Effect of Maternal Protein Deficiency on Intrauterine Development of Small Intestine with Special Reference to Alkaline Phosphatase

Enzyme ◽  
1978 ◽  
Vol 23 (3) ◽  
pp. 194-200 ◽  
Author(s):  
A. Subramoniam
Author(s):  
Jacob Bamaiyi ◽  
Omajali ◽  
Sanni Momoh

This study investigates the effects of kanwa on rat gastrointestinal phosphatases. The rats were administered 7% w/v concentration of  trona (Kanwa) orally for a period of two weeks in order to investigate how this compound is being used as food additive in some homes in Nigeria. The Kanwa used in this study was the handpicked variety obtained from sellers from Anyigba market in eastern part of Kogi State, Nigeria. Kanwa, a hydrated sodium carbonate (Na2CO3NaHCO3.2H2O) was obtained as a dried lake salt. Acid phosphatase has the ability to dephosphorylate molecules containing phosphate group. The decreased and elevated level in serum or plasma acid and alkaline phosphatases serves as diagnostic indices for various diseases. Results showed that there was increase and decrease of acid phosphatase (ACP) activities in both the stomach and small intestine. The activities of alkaline phosphatase (ALP) fluctuated in the small intestine. However, in the stomach, an increase activity of ALP was noticed throughout the period of ‘Kanwa’ administration. We concluded that although the level of ‘Kanwa’ consumed in most homes may not be toxic if not taken continuously or repeatedly. Thus, continuous consumption should be discouraged as accumulation of high level of ‘Kanwa’ may cause damages or injuries to the various organs/tissues and may disrupt normal body function.


Kanzo ◽  
1977 ◽  
Vol 18 (5) ◽  
pp. 314-318
Author(s):  
Hideo NISHIMURA ◽  
Daizo KAN ◽  
Junsuke NAWATA ◽  
Mituru ODAWARA ◽  
Mikio HAYAKAWA ◽  
...  

1998 ◽  
Vol 128 (11) ◽  
pp. 1869-1877 ◽  
Author(s):  
Takeshi Nikawa ◽  
Kazuhito Rokutan ◽  
Kayo Nanba ◽  
Kaori Tokuoka ◽  
Shigetada Teshima ◽  
...  

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