Neurophysiological Monitoring and Awake Craniotomy for Resection of Intracranial Gliomas

Author(s):  
Taiichi Saito ◽  
Manabu Tamura ◽  
Mikhail F. Chernov ◽  
Soko Ikuta ◽  
Yoshihiro Muragaki ◽  
...  
2019 ◽  
pp. 355-362
Author(s):  
Mihaela Cosman ◽  
Ionut Mihail Pantiru ◽  
Bogdan Florin Iliescu ◽  
Nina Straticiuc ◽  
Iulia Aldea ◽  
...  

Introduction. Despite the technological development lesion located in or near language area still represent a challenge for every neurosurgeon. Awake craniotomy and intraoperative neurophysiological monitoring come to our help. Different techniques variation exists among specialized centres. We present our experience and the set up for this procedure. Materials and methods. We conducted a retrospective analysis of collected data from 10 patients with brain tumours located in or near language area to which we performed awake craniotomy and intraoperative neurophysiological monitoring. They were admitted in Third Department of Neurosurgery,” Prof. Dr. N. Oblu” Emergency Clinical Hospital, Yassi, Romania, between January 2014 and July 2018. Results. Presenting symptoms had a duration more than a month in 60 % of patients. In 80% of them were represented by epileptic seizures and the rest of 20 % had transient aphasia elements. The median age of presentation was 28 years old with a male dominance. The histological reports indicated: fibrillary astrocytoma – 40%, anaplastic astrocytoma – 30%, oligodendroglioma – 20% and metastases – 10%. Gross total resection was performed in half of the cases and subtotal in just one case, in which the spontaneous speech and object naming showed repeated impairment in time of tumour debulking. The surgical intervention was well tolerated by all the patients. The intensity of cortical stimulation used was between 4 – 10 mA. Postoperatively two patients had neurological aggravation, with full recovery at 3 months follow up period, two were stationary and six had symptoms remission. Conclusion. A young age of presentation, a paucity of symptoms, the chance for an increase in overall survival and progression free survival impose the need for direct communication and feedback with the patient in time of tumour resection. Thus, awake craniotomy and intraoperative neurophysiological monitoring is the golden standard for selected cases of language area tumours.


2021 ◽  
Vol 56 (2) ◽  
pp. 171-178
Author(s):  
Vishwaraj Ratha ◽  
Nishanth Sampath ◽  
Sudhakar Subramaniam ◽  
V.R. Roopesh Kumar

<b><i>Introduction:</i></b> Unlike adult gliomas, the utility of combined application of awake anesthesia and intraoperative neurophysiological monitoring (IONM) for maximal safe resection in eloquent region gliomas (ERG) has not been established for pediatric population while it remains unexplored in preadolescents (below 11 years old). <b><i>Case Presentation:</i></b> We report 2 cases of awake craniotomy with IONM in an 8 and 9 year old for safe maximal resection of ERG. In both the cases, repeated preoperative visits of the operating room was performed to familiarize and educate the children about intraoperative communication, comfortable positioning, and neurological assessment. Under conscious sedation protocol, cortical and subcortical mapping, and electrocorticography, gross total resection was achieved. In both the cases, there were no postoperative neurodeficits or perioperative complications. <b><i>Conclusion:</i></b> Our 2 cases illustrate the first instance of successful use of awake IONM for maximal safe resection of ERG in preadolescent age-group. We believe, with proper preoperative planning and careful titration of anesthetics, it is safe and feasible. The blanket notion that preadolescent age-group should be excluded from awake mapping needs to be challenged, rather curated on a case basis.


2014 ◽  
Vol 125 (5) ◽  
pp. e14
Author(s):  
Peter Milos ◽  
Hans Lindehammar ◽  
Kerstin Metcalf ◽  
Sverre Boström

Author(s):  
Inga Batinica ◽  
K. Rotim ◽  
T. Sajko ◽  
M. Schonwald ◽  
S. Salkičević

2018 ◽  
Vol 4 (5) ◽  
pp. 369-371
Author(s):  
Rajashree U Gandhe . ◽  
Chinmaya P Bhave . ◽  
Avinash S Kakde . ◽  
Neha T Gedam .

2019 ◽  
Vol 1 (1) ◽  
pp. 21-24
Author(s):  
Ricardo de Amoreira Gepp ◽  
Marco Rolando Sainz Quiroga ◽  
Henrique Caetano de Souza ◽  
Marcio de Mendonça Cardoso

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