Determination of Salivary ABH-Blood Group Antigens by Rocket Affmoelectrophoresis

Vox Sanguinis ◽  
1982 ◽  
Vol 42 (3) ◽  
pp. 124-130
Author(s):  
Lennart Lindqvist
Keyword(s):  
Blood Group ◽  
Blood Group Antigens ◽  
Abh Blood Group Antigens

BLOOD GROUP AND HUMAN DISEASES (REVIEW OF LITERATURE)

2020 ◽  
Vol 65 (4) ◽  
pp. 216-221
Author(s):  
Frida Nasyrovna Gilmiyarova ◽  
N. A. Kolotyeva ◽  
V. I. Kuzmicheva ◽  
O. A. Gusyakova ◽  
I. A. Borodina ◽  
...  
Keyword(s):  
Blood Group ◽  
Gastrointestinal Diseases ◽  
Antigenic Determinants ◽  
Blood Group Antigens ◽  
Oral Diseases ◽  
Group Type ◽  
Pathological Conditions ◽  
Definition Of ◽  
Meta Analyses

AB0 blood group antigens were discovered over a century ago; however, it is still important to study their role in development of various pathological conditions. Today it is known that antigenic determinants of this blood group are present not only on erythrocyte membrane but also on other cells and tissues: platelets, gastrointestinal epithelium and salivary glands, respiratory system cells. In the last decade, a large number of studies have appeared to reveal the relationship between a specific disease and blood group type, meta-analyses have been published. Previously, the authors have studied the metabolic status, cell composition and coagulation profile of clinically healthy individuals for more than on 180,000 donations, that allowed to identify group-specific features for each blood group. This review presents generalized data on the association of such pathological conditions as coronary heart disease, thromboembolic complications, tumors of various localizations, inflammatory and destructive oral diseases, psychiatric and some infectious diseases with the presence or absence of antigenic determinants A and B. Carriers of blood group 0 (I) are generally more resistant to diseases, with the exception of H.pylori-associated gastrointestinal diseases. Carriers of «antigenic» blood groups A (II), B (III), AB (IV) are more susceptible to development of infectious, cardiovascular and cancer diseases. The presented data demonstrate clinical significance of the definition of group typing not only for selection of blood and its components during transfusion and transplantation, but also for diagnostics, determination of risk group and tactics for treatment patients with different nosologies.

Determination of homozygote vs heterozygote of Rh blood group antigens via rosette assays

Transfusion ◽  
1982 ◽  
Vol 22 (3) ◽  
pp. 194-196 ◽  
Author(s):  
AB Loren ◽  
Y Matsuo ◽  
D Charman ◽  
MM Yokoyama
Keyword(s):  
Blood Group ◽  
Blood Group Antigens ◽  
Rh Blood Group

scholarly journals Identification of Aptamers that Specifically Bind to A1 Antigen by Performing Cell-on Human Erythrocytes

2020 ◽  
Vol 9 ◽  
pp. 1657
Author(s):  
Seyed Mohammad Hasan Hosseini ◽  
Mohammad Reza Bassami ◽  
Alireza Haghparast ◽  
Mojtaba Sankian ◽  
Gholamreza Hashemi Tabar
Keyword(s):  
Blood Group ◽  
Dna Aptamer ◽  
Diagnostic Tools ◽  
Blood Group Antigens ◽  
Apparent Dissociation Constant ◽  
Fluorescent Intensity ◽  
Target Molecules ◽  
Polymerase Chain ◽  
Dissociation Constant Kd

Background: The apply of aptamers as a new generation’s way to probe diagnostic for the detection of target molecules has gained ground. Aptamers can be used as alternatives to diagnostic antibodies for detection of blood groups due to their unique features. This study was aimed to produce DNA diagnostic aptamer detecting the antigen of A1 blood group using the Cell-Selex method. Materials and Methods: DNA aptamer was isolated against A1 RBC antigen after ten stages of Cell-Selex and amplification by an asymmetric polymerase chain reaction. The progress of the stages of selection was evaluated using flow cytometry analysis, which the DNA aptamer isolated from the tenth cycle with an affinity of 70% fluorescent intensity, was selected from four positive colonies followed by determination of the sequences and secondary structures. Results: The aptameric sequence obtained from C4 cloning was calculated with the highest binding affinity to A1 antigen having an apparent dissociation constant (Kd value) of at least 29.5 ± 4.3 Pmol, which was introduced as the selected aptamer-based on ΔG obtained from a colony of C4 equal to –13.13. Conclusion: The aptamer obtained from using Cell-Selex method could be used as an example for the development of diagnostic tools such as biosensors for detecting A1 blood group antigens. [GMJ.2020;9:e1657] 

ABH blood group antigens in O-glycans of human glycophorin A

2004 ◽  
Vol 429 (2) ◽  
pp. 145-153 ◽  
Author(s):  
Maria Podbielska ◽  
Sten-Åke Fredriksson ◽  
Bo Nilsson ◽  
Elwira Lisowska ◽  
Hubert Krotkiewski
Keyword(s):  
Blood Group ◽  
Glycophorin A ◽  
Blood Group Antigens ◽  
Abh Blood Group Antigens ◽  
Human Glycophorin
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