small and medium patch. Application of the large patch produced the highest proportion of FMR heart models (87.5%, P = .031).Conclusion: The large patch ex vivo pulsatile heart model demonstrated outward displacement of the PPM and significantly produced MR flow. This ex vivo pulsatile heart model can be used to facilitate surgical techniques that targets the PPM displacement in FMR patients.

Autologous skeletal myoblast transplantation attenuates left ventricular dilatation without improving cardiac function

2003 ◽  
Vol 9 (5) ◽  
pp. S1
Author(s):  
Patrick I. McConnell ◽  
Louis Astra ◽  
E.William Schneeberger ◽  
Doug Jacoby ◽  
Jonathan Dinsmore ◽  
...  
Keyword(s):  
Cardiac Function ◽  
Left Ventricular ◽  
Ventricular Dilatation ◽  
Skeletal Myoblast ◽  
Left Ventricular Dilatation ◽  
Myoblast Transplantation

Different Substrates of Non-Sustained Ventricular Tachycardia in Post-infarction Patients With and Without Left Ventricular Dilatation

2010 ◽  
Vol 16 (1) ◽  
pp. 61-68 ◽  
Author(s):  
Gianluca Di Bella ◽  
Claudio Passino ◽  
Giovanni Donato Aquaro ◽  
Daniele Rovai ◽  
Elisabetta Strata ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Left Ventricular ◽  
Sustained Ventricular Tachycardia ◽  
Ventricular Dilatation ◽  
Left Ventricular Dilatation
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