Whole-Slide Imaging in Cytopathology

2020 ◽  
pp. 84-90
Author(s):  
Zaibo Li ◽  
Michael Quick ◽  
Liron Pantanowitz
Keyword(s):  
Whole Slide Imaging

scholarly journals Histological assessment of granulomas in natural and experimental Schistosoma mansoni infections using whole slide imaging

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0184696 ◽  
Author(s):  
Kátia B. Amaral ◽  
Thiago P. Silva ◽  
Felipe F. Dias ◽  
Kássia K. Malta ◽  
Florence M. Rosa ◽  
...  
Keyword(s):  
Schistosoma Mansoni ◽  
Whole Slide Imaging ◽  
Histological Assessment

Evaluation of 2 whole-slide imaging applications in dermatopathology

2008 ◽  
Vol 39 (9) ◽  
pp. 1341-1349 ◽  
Author(s):  
Nicole Velez ◽  
Drazen Jukic ◽  
Jonhan Ho
Keyword(s):  
Whole Slide Imaging

scholarly journals Whole slide imaging for educational purposes

2012 ◽  
Vol 3 (1) ◽  
pp. 46 ◽  
Author(s):  
Liron Pantanowitz ◽  
Janusz Szymas ◽  
David Wilbur ◽  
Yukako Yagi
Keyword(s):  
Whole Slide Imaging

scholarly journals Transform- and multi-domain deep learning for single-frame rapid autofocusing in whole slide imaging

2018 ◽  
Vol 9 (4) ◽  
pp. 1601 ◽  
Author(s):  
Shaowei Jiang ◽  
Jun Liao ◽  
Zichao Bian ◽  
Kaikai Guo ◽  
Yongbing Zhang ◽  
...  
Keyword(s):  
Deep Learning ◽  
Whole Slide Imaging ◽  
Single Frame

scholarly journals Integrated Pathology Informatics Enables High-Quality Personalized and Precision Medicine: Digital Pathology and Beyond

2017 ◽  
Vol 142 (3) ◽  
pp. 369-382 ◽  
Author(s):  
Zoya Volynskaya ◽  
Hung Chow ◽  
Andrew Evans ◽  
Alan Wolff ◽  
Cecilia Lagmay-Traya; ◽  
...  
Keyword(s):  
Data Collection ◽  
Precision Medicine ◽  
Critical Role ◽  
Digital Pathology ◽  
Geographic Area ◽  
Whole Slide Imaging ◽  
High Quality ◽  
Pathology Informatics ◽  
Prognosis And Prediction ◽  
The Right

Context.— The critical role of pathology in diagnosis, prognosis, and prediction demands high-quality subspecialty diagnostics that integrates information from multiple laboratories. Objective.— To identify key requirements and to establish a systematic approach to providing high-quality pathology in a health care system that is responsible for services across a large geographic area. Design.— This report focuses on the development of a multisite pathology informatics platform to support high-quality surgical pathology and hematopathology using a sophisticated laboratory information system and whole slide imaging for histology and immunohistochemistry, integrated with ancillary tools, including electron microscopy, flow cytometry, cytogenetics, and molecular diagnostics. Results.— These tools enable patients in numerous geographic locations access to a model of subspecialty pathology that allows reporting of every specimen by the right pathologist at the right time. The use of whole slide imaging for multidisciplinary case conferences enables better communication among members of patient care teams. The system encourages data collection using a discrete data synoptic reporting module, has implemented documentation of quality assurance activities, and allows workload measurement, providing examples of additional benefits that can be gained by this electronic approach to pathology. Conclusion.— This approach builds the foundation for accurate big data collection and high-quality personalized and precision medicine.

scholarly journals A Practical Guide to Whole Slide Imaging: A White Paper From the Digital Pathology Association

2018 ◽  
Vol 143 (2) ◽  
pp. 222-234 ◽  
Author(s):  
Mark D. Zarella ◽  
Douglas Bowman; ◽  
Famke Aeffner ◽  
Navid Farahani ◽  
Albert Xthona; ◽  
...  
Keyword(s):  
Practical Knowledge ◽  
Digital Pathology ◽  
Executive Leadership ◽  
The United States ◽  
White Paper ◽  
Primary Diagnosis ◽  
Basic Function ◽  
Whole Slide Imaging ◽  
Interinstitutional Collaboration ◽  
Glass Slides

Context.— Whole slide imaging (WSI) represents a paradigm shift in pathology, serving as a necessary first step for a wide array of digital tools to enter the field. Its basic function is to digitize glass slides, but its impact on pathology workflows, reproducibility, dissemination of educational material, expansion of service to underprivileged areas, and intrainstitutional and interinstitutional collaboration exemplifies a significant innovative movement with far-reaching effects. Although the benefits of WSI to pathology practices, academic centers, and research institutions are many, the complexities of implementation remain an obstacle to widespread adoption. In the wake of the first regulatory clearance of WSI for primary diagnosis in the United States, some barriers to adoption have fallen. Nevertheless, implementation of WSI remains a difficult prospect for many institutions, especially those with stakeholders unfamiliar with the technologies necessary to implement a system or who cannot effectively communicate to executive leadership and sponsors the benefits of a technology that may lack clear and immediate reimbursement opportunity. Objectives.— To present an overview of WSI technology—present and future—and to demonstrate several immediate applications of WSI that support pathology practice, medical education, research, and collaboration. Data Sources.— Peer-reviewed literature was reviewed by pathologists, scientists, and technologists who have practical knowledge of and experience with WSI. Conclusions.— Implementation of WSI is a multifaceted and inherently multidisciplinary endeavor requiring contributions from pathologists, technologists, and executive leadership. Improved understanding of the current challenges to implementation, as well as the benefits and successes of the technology, can help prospective users identify the best path for success.

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