Further Characterization of Serum Alkaline Phosphatase from Male and Female Beagle Dogs

Enzyme ◽  
1989 ◽  
Vol 42 (1) ◽  
pp. 1-7 ◽  
Author(s):  
David Amacher ◽  
Catherine Higgins ◽  
Shelli Schomaker ◽  
Richard Clay
Keyword(s):  
Alkaline Phosphatase ◽  
Serum Alkaline Phosphatase ◽  
Beagle Dogs ◽  
Male And Female

Residual levels and biochemical changes after ventilation with perfluorinated liquid

1975 ◽  
Vol 39 (4) ◽  
pp. 603-607 ◽  
Author(s):  
H. W. Calderwood ◽  
B. C. Ruiz ◽  
M. K. Tham ◽  
J. H. Modell ◽  
S. A. Saga ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Gas Exchange ◽  
Lymph Nodes ◽  
Serum Alkaline Phosphatase ◽  
Biochemical Changes ◽  
Blood Gas ◽  
Beagle Dogs ◽  
Blood Cell Count ◽  
Liquid Ventilation ◽  
Gaseous Oxygen

Twenty-three beagle dogs were ventilated with perfluorinated liquid, perfluoro-1-isopropoxy-hexane (Caroxin-F) for 1 h and were reconverted to gaseous breathing. Hematologic and biochemical changes were studied in five dogs for 1 yr and the remaining animals were followed for evidence of retained Caroxin-F for up to 3 yr. We found that the dogs could be ventilated with liquid Caroxin-F and returned to spontaneous breathing of gaseous oxygen with normal blood gas exchange within 24–72 h. Serum alkaline phosphatase, serum cholesterol, and white blood cell count increased with liquid ventilation but returned to normal in less than 1 wk. Trace amounts of Caroxin-F were detected by chromatography in all tissues studied for the entire 3-yr period. The highest levels of Caroxin-F were found in the lungs and associated lymph nodes. No histologic evidence of the presence of Caroxin-F was seen except for local accumulations of vacuolated macrophages in the lungs and associated lymph nodes. We conclude that Caroxin-F can be breathed without residual deleterious effects, even though trace amounts remained for at least 3 yr.

scholarly journals Characterization of serum alkaline phosphatase separated at or near the origin in polyacrylamide gel using detergents, antibodies and neuraminidase

2008 ◽  
Vol 52 (1) ◽  
pp. 25-27
Author(s):  
Yuji Hirano ◽  
Akiko Kobayashi ◽  
Akira Haruki ◽  
Hiroko Haga ◽  
Mitsumasa Hara ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Serum Alkaline Phosphatase ◽  
Polyacrylamide Gel

scholarly journals Effects of Transport Stress on Serum Alkaline Phosphatase Activity in Beagle Dogs

2013 ◽  
Vol 62 (4) ◽  
pp. 329-332 ◽  
Author(s):  
Takehiro Ochi ◽  
Ippei Nishiura ◽  
Mitsuyoshi Tatsumi ◽  
Yoshimi Hirano ◽  
Kouichi Yahagi ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Serum Alkaline Phosphatase ◽  
Beagle Dogs ◽  
Serum Alkaline Phosphatase Activity ◽  
Transport Stress

Characterization of serum alkaline phosphatase in infancy and childhood

1972 ◽  
Vol 113 (4) ◽  
pp. 289-296 ◽  
Author(s):  
A. Cao ◽  
G. Coppa ◽  
N. Trabalza ◽  
F. Marcucci ◽  
S. Virgiliis ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Serum Alkaline Phosphatase ◽  
Infancy And Childhood

The Clinical, Roentgenological and Morphological Effects of an Acute Exposure of Phosgene on the Lungs of Dogs

1971 ◽  
Vol 29 ◽  
pp. 236-237
Author(s):  
R. F. Bils ◽  
W. F. Diller ◽  
F. Huth
Keyword(s):  
Latent Period ◽  
Chemical Industry ◽  
Toxic Substance ◽  
Lung Edema ◽  
X Rays ◽  
Beagle Dogs ◽  
Male And Female ◽  
Morphological Alterations ◽  
Before And After ◽  
Electron Microscopes

Phosgene still plays an important role as a toxic substance in the chemical industry. Thiess (1968) recently reported observations on numerous cases of phosgene poisoning. A serious difficulty in the clinical handling of phosgene poisoning cases is a relatively long latent period, up to 12 hours, with no obvious signs of severity. At about 12 hours heavy lung edema appears suddenly, however changes can be seen in routine X-rays taken after only a few hours' exposure (Diller et al., 1969). This study was undertaken to correlate these early changes seen by the roengenologist with morphological alterations in the lungs seen in the'light and electron microscopes.Forty-two adult male and female Beagle dogs were selected for these exposure experiments. Treated animals were exposed to 94.5-107-5 ppm phosgene for 10 min. in a 15 m3 chamber. Roentgenograms were made of the thorax of each animal before and after exposure, up to 24 hrs.

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